Composition capable of removing acne and fading scars

A composition, a technology for lightening scars, applied in the directions of drug combinations, preparations for skin care, cosmetics, etc., can solve the problems of unsatisfactory acne removal effect, long cycle, unreachable acne, etc., achieve the best antibacterial effect, reduce irritation Sex, improve the effect of hair follicle keratinization

Active Publication Date: 2019-08-02
广州睿晞生化科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, due to the limitations of the formulations of commercially available skin care products, they can only alleviate symptoms to a certain extent, and the effect of acne removal is not ideal, and the cycle is long, and it is impossible to achieve the desired effect on more serious acne.

Method used

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  • Composition capable of removing acne and fading scars
  • Composition capable of removing acne and fading scars

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～5 and comparative example 1～4

[0018] See Table 1 for the formulations of the compositions described in Examples 1-5 and Comparative Examples 1-4 that can remove acne scars.

[0019] Compositions that can remove acne scars described in Table 1 Examples 1-5 and Comparative Examples 1-4

[0020]

Embodiment 6

[0022] In order to verify the antibacterial effect of the composition of the present invention that can remove acne light marks, refer to GB15979-2002 "Hygienic Standards for Disposable Sanitary Products" Appendix C 4 "Bacteriostatic Performance Test Method for Dissolution Antibacterial (Inhibition) Products "The antibacterial properties of the compositions described in Examples 1 to 5 of the present invention and Comparative Examples 1 to 4 that can remove acne scars are measured: (1) Preparation of bacterial suspension: take 24h culture of Propionibacterium acnes with 0.03mol Wash with / L phosphate buffer to make 104~106CFU / mL bacterial suspension; (2) Take 1g of the tested sample respectively, add 0.1mL of the above bacterial suspension to coat and mix evenly, start timing, add 9mL after 20min. .03mol / L phosphate buffer solution was mixed thoroughly, and after proper dilution, 3 dilutions were taken, and 1mL was placed in two parallel plates, and then the corresponding mediu...

Embodiment 7

[0030] The compositions described in Examples 1 to 5 and Comparative Examples 1 to 4 that can remove acne scars are made into a gel according to the following formula: 36% of the composition that can remove acne scars, 3% glycerin, 3% propylene glycol, transparent 0.5% hyaluronic acid, 0.3% carbomer, 0.1% disodium edetate, 0.8% citric acid and the rest deionized water.

[0031] In order to further illustrate the effect of the composition of the present invention, choose 45 mild or moderate acne patients (with reference to PillSburv and the International Improved Acne Powder Method for diagnosis of mild acne patients), including 26 males and 19 females aged between Between the ages of 18 and 30, the course of disease is 1 to 3 years, and the exclusion criteria of volunteers meet the inclusion and exclusion criteria of "Diagnostic Criteria and Treatment Principles of Cosmetic Contact Dermatitis". Divided into 9 groups on average, with 5 people in each group, each group of volunt...

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Abstract

The invention discloses a composition capable of removing acne and fading scars. The composition is prepared from a salvia miltiorrhiza root extract, a clove bud extract, a scutellaria baicalensis extract, papain, aloe barbadensis leaf meal, asiaticoside, dipotassium glycyrrhizinate and o-cymene-5-ol. According to the composition disclosed by the invention, the clove bud extract and the papain arematched together to promote transdermal absorption of plant acne-removing repairing agents (the salvia miltiorrhiza root extract, the scutellaria baicalensis extract, the aloe barbadensis leaf meal and the asiaticoside); the dipotassium glycyrrhizinate and the o-cymene-5-ol are also added into the composition in addition to plant ingredients, and can be compounded with the plant ingredients, so that on one hand, the irritation of chemicals is reduced; on the other hand, the inhibitory effect on bacteria causing the acne can be improved, and a better antibacterial effect is achieved. In addition, pores can be cleared; the growth of pathogenic bacteria groups in hair follicles can be inhibited; follicular cornification can be improved. The invention further provides a skin care product containing the composition capable of removing the acne and fading the scars.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a composition capable of removing acne scars. Background technique [0002] Acne is a common skin problem. Acne is a skin disease caused by blockage of hair follicles and sebaceous glands and inflammation of pilosebaceous glands. The sebaceous glands mostly open at the hair follicle opening. Once the hair follicle opening is blocked, excessive sebum metabolism will produce excessive fatty acid stimulation and the effect of excessive proliferation of Propionibacterium acnes in a closed environment, causing an inflammatory response in the skin, and Propionibacterium acnes produces The lipase decomposes sebum to generate free fatty acids, and at the same time chemoattracts inflammatory cells and mediators, and finally induces and aggravates the inflammatory response. Therefore, the manifestations of acne are whiteheads and blackheads, inflammatory papules and pustules, cysts and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/9789A61K8/66A61K8/63A61K8/60A61K8/34A61P17/02A61P17/10A61Q17/00A61Q19/00
CPCA61K8/347A61K8/602A61K8/63A61K8/66A61Q17/005A61Q19/00A61K8/9789A61K8/9794A61P17/02A61P17/10
Inventor 吴文基
Owner 广州睿晞生化科技有限公司
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