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Application of lycium polysaccharides to preparation of drugs for treating hyperlipidemia, hypertension and hyperglycemia

A technology of glycopeptide and wolfberry, which is applied in the application field of wolfberry glycopeptide in the preparation of drugs for the treatment of three highs, can solve the problems of destroying the normal function of organs, nutritional imbalance, and large side effects, and achieves the principle of safe lipid-lowering, blood pressure regulation, and promotion of blood pressure. The effect of insulin secretion

Inactive Publication Date: 2019-11-08
宁夏天仁枸杞生物科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is a "rich man's disease" derived from modern society. At present, the conventional treatment of "three highs" is drug therapy, such as lovastatin, fenofibrate, niacin, cholestyramine, etc. for the treatment of "hyperlipidemia"; Although there are many different types of lipid-lowering drugs, the side effects are relatively large. More patients adopt diet to achieve the goal of weight control. However, this treatment method can easily cause nutritional imbalance and destroy the normal functions of all organs in the body. is an extremely inadvisable treatment
There are also medical institutions that use extracorporeal blood washing to remove blood lipids. Although the effect is obvious, it is dangerous, susceptible to infection, and expensive, so patients will not easily accept this operation
[0003] There are a wide variety of antihypertensive drugs, which can be roughly classified into five categories: diuretics, β-blockers, calcium channel blockers (CCB), angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptors. antihypertensive drugs have different effects and mechanisms, and the effects vary widely, but there is no single drug that can cure the disease at all, and all of them have obvious side effects

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  • Application of lycium polysaccharides to preparation of drugs for treating hyperlipidemia, hypertension and hyperglycemia
  • Application of lycium polysaccharides to preparation of drugs for treating hyperlipidemia, hypertension and hyperglycemia
  • Application of lycium polysaccharides to preparation of drugs for treating hyperlipidemia, hypertension and hyperglycemia

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Embodiment Construction

[0017] Below in conjunction with the accompanying drawings and various experiments, the specific implementation of the present invention will be further described in detail. The following experiments are used to illustrate the present invention, but not to limit the scope of the present invention. The components, structures, mechanisms, etc. involved in the following experiments are all commercially available products unless otherwise specified.

[0018] Experiment 1: Cell experiments on the hypoglycemic effect of Lycium barbarum glycopeptide

[0019] 1. Materials and methods

[0020] 1.1 Materials

[0021] The experimental subjects were mice, and the mouse NIT-L islet β cells were provided by the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences; LBGP was provided by the Lycium Institute of Ningxia Academy of Agricultural Sciences, with a purity of 31.9%. The R-P used in the experiment -MI1640 dry powder medium and trypsin were provided by American G...

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Abstract

The invention relates to the field of pharmaceuticals and health care products, in particular to application of lycium polysaccharides to preparation of drugs for treating hyperlipidemia, hypertensionand hyperglycemia, and aims to provide traditional Chinese medicine tablets, particles or suspension particles, pills, powder or capsules prepared from lycium polysaccharides and pharmaceutically acceptable auxiliary materials or auxiliary ingredients in a mixed mode so as to obtain drugs for treating hyperlipidemia, hypertension and hyperglycemia for realizing the purpose of treating hyperlipidemia, hypertension and hyperglycemia. Meanwhile, it is found that through the lycium polysaccharides, plaques can also be shrunk, thrombus can also be dissolved, vascular endothelial cells are activated and protected, vascular elasticity is improved and increased, and thus the blood pressure and the blood fat are adjusted and controlled comprehensively and effectively, so that blood is clear and pure, blood flows smoothly, vasoconstriction is free, the blood pressure is stable, and thus a series of cardiovascular and cerebrovascular diseases are prevented effectively. It is proved that throughpharmacological properties of the lycium polysaccharides, the blood pressure, the blood fat and the blood glucose can be reduced, the importance of the lycium polysaccharides in treatment of hyperlipidemia, hypertension and hyperglycemia is highly prompted, and the significant efficacy is achieved.

Description

technical field [0001] The invention belongs to the field of medicines and health care products, and in particular relates to the application of wolfberry glycopeptides in the preparation of medicines for treating three highs. Background technique [0002] "Three highs" refers to hypertension, hyperglycemia (diabetes) and hyperlipidemia. It is a "rich man's disease" derived from modern society. At present, the conventional treatment of "three highs" is drug therapy, such as lovastatin, fenofibrate, niacin, cholestyramine, etc. for the treatment of "hyperlipidemia"; Although there are many different types of lipid-lowering drugs, the side effects are relatively large. More patients adopt diet to achieve the goal of weight control. However, this treatment method can easily cause nutritional imbalance and destroy the normal functions of all organs in the body. It is an extremely undesirable treatment method. There are also medical institutions that use extracorporeal blood wa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/14A61P9/12A61P3/10A61P3/06A23L33/18
CPCA61K38/14A61P9/12A61P3/10A61P3/06A23L33/18A23V2002/00A23V2200/326A23V2200/3262A23V2200/328
Inventor 于哲雄
Owner 宁夏天仁枸杞生物科技股份有限公司
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