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A kind of Chinese herbal medicine composition for treating constipation and preparation method of gel patch thereof

A Chinese herbal medicine composition and a technology for treating constipation, applied in the field of medicine, can solve the problems of damaging the yang energy of the spleen and stomach, weakening the function of the spleen and stomach, and protracted disease, so as to enhance the digestive function of the spleen and stomach, high absorption efficiency, and promote intestinal mucus secretion Effect

Active Publication Date: 2021-08-24
XIAN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present invention is to provide a Chinese herbal medicine composition for treating constipation, which solves the problem of traditionally using cold and cool laxatives such as rhubarb, senna, and aloe to treat constipation, which further damages the yang energy of the spleen and stomach, weakens the function of the spleen and stomach, and then aggravates constipation. and problems that cause disease to persist

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] A preparation method of a gel patch of a Chinese herbal medicine composition for treating constipation, comprising the following steps:

[0061] Step 1: Weigh 8.553% Atractylodes Rhizoma Atractylodes Rhizome, 6.579% Rhodiola Rosea, 3.873% Fructus Citrifolia, 13.725% Radish Seed (mashed), 6.579% Angelica Sinensis, 14.706% Rehmannia Root, 14.706% Scrophulariaceae Scrophulariae, 8.553% mulberry fruit, 8.553% psoraleae (mashed) and 14.173% Caulis japonica, the sum of the mass percentages of the above components is 100%, the coarse powder of the above medicinal materials is pulverized and mixed, and added 8 times the amount of 85% ethanol, soak for 30 minutes, reflux extraction 3 times, 60 minutes each time, combine the 3 extracts, recover the ethanol under reduced pressure until there is no alcohol smell, and obtain medicinal material extract, refrigerate, and set aside.

[0062] Step 2: Weigh 0.498% sodium polyacrylate ViscomateNP-800, 0.498% sodium polyacrylate ViscomateN...

Embodiment 2

[0072] Step 1: Weigh 10.236% Atractylodes Rhizoma Atractylodes Rhizome, 11.811% Rhodiola Rosea, 3.150% Fructus Citrifolia, 11.024% Radish Seed (mashed), 7.874% Angelica, 7.874% Rehmannia glutinosa, 11.811% Scrophulariaceae Scrophulariae, 11.811% mulberry fruit, 14.173% psoraleae (mashed) and 10.236% Caulis japonica, the sum of the mass percentages of the above components is 100%, and the coarse powder of the above medicinal materials is pulverized and mixed, and added 10 times the amount of 75% ethanol, soak for 30 minutes, reflux extraction 3 times, 60 minutes each time, combine the 3 extracts, recover the ethanol under reduced pressure until there is no alcohol smell, obtain medicinal material extract, refrigerate, and set aside.

[0073] Step 2: Weigh 0.579% sodium polyacrylate ViscomateNP-800, 1.353% sodium polyacrylate ViscomateNP-700, 0.169% aluminum glycinate, 0.058% disodium edetate, and 2.415% kaolin according to mass percentage , 28.983% of glycerin, 3.864% of polyvi...

Embodiment 3

[0082] Step 1: Weigh 14.173% Atractylodes Rhizoma Atractylodes Rhizome, 7.874% Rhodiola Rosea, 7.087% Fructus Citrifolia, 7.087% Radish Seed (mashed), 11.811% Angelica Sinensis, 11.811% Rehmannia Root, 7.874% Scrophulariaceae Scrophulariae, 7.874% mulberry fruit, 10.236% psoraleae (mashed) and 14.173% jasmine vine, the sum of the mass percentages of each component is 100%, after the above-mentioned medicinal material coarse powder is crushed and mixed, add 8 Double the amount of 85% ethanol, soak for 30 minutes, reflux extraction 3 times, 60 minutes each time, combine the 3 extracts, recover the ethanol under reduced pressure until there is no alcohol smell, and obtain medicinal material extract, refrigerate, and set aside.

[0083] Step 2: Weigh 1.205% sodium polyacrylate ViscomateNP-800, 0.516% sodium polyacrylate ViscomateNP-700, 0.194% aluminum glycinate, 0.065% disodium edetate, and 2.582% kaolin according to mass percentage , 30.127% of glycerin, 4.304% of polyvinylpyrro...

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Abstract

The invention discloses a Chinese herbal medicine composition for treating constipation, which is composed of the following components according to the mass percentage: 8.553-17.647% Atractylodes macrocephala, 6.579-14.706% Rhodiola rosea, 2.632-8.824% Citrus aurantium, 5.921-13.725% radish seed, 6.579-14.706% angelica, 6.579-14.706% rehmannia, 6.579-14.706% crocus, 6.579-14.706% mulberry, 8.553-17.647% psoralen and 8.553-17.647% vine , the sum of the mass percentages of the above components is 100%; a preparation method of the gel patch of the above-mentioned Chinese herbal medicine composition is also disclosed. It is prepared by extracting medicinal materials, mixing with pharmaceutical excipients for preparing patches, coating with a covering film, cutting and forming, cross-linking and curing, and packaging.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a Chinese herbal medicine composition for treating constipation, and also relates to a preparation method of a gel patch of the Chinese herbal medicine composition. Background technique [0002] In the current society, due to factors such as diet structure, living habits such as significantly reduced exercise, increased work and study pressure, anxiety and depression, and long-term chemotherapy for cancer patients, the number of patients with constipation has increased sharply, and it occurs in all age groups. Especially after the age of 50, the prevalence of constipation increases significantly with age; after the age of 70, the incidence of constipation is more common. Constipation has brought greater harm to patients, such as: (1) dry and hard stools, difficult and painful defecation, which can easily cause anal fissures and blood in the stool. Further aggravate ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/808A61K9/70A61K47/32A61K47/10A61P1/10
CPCA61K9/7023A61K36/232A61K36/284A61K36/31A61K36/41A61K36/487A61K36/605A61K36/74A61K36/752A61K36/804A61K36/808A61K47/10A61K47/32A61K2236/333A61K2236/39A61P1/10A61K2300/00
Inventor 李伟泽韩文霞赵宁孙艳平何树苗王之炜杨黎彬张寒付丽娜关丽
Owner XIAN MEDICAL UNIV
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