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Radix tetrastigme wound healing promoting ointment and preparation method thereof

A wound healing ointment and cloverleaf technology, applied in the medical field, can solve the problems such as the inaccessibility of the wound to the air, the obstruction of air communication, and the unpleasant smell of the liquid band-aid, so as to achieve rapid wound healing, simple processing technology, and inhibition of bacterial growth. Effect

Inactive Publication Date: 2019-05-24
ZHEJIANG SCI-TECH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0022] Ethanol is added to the liquid band-aid described in the above method one, for patients with wounds, it may have irritating pain and poor air permeability
The liquid band-aid described in method two also has the shortcoming of poor air permeability
[0023] To sum up, after the above-mentioned liquid band-aid is applied, it cannot dry quickly, and it hinders the communication with the air, resulting in the wound not being exposed to the air and prone to skin necrosis; when the wound is severe, the liquid is applied and the pain is unbearable (especially the formula contains alcohol. When the wound is infected, the liquid Band-Aid smells bad

Method used

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  • Radix tetrastigme wound healing promoting ointment and preparation method thereof
  • Radix tetrastigme wound healing promoting ointment and preparation method thereof
  • Radix tetrastigme wound healing promoting ointment and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] Embodiment 1, a kind of preparation method of cloverleaf ointment for promoting wound healing, carries out following steps successively:

[0082] 1), dry the root of Clover root until the water content is ≤ 5%, and then pulverize it to pass through a 24-mesh sieve;

[0083] According to the solid-liquid ratio of 1g / 10ml, add deionized water to 500g of the obtained root tuber powder for ultrasonication, power: 600w; frequency: 45KHz, time: 30min; so that the root tuber powder is fully dissolved to obtain a solution.

[0084] 2), the solution is filtered under vacuum conditions (vacuum degree 98kPa), and the obtained filtrate is concentrated to near dryness by a rotary evaporator (evaporating temperature is set to 80° C.) to obtain a trifoliate green extract (extracted from the effective active ingredient of trifoliate green things);

[0085] 3), set formula:

[0086] Clover green wound healing ointment consists of the following components by weight:

[0087] Clover ex...

Embodiment 2～ Embodiment 7

[0092] Embodiment 2~Example 7, change the formula of the cloverleaf ointment promoting wound healing in step 3), and the rest are equal to embodiment 1. The formula is described in Table 3 below

[0093] The formula of table 3, embodiment 1~embodiment 7

[0094]

[0095] The following cloverleaf pharmacology test is carried out to the cloverleaf green promoting wound healing ointment that above-mentioned embodiment 1~embodiment 7 gains:

[0096] Experiment 1. Antibacterial effect of Sanyeqing Wound Healing Ointment

[0097] After the three-leaf green wound healing ointment is mixed with water at a volume ratio of 1:2, the three-leaf green wound healing ointment dilution is obtained.

[0098] Take the uniformly diluted Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Pseudomonas aeruginosa, Staphylococcus epidermidis, and Enterococcus bacteria, and use the diluted coating plate method Evenly inoculate the Staphylococcus aureus bacterial liquid, Escherichia...

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Abstract

The invention discloses a radix tetrastigme wound healing promoting ointment and a preparation method thereof. The preparation method comprises the following steps: crushing radix tetrastigmae root tubers, adding deionized water, carrying out vacuum filtration on the obtained solution, and concentrating filtrate to obtain a radix tetrastigmae extract. The root tuber wound healing promoting ointment consists of the following components in percentages by weight: 10%-15% of a root tuber extract, 0.5%-2% of borneol, 10%-15% of glyceryl monostearate, 15%-20% of stearic acid, 8%-12% of glycerol, 2%-4% of triethanolamine, 0.5% of ethylparaben and the balance of deionized water. The components are mixed to obtain the radix tetrastigme wound healing promoting ointment. The radix tetrastigme wound healing promoting ointment can effectively inhibit bacterial breeding around a wound, thereby achieving effects of diminishing inflammation, resisting bacteria, removing swelling, removing slough and promoting growth of tissue regeneration, and rapidly healing the wound. The radix tetrastigme wound healing promoting ointment is convenient to use.

Description

technical field [0001] The invention belongs to the field of medical technology, and in particular relates to an ointment for promoting wound healing and a preparation method thereof. Background technique [0002] Wound healing refers to the healing process after the body is subjected to external forces, and the skin and other tissues are severed or damaged, including the regeneration of various tissues, the complex combination of granulation tissue hyperplasia, and scar tissue formation, showing the synergy of various processes. The basic process of wound healing: acute inflammation stage→cell proliferation stage→scar formation stage→regeneration of epidermis and other tissues. During the healing process of patients with large wounds caused by body surface surgery or trauma, most of them use surgical needles to repair the wound. The existing pastes are easy to fall off or deform from the wound when the user is active. , The wound is in contact with external bacteria, which...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61K9/06A61P17/02A61P29/00A61K31/045
Inventor 孙延芳陈曦梁宗锁许鑫瀚郭静浦桂雪徐家豪车勇屠仕俊李伯齐穆罕默德·卡西姆昂秀植
Owner ZHEJIANG SCI-TECH UNIV
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