Highly-efficient moisturizing composition

A composition and high-efficiency technology, applied in the directions of cosmetics, skin care preparations, cosmetic preparations, etc., can solve the problem of not being reported to contain cellular components, and achieve the effect of reducing transdermal water loss and realizing skin moisturization.

Inactive Publication Date: 2019-05-28
辉达生物医药(苏州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As far as it is now known, vernix is ​​unique to humans, although other animals have similar structures, such as the peripheral membrane of rodents, lanolin of sheep, etc., which have similar functions to vernix, but none of these substances have been reported Contains cellular components

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Provides a high-efficiency moisturizing composition composed of squalane, jojoba oil, lecithin, cholesterol, ceramide composition. The content of each component of the high-efficiency moisturizing composition is: by mass percentage, squalane 70.5%, jojoba oil 20%, lecithin 3%, cholesterol 6%, ceramide 0.5%.

[0016] The preparation method of the biomimetic composition comprises the steps of: (1) heating squalane and jojoba oil to 95°C; (2) adding ceramide , Stir to dissolve evenly; (3) Add lecithin and cholesterol, stir to dissolve evenly; (4) Cool to 40°C.

Embodiment 2

[0018] A high-efficiency moisturizing composition is provided, which is composed of squalane, polyglyceryl isostearate, caprylic / capric triglyceride, cholesterol, lecithin, ceramide II, glycosphingolipid, and cholesterol sulfate. The content of each component of the high-efficiency moisturizing composition is: in terms of mass percentage, squalane 60.8%, polyglyceryl isostearate 20%, caprylic acid / capric triglyceride 7%, cholesterol 6%, lecithin 3%, ceramide II 0.5%, glycosphingolipid 2.4%, cholesterol sulfate 0.3%.

[0019] The preparation method of the high-efficiency moisturizing composition comprises the following steps: (1) heating squalane to 95°C; (2) adding the remaining materials one by one, stirring and dissolving evenly; (3) cooling to 40°C.

[0020] Effect experiment: skin water loss test experiment

[0021] Equipment: Tested with Delfin VapoMeter skin moisture tester.

[0022] 10 healthy subjects, aged 20 to 30 years old, with an average of 26.5 years old. The ...

Embodiment 3

[0026] A moisturizing emulsion is provided, which is obtained by combining the high-efficiency moisturizing composition of the present invention with other auxiliary materials. The specific components and contents are: in terms of mass percentage, 77.55% of water, 6.00% of glycerin, and 0.10% of dipotassium glycyrrhizinate , Symsave H 0.50%, Butylene Glycol 3.00%, Hydrolite 6 0.50%, Xanthan Gum 0.15%, Caprylic / Capric Triglyceride 3.00%, Monoglyceride 0.80%, Cetostearyl Alcohol 1.50%, 5.00% of the high-efficiency moisturizing composition described in Example 2, 1.50% of glyceryl stearate citrate Axol C 62 Pellets, and 0.40% of ammonium acryloyldimethyltaurate / VP copolymer.

[0027] The preparation method of the moisturizing emulsion includes: (1) weighing water, glycerin, dipotassium glycyrrhizinate, Symsave H, butanediol, Hydrolite 6, and xanthan gum in a beaker, stirring and heating to 85°C; (2) Weigh caprylic / capric triglyceride, monoglyceride, cetostearyl alcohol, Axol C 62...

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PUM

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Abstract

The present invention discloses a highly-efficient moisturizing composition comprising squalane, a liquid monoester and a lipid at a mass percentage of squalane 50-95%, liquid monoester 3-30%, and lipid 0.1-20%. In the above manner, the highly-efficient moisturizing composition is a fetal fat imitation biomass with the composition and proportion similar to those of human skin lipids, can help skins rebuild barrier function, reduce transdermal water loss, realize moisturization of skins fundamentally, different from moisturizing routes such as glycerin and fats, and further can be used as a composition in cosmetics, skin care, personal care, and pharmaceutical formulations.

Description

technical field [0001] The invention relates to the technical field of daily chemical compositions, in particular to a high-efficiency moisturizing composition. Background technique [0002] Vernix is ​​a layer of natural protective film covering the skin surface of fetuses and newborns. It is composed of free lipids and cell components such as wax esters, sterols, squalene, ceramides, cholesterol, and triglycerides. As far as it is now known, vernix is ​​unique to humans, although other animals have similar structures, such as the peripheral membrane of rodents, lanolin of sheep, etc., which have similar functions to vernix, but none of these substances have been reported Contains cellular components. The composition of vernix is ​​similar to that of skin lipids. In addition, vernix is ​​formed in the last trimester of pregnancy, which is close to the formation time of stratum corneum. Therefore, it is believed that vernix can protect skin with stratum corneum damage and a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/31A61K8/37A61Q19/00
Inventor 谢静红严泽民王天翔
Owner 辉达生物医药(苏州)有限公司
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