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vitamin b 12 Method for Partially Substituting Production Water for Pleuromutilin Fermentation with Production Wastewater

A technology for truncating pleuromutilin and producing wastewater, which is applied in the direction of microorganism-based methods, biochemical equipment and methods, fermentation, etc., can solve the problems of increasing the load and treatment costs of sewage treatment systems, high organic content, complex wastewater components, etc., Reach the effects of reducing the water used for the fermentation and production of pleuromutilin, simplifying the treatment process, and reducing the cost of environmental protection treatment

Active Publication Date: 2021-12-31
HEILONGJIANG LIANSHUN BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1) The content of organic matter is high, and the COD concentration is 60000-70000mg / L;
[0005] 2) The sugar content is high, and the total sugar content of the wastewater is 4-6%;
[0007] 4) The composition of wastewater is complex, mainly residual sugar, protein, organic acid, metabolic intermediate products and a small amount of vitamin B 12 Wait;
[0008] 5) The color of the wastewater is deep, dark brown, and there are many suspended solids
[0009] for vitamin B 12 Production wastewater (excluding cyanide-containing wastewater) currently has no effective and high value-added utilization methods, and it can only be discharged directly into the sewage treatment system, which not only increases the load and treatment costs of the sewage treatment system, but also causes a waste of resources

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Vitamin B 12 Production wastewater 50m 3 .

[0042] Pretreatment: First, vitamin B was adjusted with 10% sodium carbonate solution 12 The pH of the production wastewater was reduced to 9.1; secondly, the temperature was lowered to 5°C; finally, 400kg of sodium chloride was added and stirred for 20 minutes.

[0043] Adsorption treatment: vitamin B after the above pretreatment 12 Add 10 kg of perlite / coconut shell activated carbon composite adsorbent to the production wastewater, continue to stir for 40 minutes, and then let it stand for 60 minutes.

[0044] Ceramic membrane filtration: vitamin B after adsorption treatment 12 Wastewater is filtered through ceramic membranes to obtain primary treated water.

[0045] Ultrafiltration treatment: Control the temperature of the primary treatment water at 30°C, and perform circulating filtration in the cross-flow mode. The cross-flow flow rate is controlled at 9L / s, and the pressure is controlled at 0.1-0.2MPa. After the u...

Embodiment 2

[0052] Vitamin B 12 Production wastewater 50m 3 .

[0053] Pretreatment: First, vitamin B was adjusted with 12% sodium hydroxide solution 12 The pH of the production wastewater was reduced to 9.2; secondly, the temperature was lowered to 8°C; finally, 425 kg of sodium chloride was added and stirred for 25 minutes.

[0054] Adsorption treatment: vitamin B after the above pretreatment 12 Add 13kg of perlite / coconut shell activated carbon composite adsorbent to the production wastewater, continue to stir for 45 minutes, and then let it stand for 65 minutes.

[0055] Ceramic membrane filtration: vitamin B after adsorption treatment 12 Wastewater is filtered through ceramic membranes to obtain primary treated water.

[0056] Ultrafiltration treatment: Control the temperature of the primary treatment water at 35°C, and perform circulating filtration in the cross-flow mode. The cross-flow flow rate is controlled at 9.5L / s, and the pressure is controlled at 0.1-0.2MPa. After the...

Embodiment 3

[0063] Vitamin B 12 Production wastewater 50m 3 .

[0064] Pretreatment: First, vitamin B was adjusted with 15% sodium carbonate solution 12 The pH of the production wastewater was reduced to 9.3; secondly, the temperature was lowered to 10°C; finally, 450kg of sodium chloride was added and stirred for 30 minutes.

[0065] Adsorption treatment: vitamin B after the above pretreatment 12 Add 15 kg of perlite / coconut shell activated carbon composite adsorbent to the production wastewater, continue to stir for 50 minutes, and then let it stand for 70 minutes.

[0066] Ceramic membrane filtration: vitamin B after adsorption treatment 12 Wastewater is filtered through ceramic membranes to obtain primary treated water.

[0067] Ultrafiltration treatment: Control the temperature of the primary treatment water at 40°C, and perform circulating filtration in the cross-flow mode. The cross-flow flow rate is controlled at 10L / s, and the pressure is controlled at 0.1-0.2MPa. After the...

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Abstract

The invention relates to a vitamin B 12 The method of partially replacing the production water of pleuromutilin fermentation with production wastewater, the method is to use vitamin B after pretreatment, adsorption treatment, ceramic membrane filtration treatment and ultrafiltration treatment 12 Production waste water is directly reused as production water in the fermentation production of pleuromutilin. The present invention will be processed vitamin B 12 The production wastewater is directly reused in the fermentation production of pleuromutilin, which not only realizes the production of vitamin B 12 Wastewater zero discharge, reduce environmental pollution index and environmental protection treatment cost, for vitamin B 12 It provides a reliable basis for the clean industrial production of pleuromutilin, and at the same time, it can reduce the water used for fermentation and production of pleuromutilin, reduce its production cost, and provide a guarantee for the sustainable development of pleuromutilin.

Description

technical field [0001] The invention belongs to the technical field of biological fermentation wastewater treatment and reuse, and in particular relates to a vitamin B 12 The method of partially replacing the production water of pleuromutilin fermentation with production wastewater. Background technique [0002] Vitamin B 12 It is a cobalt-containing water-soluble vitamin, the main component of which is cyanocobalamin. It is clinically used to treat pernicious anemia and restore hematopoietic function, and is also used for nervous system diseases such as multiple neuritis and peripheral nerve paralysis. It is also used to treat liver diseases such as hepatitis and cirrhosis. For a long time, vitamin B 12 The clinical usage has grown steadily. In addition, vitamin B 12 It also forms a multivitamin product together with other vitamins, and is widely sold as an OTC drug and health food. [0003] Production of vitamin B by two-step fermentation 12 During the process, a l...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12P15/00C02F9/02C12R1/645
CPCC12P15/00C02F9/00C02F1/001C02F1/283C02F1/444
Inventor 任勇徐淑芬
Owner HEILONGJIANG LIANSHUN BIOTECHNOLOGY CO LTD
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