Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine composition with protective function on alcoholic liver injury and preparation method thereof

A technology for alcohol-induced liver injury and protective function, which can be applied in drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., and can solve problems such as acute alcoholism

Inactive Publication Date: 2019-11-22
JILIN ACAD OF TRADITIONAL CHINESE MEDICINE
View PDF2 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Drinking a lot of alcohol at one time often leads to acute alcoholism

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition with protective function on alcoholic liver injury and preparation method thereof
  • Traditional Chinese medicine composition with protective function on alcoholic liver injury and preparation method thereof
  • Traditional Chinese medicine composition with protective function on alcoholic liver injury and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] 2 parts of kudzu root, 2 parts of Hovenia dulcis, 2 parts of white peony, 2 parts of licorice;

[0017] Take the above-mentioned proportion of raw materials by weight and feed, soak for 30 minutes, extract with 8 times the amount of water three times, each time for 1 hour, filter, concentrate under reduced pressure, 70°C, -0.06Mpa, and measure 1.05 when the relative density reaches 60°C; Spray drying, the inlet air temperature is 150°C, and the outlet air temperature is 80°C to obtain dry cream powder.

Embodiment 2

[0019] 6 parts of kudzu root, 5 parts of Hovenia dulcis, 7 parts of white peony, 6 parts of licorice;

[0020] Feed the above-mentioned proportion of raw materials by weight, soak for 30 minutes, extract with 8 times the amount of water three times, each time for 1 hour, filter, concentrate under reduced pressure, 72.5°C, -0.07Mpa, and measure 1.08 when the relative density reaches 60°C; Spray drying, the inlet air temperature is 155°C, and the outlet air temperature is 82.5°C to obtain dry cream powder.

Embodiment 3

[0022] 10 parts of kudzu root, 9 parts of Hovenia dulcis, 10 parts of white peony, 9 parts of licorice;

[0023] Feed the above-mentioned proportion of raw materials by weight, soak for 30 minutes, extract with 8 times the amount of water three times, each time for 1 hour, filter, concentrate under reduced pressure, 75°C, -0.08Mpa, and measure 1.10 when the relative density reaches 60°C; Spray drying, the inlet air temperature is 160°C, and the outlet air temperature is 85°C to obtain dry cream powder.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a traditional Chinese medicine composition with a protective function on alcoholic liver injury and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from, by weight, 2-10 parts of radix puerariae, 2-10 parts of hovenia dulcis thunb, 2-10 parts of radix paeoniae alba and2-10 parts of licorice root. The traditional Chinese medicine composition has the effects of relieving alcoholism, helping produce saliva and slaking thirst, smoothing liver and relieving pain. The traditional Chinese medicine theory and the modern scientific theory serve as guidance, L9(34) orthogonal compatibility testing is used, the compatibility proportion of the raw material components is determined with extremely-low-density lipoprotein in serum of miceand malonaldehyde and glutathione in the liver as indexes, and the traditional Chinese medicine composition with the protective function on alcoholic liver injury is prepared. Pharmacodynamic research shows that the composition can be used for improving related indexes of the acute and subacute alcoholic liver injury mice. The composition is suitable for boozy people, and is clear in effective component and controllable in quality.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition, which has a protective function against alcoholic liver damage and a preparation method. Background technique [0002] Alcoholic liver injury mainly refers to alcoholic fatty liver, alcoholic hepatitis, alcoholic liver fibrosis and alcoholic liver cirrhosis. Extensive liver cell necrosis or even liver failure can be induced in severe alcoholism. Alcoholic liver disease is the most common liver disease in western countries, and its incidence is increasing in our country. [0003] Drinking more alcohol at one time often leads to acute alcoholism. After acute alcoholism, it is often accompanied by various physical discomforts such as headache, nausea, and general fatigue, which may be life-threatening in severe cases. Chronic alcoholism (alcohol dependence) is also a disease, which is a systemic syndrome caused by th...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/72A61K9/20A61P1/16
CPCA61K9/2054A61K36/484A61K36/488A61K36/65A61K36/71A61K36/72A61K2236/331A61K2236/39A61K2236/51A61P1/16A61K2300/00
Inventor 赵宏宇王玉张凤清邸琳刘新宇
Owner JILIN ACAD OF TRADITIONAL CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products