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Iridium complex with synergistic antitumor effect of chemotherapy and phototherapy and its preparation method and use

An anti-tumor effect, iridium complex technology, applied in the medical field to achieve the effects of reducing raw material loss, simple preparation method and molecular stability

Active Publication Date: 2020-08-14
GUANGXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Dozens of anti-tumor drugs currently used in clinical chemotherapy or adjuvant, only have a good curative effect on the treatment of some tumors

Method used

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  • Iridium complex with synergistic antitumor effect of chemotherapy and phototherapy and its preparation method and use
  • Iridium complex with synergistic antitumor effect of chemotherapy and phototherapy and its preparation method and use

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Embodiment Construction

[0024] The present invention will be further described in detail below in conjunction with the embodiments, so that those skilled in the art can implement it with reference to the description.

[0025]

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Abstract

The invention discloses an iridium complex with an anti-tumor effect through synergism of chemotherapy and phototherapy and a preparation method and application of the iridium complex. The iridium complex is characterized in that the chemical structural formula of the iridium complex is shown in the description. The iridium complex can be used for preparing medicines for treating cancers and hypertension, has the effects of chemotherapy and phototherapy, has good biological activity, has a conjugated system structure and is more stable in molecule. The preparation method is simple and low in cost.

Description

technical field [0001] The invention relates to the field of medical technology, in particular to an iridium complex having synergistic anti-tumor effects of chemotherapy and phototherapy, a preparation method and application thereof. Background technique [0002] Cancer is one of the most important diseases that endanger human health, and there is still no effective treatment. Most of the antineoplastic drugs currently used clinically are nucleoside drugs, which have similar antitumor spectrum and have strong toxic and side effects. On the other hand, some tumor cell lines are prone to drug resistance to clinically used drugs, and tumor cell lines are also prone to mutation. Therefore, the development of anti-tumor drugs that can overcome drug resistance or have broad-spectrum activity has attracted attention. The anti-tumor spectrum and anti-tumor mechanism of metal complexes are different from nucleoside drugs, which has aroused the interest of scientific researchers. D...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07F17/02A61K31/555A61K41/00A61P9/12A61P35/00
CPCA61K31/555A61K41/0057A61P9/12A61P35/00C07F17/02
Inventor 李培源苏炜霍丽妮陈睿
Owner GUANGXI UNIV OF CHINESE MEDICINE
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