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Traditional Chinese medicine composition for treating gouty arthritis and preparation method thereof

A technology of gouty arthritis and composition, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of gouty arthritis, which can solve the problems of unclear toxic and side effects, unclear principle of action, and complicated drug composition, so as to reduce kidney protection. effect, improvement of glomerular filtration rate, and significant renal protection

Inactive Publication Date: 2018-12-21
黄闰月
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] With the continuous deepening of clinical and basic research on the prevention and treatment of gout by traditional Chinese medicine, many prescriptions with the effect of treating gout, especially gouty arthritis, have emerged. Evaluate its therapeutic effect by clinical symptoms, not clear its mechanism of action, nor its toxic and side effects

Method used

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  • Traditional Chinese medicine composition for treating gouty arthritis and preparation method thereof
  • Traditional Chinese medicine composition for treating gouty arthritis and preparation method thereof
  • Traditional Chinese medicine composition for treating gouty arthritis and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0030] Prescription: 45 parts of Smilax, 30 parts of Astragalus, 8 parts of Campanulaceae, 20 parts of Alisma, 30 parts of Plantago and 30 parts of Epimedium.

[0031] Preparation method: Take all the raw materials according to the ratio, add water and soak for 30 minutes, the amount of soaking water should be 1-2 cm above the water surface of the medicinal materials, after soaking, boil with strong fire, then decoct with slow fire for 25 minutes, filter to get the liquid medicine, that is, the traditional Chinese medicine combination.

Embodiment 2

[0033] Prescription: 30 parts of Smilax, 20 parts of Astragalus, 5 parts of Campanulaceae, 10 parts of Alisma, 20 parts of Plantago and 15 parts of Epimedium.

[0034] Preparation method: Take all the raw materials according to the ratio, add water and soak for 45 minutes, the amount of soaking water should be 1-2 cm above the water surface of the medicinal materials, after soaking, boil with strong fire, then decoct with slow fire for 30 minutes, filter to obtain medicinal liquid, and concentrate the medicinal liquid It is made into a thick extract with a water content of 15-20%, and a pharmaceutically acceptable carrier is added to make a tablet.

Embodiment 3

[0036] Prescription: 55 parts of Smilax, 40 parts of Astragalus, 10 parts of Campanulaceae, 25 parts of Alisma, 30 parts of Plantago and 35 parts of Epimedium.

[0037]Preparation method: Take all the raw materials according to the ratio, soak in water for 30 minutes, the amount of soaking water should be 1-2cm above the water surface of the medicinal materials, after soaking, boil with strong fire, then decoct with slow fire for 25 minutes, filter to obtain medicinal liquid, and concentrate the medicinal liquid It is made into a thick extract with a water content of 15-20%, and a pharmaceutically acceptable carrier is added to make capsules.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating gouty arthritis. An active ingredient of the traditional Chinese medicine composition for treating the gouty arthritis is prepared from the following raw material medicines in parts by weight: 30-60 parts of rhizoma smilacis glabrae, 20-40 parts of radix astragali, 5-10 parts of radix platycodonis, 10-30 parts of rhizoma alismatis, 20-40 parts of semen plantaginis and 15-40 parts of herba epimedii. The traditional Chinese medicine composition for treating the gouty arthritis, disclosed by the invention, has the advantages of simple composition, good safety, no obvious toxic and side effects on lever and kidney, and obvious effect of reducing uric acid level and protecting the kidney. The traditional Chinese medicine composition for treating the gouty arthritis, disclosed by the invention, has the advantages that effect of the traditional Chinese medicine composition in reducing the uric acid level and improving inflammatory marks is equivalent to the effect of uric-acid-lowering drug benzbromarone; and the effect of the traditional Chinese medicine composition in improving glomerular filtration rate issuperior to the effect of the uric-acid-lowering drug benzbromarone.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating gouty arthritis and a preparation method thereof. Background technique [0002] Gout is a metabolic disease caused by abnormal purine metabolism leading to increased uric acid synthesis. Its disease sites are mainly in the joints, spleen, and kidneys, and are related to the liver and lungs. Gouty arthritis is the most common clinical manifestation. Traditional Chinese medicine believes that gout is mostly caused by overeating thick and greasy fat, and its pathogenesis is closely related to dampness, heat, phlegm, turbidity and blood stasis. In recent years, with the improvement of living standards and the adjustment of dietary structure, the intake of high-sugar, high-protein, high-fat, and high-purine diets has increased, leading to an increase in the incidence of gout year by year, seriously affecti...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/896A61P19/02A61P19/06A61P29/00
CPCA61K36/296A61K36/346A61K36/481A61K36/68A61K36/884A61K36/896A61K36/90A61K2236/331A61K2236/51A61P19/02A61P19/06A61P29/00A61K2300/00
Inventor 黄闰月赵越李君霞余华孙嗣龙
Owner 黄闰月
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