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Anti-alcoholic liver-protecting agent and preparation method thereof

A technology of anti-alcohol and liver-protecting tablet, which is applied in the field of anti-alcohol and liver-protecting agent and its preparation, and can solve the problems of no antiemesis, liver protection, refreshing effect, accelerated ethanol catabolism, poor ethanol catabolism, etc. , to achieve the effect of preventing gastric ulcer or bleeding, protecting the liver, and reducing the burden of digestion

Active Publication Date: 2021-05-28
湖南省中医药研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The patent application number is 200410060450.6 provides a hangover granule, which is composed of longevity fruit, longevity leaf, adzuki bean flower, orange peel, mangosteen flower, and red date. Its main disadvantage is that it has no anti-vomiting, liver-protecting, and refreshing effects, and promotes ethanol decomposition. The metabolism is poor, and there is no focus on one target - hangover and alleviating the symptoms of drunkenness, so the effect is poor
[0004] The patent application No. 200510045004.2 provides a Chinese medicine for hangover, which is composed of kudzu flower, Hovenia dulcis, kudzu root, betel nut, red cardamom, orange red, amomum, cardamom, dendrobium, privet lucidum, and licorice. Drunkenness and relieve symptoms of drunkenness, and protect human health. The main disadvantage is that there are many spicy and fragrant medicines in the prescription, such as jujube betel nut, red cardamom, orange red, amomum, grass cardamom, which are easy to consume qi and hurt yin, and make people dry throat and tongue Dryness, there are yin-nourishing medicines Dendrobium and Ligustrum lucidum in the prescription, which seek the same gas, and are easy to stick to wine wetness, affecting the catabolism of alcohol, which is not conducive to hangover, so the effect is poor
[0005] The patent application number 200510017503.0 provides a method for making hangover capsules, which consists of 15-25g of licorice, 15-25g of kudzu flower, 15-25g of kudzu root, 15-25g of amomum, 15-25g of galangal, and 10-20g of white peony , peppermint 10-20g, cassia seed 10-20g, first make the medicinal liquid according to the decoction method of traditional Chinese medicine, and then set aside, put the medicinal liquid in a three-effect vacuum high-energy evaporation concentrator, depressurize, heat to 80 ℃ and concentrate into Thick liquid or paste is placed in a drying oven, heated to 60°C, dried at a constant temperature for 4 hours, crushed, sieved, filled into capsules, sterilized, and made into a finished product. The main disadvantage is that Amomum amomi is not extracted in the process. The volatile oils in medicines such as galangal and peppermint cause a serious loss of active ingredients. In addition, cassia seeds contain anthraquinone glycosides, which can cause adverse reactions such as diarrhea. Women who drink cassia seeds for a long time can cause irregular menstruation, and in severe cases, endometrium can cause irregular menstruation. normal
[0006] The patent application No. 200610047699.2 provides an anti-alcoholic and liver-protecting agent, which is prepared by extracting Hovenia dulcis, Pueraria japonica, L-cysteine, calcium gluconate, calcium pantothenate, taurine, honey, etc. , the medicine tastes good, and the effect of hangover is very obvious, but its main disadvantage is that the composition of the prescription is guided by the compatibility theory of traditional Chinese medicine prescriptions. symptom

Method used

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  • Anti-alcoholic liver-protecting agent and preparation method thereof
  • Anti-alcoholic liver-protecting agent and preparation method thereof
  • Anti-alcoholic liver-protecting agent and preparation method thereof

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preparation example Construction

[0035] The second aspect of the present invention provides a preparation method of anti-alcoholic and liver-protecting agent, comprising the following steps:

[0036] (1) After mixing Cinnamomum camphora with water, distill and extract volatile oil until the volatile oil no longer increases, obtain Cinnamomum camphora volatile oil for subsequent use, collect Cinnamomum camphora medicinal liquid after distillation for subsequent use, and collect Cinnamomum camphora medicine residue for subsequent use;

[0037] (2) Pass 80-100 mesh sieve after pulverizing basil, obtain basil fine powder and basil coarse slag for subsequent use;

[0038] (3) Pueraria japonica, Hovenia dulcis, Cranium japonica, Chuanketong, sour soaked root, maple ball, camphor tree medicinal residue obtained in step (1), white and coarse residue obtained in step (2) and water Mix, decoct and extract 1-3 times, filter, combine the filtrates to obtain the water extract;

[0039] (4) mixing the Cinnamomum camphora ...

Embodiment 1

[0049] (1) After mixing 0.8kg of Cinnamomum camphora with 6.4kg of water, extract volatile oil by distillation until the volatile oil no longer increases, obtain C. camphora volatile oil for subsequent use, collect C.

[0050] (2) Cross 80 mesh sieves after 0.8kg white powder is pulverized, obtain particle and pass through 80 mesh white and fine powder and particle fail to pass 80 mesh white and coarse slag for subsequent use;

[0051] (3) 1kg kudzu flower, 1kg hovenia dulcis, 1kg chamomile, 0.8kg Chuankeke, 1kg sour soaked root, 0.6kg maple ball, the camphor tree medicinal residue obtained in step (1), step (2) After mixing the obtained white and coarse residue, add 10 times the amount of water of the total amount of the mixture, soak for 45 minutes, boil with strong fire, then decoct with slow fire for 90 minutes, filter and collect the filtrate for later use; add 8 times the amount of water of the above mixture to the filter residue, soak After 45 minutes, boil with strong ...

Embodiment 2

[0055] (1) After mixing 1.2kg Cinnamomum camphora with 12kg water, distillation extracts volatile oil, until volatile oil no longer increases, obtain Cinnamomum camphora volatile oil for subsequent use, collect Cinnamomum camphora medicinal liquid after distillation for subsequent use, Cinnamomum camphora medicine residue for subsequent use;

[0056] (2) Pass 1kg white powder through a 100-mesh sieve after being pulverized, and obtain white powder and fine powder and particles that fail to pass through 100 mesh white and coarse slag for subsequent use;

[0057] (3) 1.5kg kudzu flower, 1.5kg hovenia dulcis, 1.5kg chamomile, 1.2kg Chuanketong, 1.5kg sour soaked root, 1kg maple ball, the camphor tree medicinal residue obtained in step (1), step (2) After mixing the white and coarse slag obtained, add 10 times the amount of water of the total amount of the mixture, soak for 30 minutes, boil with strong fire and decoct with slow fire for 60 minutes, filter and collect the filtrate f...

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Abstract

The invention relates to the technical field of traditional Chinese medicines, and discloses an anti-alcohol and liver-protecting agent and a preparation method thereof. The anti-alcoholic and liver-protecting agent is prepared from the following raw material components in parts by mass: 5-15 parts of kudzu flower, 5-15 parts of Hovenia dulcis, 4-12 parts of camphor seed, 5-15 parts of Huangcao, Baiji 5‑10 parts, Chuan Mutong 4‑12 parts, sour bubble root 5‑15 parts, maple ball 3‑10 parts, the overall compatibility of this anti-alcohol and liver protection agent is generally compared with kudzu flower and Hovenia dulcis The formula of the main drug has better anti-alcoholic and liver-protecting effects, and the time for hangover and sobering up is shorter. When taken before drinking, the effective time is faster. Antiemesis, liver protection, can enhance the activity of alcohol dehydrogenase and acetaldehyde dehydrogenase in human liver, and accelerate the catabolism of ethanol.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to an anti-alcohol and liver-protecting agent and a preparation method thereof. Background technique [0002] The liver is the central hub of carbohydrate metabolism, lipid metabolism and protein metabolism in the human body, and has important functions such as detoxification and bile secretion. After the human body drinks alcohol, the alcohol is mainly absorbed through the duodenum, and about 90% of the alcohol is metabolized in the liver. Alcoholism, commonly known as drunkenness, refers to the abnormal state of body function that occurs after heavy drinking. It mainly damages the nervous system, liver and stomach. Therefore, taking liver-protecting drugs before or after drinking alcohol has a certain effect on hangover. [0003] The patent application number is 200410060450.6 provides a hangover granule, which is composed of longevity fruit, longevity leaf,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/898A61P39/02A61P1/16
CPCA61K36/185A61K36/488A61K36/54A61K36/716A61K36/72A61K36/73A61K36/898A61K2236/331A61K2236/39A61P1/16A61P39/02A61K2300/00
Inventor 刘瑞连吴玉华蒋孟良李鑫李卓达
Owner 湖南省中医药研究院
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