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Natural composition capable of improving liver function and preventing osteoporosis and preparation method of natural composition

A technology for osteoporosis and liver function, applied in drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as osteoporosis and major adverse reactions that have not been considered, and achieve liver protection and inhibition Hepatic fibrosis, improvement of hepatic steatosis, and improvement of liver function

Inactive Publication Date: 2019-09-17
EZHOU INST OF IND TECH HUAZHONG UNIV OF SCI & TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Drugs such as estrogen, bisphosphonates and calcitonin have good clinical efficacy, but long-term use has relatively large adverse reactions
Clinically commonly used traditional Chinese medicine preparations include Jinkuishenqi Pills, Gushukang Capsules, Zhibai Dihuang Pills, Xianling Gubao Capsules, Liuwei Dihuang Pills, and Qianggu Capsules. Rhizoma Rhizoma Rhizoma Rhizome, Chinese Yam, Cornus officinalis, Salvia Miltiorrhiza and Lycium barbarum, etc., but most of these products only consider to solve the symptoms of osteoporosis, but not the cause of osteoporosis; Other factors were not considered

Method used

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  • Natural composition capable of improving liver function and preventing osteoporosis and preparation method of natural composition
  • Natural composition capable of improving liver function and preventing osteoporosis and preparation method of natural composition
  • Natural composition capable of improving liver function and preventing osteoporosis and preparation method of natural composition

Examples

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Effect test

Embodiment 1

[0038] This embodiment provides a natural composition that can improve liver function and prevent osteoporosis. The raw materials include: 20% of Bupleurum extract, 15% of Angelica extract, 20% of Radix Root extract, and dried tangerine peel. 15% extract, 5% gardenia extract, 15% maca extract and 10% licorice extract.

[0039] The content of saikosaponin in the Bupleurum extract is ≥100mg / g, and the preparation method is as follows:

[0040] Take an appropriate amount of dried Bupleurum, mix it with water in a mass-volume ratio of 1:9, reflux and extract at 45°C for 4 hours, and concentrate the water extract into a paste under reduced pressure, dissolve it with 60% ethanol, and concentrate and dry under reduced pressure to obtain Chai Hu extract.

[0041] The angelica polysaccharide content in the angelica extract is ≥200 mg / g, and the preparation method is:

[0042] Take an appropriate amount of dried Angelica sinensis, crush it, mix it with distilled water at a mass-volume ratio of...

Embodiment 2

[0055] This embodiment provides a natural composition that can improve liver function and prevent osteoporosis. The raw materials include: in weight percentage, Bupleurum vulgaris extract 10%, Angelica sinensis extract 20%, Cyperus rotundus extract 20%, dried tangerine peel 15% extract, 5% gardenia extract, 10% maca extract and 5% licorice extract. The preparation method is basically the same as in Example 1.

Embodiment 3

[0057] This embodiment provides a natural composition that can improve liver function and prevent osteoporosis. The raw materials include: 20% of Bupleurum extract, 10% of Angelica extract, 15% of Radix Root extract, and dried tangerine peel. Extract 10%, Gardenia extract 15%, Maca extract 15%, and Licorice extract 15%. The preparation method is basically the same as in Example 1.

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Abstract

The invention provides a natural composition capable of improving liver function and preventing osteoporosis. The natural composition consists of a radix bupleuri extract, a radix angelica sinensis extract, a nutgrass galingale rhizome extract, a dried orange peel extract, a fructus gardeniae extract, a maca extract and a licorice root extract, the effective components of the components interact, and can restrain rising of serum globulin, alanine aminotransferase and aspartic transaminase (AST) and reduction of albumin, the liver function can be improved, the content of bone minerals of bone density, bone calcium, bone phosphorus and the like can be increased, and the effect of relieving osteoporosis can be achieved.

Description

Technical field [0001] The invention belongs to the technical field of natural compositions, and specifically relates to a natural composition that can improve liver function and prevent osteoporosis and a preparation method thereof. Background technique [0002] Osteoporosis (OP) is a systemic bone disease characterized by low bone mass, damage to the microstructure of bone tissue, and easy fracture. Osteoporosis can occur at any age, but it is more common in postmenopausal women and elderly men. It is estimated that there are nearly 70 million osteoporosis patients in my country and more than 200 million patients with osteopenia. Osteoporotic fractures are extremely harmful and are one of the main causes of disability and death in elderly patients. Moreover, the medical and nursing care of osteoporosis and fractures requires a lot of manpower, material and financial resources, causing a heavy family and social burden. It is predicted that my country’s medical expenses for maj...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61P1/16A61P19/10
CPCA61K36/232A61K36/233A61K36/31A61K36/484A61K36/744A61K36/752A61K36/8905A61K2236/33A61K2236/331A61K2236/51A61K2236/53A61P1/16A61P19/10A61K2300/00
Inventor 余龙江刘浩陈晶晶李东张稀雯金文闻
Owner EZHOU INST OF IND TECH HUAZHONG UNIV OF SCI & TECH
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