Electric pulse ablation device and simulation method suitable for electric pulse ablation device

Abstract

The present invention discloses an electric pulse ablation device and a simulation method suitable for the electric pulse ablation device, and belongs to the technical field of electric pulse devices.The prior art has the following defects: in existing electric pulse ablation process, due to the impedance of tumor tissues, electrolyte parameters of tissue infiltration liquid of an ablation area change along with ablation time and the changed electrolyte parameters are not matched with the initial electric pulse ablation parameters any more, so that an ablation effect is poor. A pressure sensor module conduct early warning on a puncture process to avoid damage of normal organ tissues; and a positioning system can conduct positioning navigation of tumor operation puncture. The changes of the electrolyte parameters collected by a biological impedance analyzer, an impedance self-adaptive module adjusts input pulse parameters in time, and adaptive high voltage and steep pulse are kept to achieve a maximum tumor destruction effect; and the ablation effect is very ideal.

Description

technical field [0001] The invention relates to an electric pulse ablation device and a simulation method applicable thereto, belonging to the technical field of electric pulse devices. Background technique [0002] Nanosecond pulse treatment of tumor technology is a non-thermal / cold ablation technology, which uses high-voltage nanosecond pulses to act on the internal structure of tumor cells, causing functional changes in the cells, and triggering natural cell apoptosis through cell membrane perforation; inducing tumor apoptosis while not It will cause thermal damage to surrounding normal tissues or blood vessels near the tumor, neurovascular bundles, urethra, rectum, nerves, etc. [0003] However, the existing ablation equipment has the following disadvantages: [0004] First, the puncture strength of the existing electric pulse ablation equipment is difficult to control during the puncture process, so it is usually easy to puncture or damage key tissues or membrane walls...

AI Technical Summary

Problems solved by technology

[0004] First, the existing electric pulse ablation equipment is difficult to control the puncture force during the surgical puncture process, so it is usually easy to puncture or damage key tissues or membrane walls

[0005] Second, in the process of the existing electric pulse ablation, due to the impedance of the tumor tissue, the electrolyte parameters of the tissue exudate in the ablation area change with the ablation time, and the changed electrolyte parameters no longer match the initial electric pulse ablation parameters, resulting in ablation not effectively

[0006] Furthermore, the pulse parameters of the electric pulse ablation equipment, the distance between the two-needle electrodes, the length of the electrode working part and other parameters will affect the electric field coverage of the tumor and the field strength distribution during high-voltage nanosecond pulse therapy, which in turn will affect the effect of pulse ablation therapy

[0007] Because tumors vary from person to person, and the location of the tumor is variable, the shape and size of the tumor are different, and the doctor needs to set multiple parameters such as pulse parameters, double-needle electrode spacing, and the length of the electrode working part. It is difficult to set a reasonable value based on the doctor's own experience , Effective parameter values; even experienced doctors need to spend a lot of time to debug and demonstrate, time-consuming and laborious, and it is difficult to ensure that the settings are reasonable and effective every time

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