Cosmetic compositions and methods
A technology of composition and extract, which is applied in the direction of cosmetics, cosmetic preparations, drug combinations, etc., and can solve problems such as irritation, greasy feeling, and blemishes
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Embodiment 1
[0086] A formulation having the ingredients in Example 1 was prepared as a topical skin composition according to the present disclosure. The formulations in Tables 1 to 3 provide examples of cosmetic compositions according to the present disclosure.
[0087] Table 1^
[0088] Element
% concentration (by weight)
Evening Primrose (Evening Primrose) Oil
1
0.04
Alpine Rose Rhododendron Extract
0.002
Acetyl Hydroxyproline
0.00001
0.00001
Appropriate amount
[0089] ^ The formulation can be prepared by mixing the ingredients in a beaker with heating at 70 to 75°C until homogeneous. The formulation can then be cooled to standard room temperature (20 to 25°C). Also, if desired, additional ingredients can be added, for example to modify the rheological properties of the composition, or to add skin benefit ingredients.
[0090] * For example ex...
Embodiment 2
[0100] Assays that can be used to determine the efficacy of any one or any combination of ingredients disclosed throughout this specification and in the claims, or compositions having combinations of said ingredients, can be performed by methods known to those of ordinary skill in the art. Make sure. The following are non-limiting assays that can be used in the context of the present disclosure. It should be appreciated that other testing procedures may be used including, for example, objective and subjective procedures.
[0101] Using the following test, the following results were obtained using a composition comprising alpine rosea rhododendron extract, evening primrose (evening primrose) oil, and acetyl hydroxyproline and arginine / lysine polypeptides:
[0102]
[0103] Collagen Stimulation Assay: Collagen is an extracellular matrix protein critical to skin structure. Increased collagen synthesis helps improve skin firmness and elasticity. This bioassay can be used to ...
Embodiment 3
[0108] Embodiment 3 (other analysis)
[0109] Assays that can be used to determine the efficacy of any ingredient or any combination of ingredients disclosed throughout this specification and in the claims, or compositions having said combination of ingredients, can be determined by methods known to those of ordinary skill in the art. The following are non-limiting assays that can be used in the context of the present disclosure. It should be appreciated that other testing procedures may be used including, for example, objective and subjective procedures.
[0110] B16 Pigmentation Analysis: Melanogenesis is the process by which melanocytes produce melanin, the naturally occurring pigment that gives skin, hair, and eyes their color. Inhibiting melanogenesis is beneficial in preventing skin darkening and lightening dark spots associated with ageing. This bioassay uses the immortalized mouse melanoma cell line B16-F1 melanocytes (ATCC) to analyze the effect of compounds on mela...
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