Real-time Noise Reduction Enhancement Method for Ultraviolet Raman Spectroscopy System

A spectroscopic system, UV Raman technology, applied in the field of noise reduction and enhancement of UV Raman spectroscopic system, can solve the problem of reducing real-time Raman spectrum

Active Publication Date: 2020-11-13
BEIJING INSTITUTE OF TECHNOLOGYGY
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] The technical problem to be solved by the real-time noise reduction and enhancement method of the ultraviolet Raman spectroscopy system disclosed by the present invention is: reduce the random noise of the real-time Raman spectroscopy, enhance the Raman characteristic peak, and realize the Raman spectroscopy detection system with low Raman signal-to-noise ratio Optimization of acquired real-time spectra

Method used

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  • Real-time Noise Reduction Enhancement Method for Ultraviolet Raman Spectroscopy System
  • Real-time Noise Reduction Enhancement Method for Ultraviolet Raman Spectroscopy System
  • Real-time Noise Reduction Enhancement Method for Ultraviolet Raman Spectroscopy System

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Embodiment 1

[0060] At present, the portable 266nm laser-excited Raman spectroscopy system developed by the laboratory is used to carry out Raman detection on Heroin samples. The acquisition integration time is 2 seconds, and N = 9 is selected, that is, when the computer receives a new frame of spectrum, the first 9 frames of spectrum are temporarily stored, and the X axis is Raman shift. After the samples are stably placed for 6 seconds, the real-time noise reduction and enhancement processing of the ultraviolet Raman spectroscopy system begins. The real-time noise reduction and enhancement processing flow of the ultraviolet Raman spectroscopy system is shown in Figure 1.

[0061] The embodiment discloses a real-time noise reduction and enhancement method for an ultraviolet Raman spectroscopy system, which comprises the following specific steps:

[0062] Step 1, as shown in figure 2, collect that ultraviolet Raman signal of heroin samples in real time, and make statistic on the collected Rama...

Embodiment 2

[0073] The real-time ultraviolet Raman detection signals of acetaminophen tablets and cefixime dispersible tablets are processed by using the real-time noise reduction enhancement method of the ultraviolet Raman spectroscopy system of this patent, and the acquisition method and conditions of the real-time ultraviolet Raman signals are the same as those of Embodiment 1. When the patented real-time noise reduction enhancement method of ultraviolet Raman spectroscopy system is applied to acetaminophen tablets, the absolute value threshold of the slope at the left end of the interval selected in step 1 is 50, the threshold of the ratio of standard deviation to average value in step 2 is 0.02, the initial value of sigma_r in step 3 is 0.04, Smin is 0.01, and the threshold of the ratio of standard deviation to average value in each noise area of the filtered image is 0.005. When the patented real-time noise reduction enhancement method of ultraviolet Raman spectroscopy system is applied...

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Abstract

The invention discloses a real-time noise reduction and enhancement method for an ultraviolet Raman spectrum system, which belongs to the field of spectrum detection and spectrum processing technology and signal processing. The invention collects ultraviolet Raman signals in real time, performs statistics on collected Raman signal data, and predicts effective peak values ​​of Raman signals, and the effective peak values ​​include effective troughs and peaks. Each frame of Raman spectrum collected is processed, and for each frame of Raman spectrum, each frame of Raman spectrum is divided into various regions through the obtained effective trough, and the properties of each segmented region are judged separately , the area attribute refers to the noise area attribute or the effective Raman signal area attribute, the noise area is filtered, and then the Raman signal area and the filtered noise area are combined. Afterwards, the processed N+1 frame spectra are spliced ​​into a 2D image along the time axis, and the 2D image is filtered through an iterative bilateral filtering method. After filtering, the N+1 spectra are superimposed and normalized along the time axis. Obtain the denoised Raman spectrum.

Description

Technical field [0001] The invention relate to a noise reduction and enhancement method of an ultraviolet Raman spectrum system, in particular to a method for reducing spectral random noise of real-time ultraviolet Raman signal and improving signal-to-noise ratio so as to enhance Raman peak signals, belonging to that field of spectral detection and spectral processing technology and signal processing. technical background [0002] Raman spectroscopy is a nondestructive spectral detection method based on inelastic light scattering (that is, the energy / frequency of incident laser changes) of the interaction between laser and matter. By measuring the specific Raman spectrum (i.e., Raman fingerprint) of the molecular system to be measured, the sample can be quickly, simply and repeatedly tested in a non-contact and quantitative way, which has the characteristics of short time, small sample consumption and accurate measurement results. But the sensitivity of Raman spectrum detection i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06K9/00
CPCG06F2218/04G06F2218/08G06F2218/12
Inventor 金伟其郭一新何玉青赵曼
Owner BEIJING INSTITUTE OF TECHNOLOGYGY
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