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Compound preparation for mainly treating coronary heart disease and preparation method thereof

A compound preparation and a technology for coronary heart disease, applied in the field of medicine, can solve the problems of low scientific and technological content, backward production technology in the traditional Chinese medicine industry, and low level of modernization, and achieve the effects of high safety, no toxic side effects, and remarkable curative effect.

Inactive Publication Date: 2019-12-03
新疆华春生物药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, due to the low modernization level of the traditional Chinese medicine industry and other reasons, the Chinese medicine industry generally has many problems such as backward production technology, unstable product quality, and low technological content, resulting in weak international market competitiveness of the Chinese medicine industry, and the Chinese medicine industry is facing severe challenges.

Method used

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  • Compound preparation for mainly treating coronary heart disease and preparation method thereof
  • Compound preparation for mainly treating coronary heart disease and preparation method thereof

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preparation example Construction

[0034] The embodiment of the present invention also provides a preparation method of a compound preparation for mainly treating coronary heart disease, comprising the following steps:

[0035] Each component was weighed according to the above-mentioned formula of the compound preparation for mainly treating coronary heart disease, and set aside.

[0036] The motherwort, seabuckthorn leaves, chuanxiong, shenxiangcao, xintahua and red peony are dried and pulverized respectively, and passed through a 50-120 mesh sieve to obtain a pulverized mixed material.

[0037] Put the pulverized mixed material into a container, add 4 to 8 times the amount of water as the raw material, decoct for 2 to 2.5 hours, and filter to obtain water extract and filter residue.

[0038] The water extract is subjected to ultrafiltration to obtain an ultrafiltered extract.

[0039] Adding 5-6 times the ethanol solution to the filter residue to carry out reflux extraction for 1-2 times, and combining the r...

Embodiment 1

[0051] The compound preparation for treating mainly coronary heart disease according to the embodiment of the present invention is prepared by the following steps:

[0052] According to the following formula, the raw materials were weighed in parts by weight for use: 10 parts of motherwort, 6 parts of seabuckthorn leaves, 10 parts of Chuanxiong, 16 parts of herba, 15 parts of xintahua and 10 parts of red peony.

[0053] The motherwort, seabuckthorn leaves, Chuanxiong, Shenxiangcao, xintahua and red peony are dried and pulverized respectively, and passed through a 50-mesh sieve to obtain a pulverized mixed material. Put the pulverized mixed material into a container, add 6 times the amount of water of the raw material, decoct for 2.5 hours, and filter to obtain a water extract and filter residue. Use a filter membrane with a molecular cut-off of 50,000 for ultrafiltration, keep the temperature of the water extract at 55°C, and use cross-flow filtration as the filtration method....

Embodiment 2

[0055] The compound preparation for treating mainly coronary heart disease according to the embodiment of the present invention is prepared by the following steps:

[0056] According to the following formula, the raw materials were weighed in parts by weight for use: 7 parts of motherwort, 15 parts of seabuckthorn leaves, 3 parts of Chuanxiong, 4 parts of herba, 10 parts of xintahua and 8 parts of red peony.

[0057] The motherwort, seabuckthorn leaves, chuanxiong, shenxiangcao, xintahua and red peony are dried and pulverized respectively, and passed through a 100-mesh sieve to obtain a pulverized mixed material. Put the pulverized mixed material into a container, add 4 times the amount of water as the raw material, decoct for 2.5 hours, and filter to obtain water extract and filter residue. Use a filter membrane with a molecular cut-off of 50,000 to carry out ultrafiltration, keep the temperature of the water extract at 45°C, and use cross-flow filtration as the filtration me...

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Abstract

The invention belongs to the field of medicines, and provides a compound preparation for mainly treating coronary heart disease and a preparation method thereof, the compound preparation for treatingcoronary heart disease comprises the following components in parts by weight: 7-19 parts of motherwort, 6-15 parts of sea-buckthorn leaves, 3-13 parts of ligusticum wallichii, 4-16 parts of hyssopus officinalis, 10-20 parts of Ziziphora bungeana and 8-17 parts of radix paeoniae rubra. The compound preparation has the functions of promoting blood circulation to remove meridian obstruction, removingblood stasis to promote tissue regeneration and clearing away the heart-fire to relieve restlessness through the reasonable proportion and synergistic effect of motherwort, sea-buckthorn leaves, ligusticum wallichii, hyssopus officinalis, Ziziphora bungeana and radix paeoniae rubra, is mainly used for treating diseases such as precordial pain, palpitation, chest distress and shortness of breath,the curative effect is obvious, no toxic and side effect is generated, and the product is high in safety.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a compound preparation for mainly treating coronary heart disease and a preparation method thereof. Background technique [0002] Coronary atherosclerotic heart disease is a heart disease caused by atherosclerotic lesions in the coronary arteries that cause stenosis or blockage of the vessel lumen, resulting in myocardial ischemia, hypoxia or necrosis. It is often called "coronary heart disease". According to statistics, the prevalence rate of coronary heart disease is 1.59% in cities, 0.48% in rural areas, 0.77% in total, showing an upward trend. Coronary heart disease is the number one cause of death in the United States and many developed countries. [0003] As the limitations of western medicine are gradually recognized by people and the world's disease spectrum and medical model are changing, advocating natural medicine is becoming a worldwide trend, and the Chinese me...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61K36/65A61P9/10
CPCA61K36/185A61K36/236A61K36/53A61K36/533A61K36/65A61K36/71A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61P9/10A61K2300/00
Inventor 李成功邓洁文胡时先库丽夏西·玛尼周立东左明明
Owner 新疆华春生物药业股份有限公司
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