Traditional Chinese medicine composition with effect of inhibiting activity of monoamine oxidase A and application thereof
A technology of monoamine oxidase and composition, which is applied in the direction of drug combination, medical preparation containing active ingredients, pharmaceutical formula, etc., to achieve a significant synergistic effect
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Embodiment 1
[0023] The medicinal material of Rhizoma Chuanxiong was taken, crushed, and passed through a 100-mesh sieve; the medicinal material of Angelica sinensis was obtained, crushed, and passed through a 100-mesh sieve; the Rhizoma Chuanxiong powder and the Angelica sinensis powder were mixed according to the mass ratio of 1:2, and packaged separately to obtain a monoamine oxidase A inhibitor.
Embodiment 2
[0025] Take the medicinal material of Chuanxiong, crush it, add 8 times the amount of 70% ethanol, soak overnight, heat and reflux for extraction 3 times, combine the filtrate, recover the alcohol, concentrate, and dry to obtain the ethanol solution extract of Rhizoma Chuanxiong; take the medicinal material of Angelica sinensis, crush it, add 8 times Measure 70% ethanol, soak overnight, heat and reflux to extract 3 times, combine the filtrate, recover alcohol, concentrate, dry, and obtain the ethanol solution extract of Angelica sinensis; :0.2 Mixed evenly to obtain monoamine oxidase A inhibitor, the mass content of ferulic acid is 1.24%, and the mass content of ligustilide is 16.1%.
Embodiment 3
[0027] Ligusticum chuanxiong medicinal material was taken, crushed, added 8 times the amount of distilled water, soaked overnight, extracted by heating, and the volatile oil was collected by condensation to obtain volatile oil of chuanxiong; the extract product of angelica sinensis was purchased in the market, and the volatile oil of angelica sinensis was obtained by water distillation. The volatile oil of Rhizoma Chuanxiong and the volatile oil of Angelica sinensis were separated and purified by molecular distillation technology, and then mixed uniformly according to the mass ratio of 1:5 to obtain the monoamine oxidase A inhibitor, and the mass content of ligustilide was 8.0%.
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