Preparation method of antibacterial dressing
A technology of antibacterial drugs and water-soluble polymers, which is applied in medical science, bandages, absorbent pads, etc., can solve the problems of uneven distribution of antibacterial drugs, uneven release of antibacterial drugs, and inability to achieve antibacterial effects, so as to prevent and treat wounds. Infection, wide range of use, and low cost effects
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Embodiment 1
[0025] A kind of preparation method of antibacterial dressing, concrete steps are as follows:
[0026] 1. Dissolve 50 μg of antibiotics and 100 μg of PEG1000 polymer in 100 mL of dichloromethane solvent, stir and dissolve completely, and let stand at room temperature for 10 minutes to obtain a solution composition containing antibacterial drugs;
[0027] 2. Slowly place the 10×10cm hydrogel dressing in the solution composition containing antibacterial drugs, soak for 5 minutes, take it out and let it stand at room temperature for 30 minutes to obtain a hydrogel dressing containing antibiotics;
[0028] 3. Dissolve 200 μg of PEG1000 polymer in 13 mL of water, stir and dissolve completely, and let it stand at room temperature for 10 minutes to obtain a PEG1000 polymer solution. Use a brush to apply the PEG1000 polymer solution to the antibiotic-containing hydrogel dressing obtained in step 2. On the antibiotic drug coating, let stand at room temperature for 50 minutes;
[0029]...
Embodiment 2
[0031] A kind of preparation method of antibacterial dressing, concrete steps are as follows:
[0032] 1. Dissolve 1000 μg of sulfonamide and 50 μg of PEG1000 polymer in 10 mL of ethanol solvent, stir and dissolve completely, and let stand at room temperature for 10 minutes to obtain a pharmaceutical solution composition containing sulfonamide;
[0033] 2. Slowly place the 5×6cm foam dressing in the sulfa drug-containing solution composition, soak for 1 minute, take it out and let it stand at room temperature for 60 minutes, and obtain the sulfa drug-containing foam gel dressing;
[0034] 3. Dissolve 200 μg of PEG1000 polymer in 13 mL of water, stir and dissolve completely, and let stand at room temperature for 10 minutes to obtain a PEG1000 polymer solution. Use a brush to apply the PEG1000 polymer solution to the sulfa drug-containing foam gel dressing obtained in step 2. On the antibacterial drug coating, stand at room temperature for 100 minutes;
[0035] 4. Repeat steps ...
Embodiment 3
[0037] A kind of preparation method of antibacterial dressing, concrete steps are as follows:
[0038] 1. Dissolve 10 μg of miconazole and 50 μg of PEO polymer in 1000 mL of acetone solvent, stir and dissolve completely, and let stand at room temperature for 10 minutes to obtain a pharmaceutical solution composition containing miconazole;
[0039] 2. Apply the miconazole-containing drug solution composition to the surface of the 5×8 cm alginate dressing with a roller, roll it at least twice, and let it stand at room temperature for 60 minutes to obtain the miconazole-containing drug alginate dressing;
[0040] 3. Dissolve 5 μg of PVA polymer in 10 mL of water, stir and dissolve completely, and let it stand at room temperature for 10 minutes to obtain a PVA polymer solution. Use a brush to apply the PVA polymer solution to the miconazole-containing drug alginate obtained in step 2. On the miconazole drug coating of the dressing, let stand at room temperature for 10 minutes;
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