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Preparation method of soft capsule with auxiliary liver protection effect

A technology for soft capsules and liver protection, which is applied in the directions of capsule delivery, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc. beautiful effect

Active Publication Date: 2019-11-26
SHAANXI PANLONG PHARMACEUTICAL GROUP LIMITED BY SHARE LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are not many products that have auxiliary protective functions against chemical liver damage and have achieved good social and economic benefits. Therefore, the development of health foods that have auxiliary protective functions against chemical liver damage has broad application prospects.

Method used

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  • Preparation method of soft capsule with auxiliary liver protection effect
  • Preparation method of soft capsule with auxiliary liver protection effect
  • Preparation method of soft capsule with auxiliary liver protection effect

Examples

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Comparison scheme
Effect test

Embodiment 1

[0036] A preparation method of auxiliary liver-protecting soft capsules, the raw materials include the following ingredients: Hovenia dulcis fruit 950g, Schisandra chinensis 300g, soybean oil 380g, gelatin 150g, purified water 150g, glycerin 60g, beeswax 20g, red iron oxide 0.9g,

[0037] The preparation method comprises the following steps:

[0038] Step 1. Place 950g Hovenia dulcis and 300g Schisandra chinensis in 70% ethanol solution for reflux extraction for 2 times, filter and combine the filtrates, and put the combined filtrates at a pressure of -0.065MPa and a temperature of 65°C Recover ethanol and concentrate to extract with a relative density of 1.20. Dry the extract at a pressure of -0.085MPa and a temperature of 65°C for 70 minutes to a constant weight to obtain 113.38g of dry extract, crush the dry extract and pass through a 120-mesh sieve , to obtain 113.38g dry paste powder; the quality of ethanol solution used for each reflux extraction is 6 times of the total ...

Embodiment 2

[0043] A preparation method of auxiliary liver-protecting soft capsules, the raw materials include the following ingredients: Hovenia dulcis fruit 950g, Schisandra chinensis 300g, soybean oil 380g, gelatin 150g, purified water 150g, glycerin 60g, beeswax 20g, red iron oxide 0.9g,

[0044] The preparation method comprises the following steps:

[0045] Step 1. Place 950g Hovenia dulcis and 300g Schisandra chinensis in 70% ethanol solution for reflux extraction twice, filter and combine the filtrates, and put the combined filtrates at a pressure of -0.075MPa and a temperature of 65°C Recover ethanol and concentrate to extract with a relative density of 1.25. Dry the extract at a pressure of -0.085MPa and a temperature of 65°C for 70 minutes to a constant weight to obtain 113.13g of dry extract, crush the dry extract and pass through a 120-mesh sieve , to obtain 113.13g of dry paste powder; the quality of the ethanol solution used for each reflux extraction is 6 times of the total...

Embodiment 3

[0050] A preparation method of auxiliary liver-protecting soft capsules, the raw materials include the following ingredients: Hovenia dulcis fruit 950g, Schisandra chinensis 300g, soybean oil 400g, gelatin 150g, purified water 150g, glycerin 60g, beeswax 15g, red iron oxide 0.9g,

[0051] The preparation method comprises the following steps:

[0052] Step 1. Place 950g Hovenia dulcis and 300g Schisandra chinensis in 60% ethanol solution for reflux extraction for 3 times, filter and combine the filtrates, and put the combined filtrates at a pressure of -0.07MPa and a temperature of 65°C Recover ethanol and concentrate to extract with a relative density of 1.22. Dry the extract at a pressure of -0.085 MPa and a temperature of 50°C for 100 minutes to a constant weight to obtain 113.25 g of dry extract, crush the dry extract and pass through a 100-mesh sieve , to obtain 113.25g dry paste powder; the quality of ethanol solution used for each reflux extraction is 8 times of the tota...

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Abstract

The invention discloses a preparation method of a soft capsule with an auxiliary liver protection effect. The preparation method is characterized in that raw materials of the soft capsule comprise ingredients in parts by weight as follows: 920-970 parts of semen hoveniae, 280-310 parts of Chinese magnoliavine fruits, 340-400 parts of soybean oil, 125-165 parts of gelatin, 150 parts of purified water, 40-105 parts of glycerin, 15-30 parts of beeswax and 0.7-1.2 parts of red iron oxide. The preparation method comprises steps as follows: performing reflux extraction on the semen hoveniae and theChinese magnoliavine fruits to obtain dry extract powder, preparing a capsule solution and a colloidal solution, and pressing the solutions to obtain pills. The soft capsule prepared with the method takes the semen hoveniae and the Chinese magnoliavine fruits as main ingredients and the soybean oil, gelatin, glycerin, beewax and red iron oxide as auxiliary materials, has the auxiliary liver protection effect and can enter intestines and stomach of a human body to be rapidly disintegrated and absorbed by the human body, thereby achieving the purpose of effectiveness with effective blood concentration.

Description

technical field [0001] The invention belongs to the technical field of preparation of health care products, and in particular relates to a preparation method of auxiliary liver-protecting soft capsules. Background technique [0002] Chemical liver damage is liver damage caused by chemical hepatotoxic substances. The liver, as an important detoxification organ of the human body, has a strong defense and detoxification function against toxins from the outside and the body's own metabolism. Chemical substances can pass through the gastrointestinal tract. Portal or systemic circulation enters the liver for transformation, so the liver is vulnerable to toxic substances in chemicals. Chemical hepatotoxic substances include alcohol, chemical poisons in the environment, and certain drugs. With the development of society, all kinds of industrial pollution, changes in diet structure, such as polluted air, water, food, medicine, drinking and other harmful chemicals will cause the huma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/79A61K36/72A61K9/48A61K47/44A61K47/10A61P1/16A23L33/00A23P10/30
CPCA23V2002/00A61K9/4858A61K36/57A61K36/72A61K36/79A61K2236/333A61K2236/39A61K2236/51A23L33/00A23P10/30A61P1/16A61K2300/00A23V2200/30
Inventor 谢晓林张德柱刘鹏
Owner SHAANXI PANLONG PHARMACEUTICAL GROUP LIMITED BY SHARE LTD
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