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Traditional Chinese medicine composition used for treating grouper pseudomonas plecoglossicida and preparation method and application thereof

A technology of Pseudomonas mutans and its composition, which is applied in the fields of pharmaceutical formulation, drug delivery, antibacterial drugs, etc., can solve the problem of no patents for the prevention and treatment of Pseudomonas mutans disease, no grouper Pseudomonas mutans To improve the survival rate, shorten the treatment time, and improve the efficacy of the drug

Inactive Publication Date: 2018-11-16
JIMEI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, the patents related to Pseudomonas mutans are all the use of the bacteria itself, there is no patent on the prevention and treatment of Pseudomonas mutans, and there is no report on the treatment plan for grouper Pseudomonas mutans

Method used

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  • Traditional Chinese medicine composition used for treating grouper pseudomonas plecoglossicida and preparation method and application thereof
  • Traditional Chinese medicine composition used for treating grouper pseudomonas plecoglossicida and preparation method and application thereof
  • Traditional Chinese medicine composition used for treating grouper pseudomonas plecoglossicida and preparation method and application thereof

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preparation example Construction

[0026] The invention provides the preparation method of described Chinese medicine composition, comprises the following steps:

[0027] 1) Pulverizing Coptis Rhizoma, Radix Astragali and Cortex Phellodendri to obtain Chinese medicine powder;

[0028] 2) Superfinely pulverizing the traditional Chinese medicine powder to obtain superfine medicine powder;

[0029] 3) Baking the ultrafine medicinal powder at 60-70° C. for 24-48 hours, and the obtained Chinese medicine fine powder is a Chinese medicine composition.

[0030] The present invention grinds coptis, astragalus and cortex cortex to obtain traditional Chinese medicine powder. The particle size of the pulverized traditional Chinese medicine powder is preferably 140-160 μm. More preferably, it is 150 μm. The pulverization includes pulverizing Coptis Rhizoma, Radix Astragali and Cortex Phellodendri separately or mixing Coptidis Rhizoma, Radix Astragali and Phellodendron Phellodendri according to the above ratio and then pu...

Embodiment 1

[0043] Purchase Coptis chinensis, Radix Astragali, Phellodendron Phellodendri from Lianfutang Pharmacy in Xiamen; pulverize traditional Chinese medicine with a traditional Chinese medicine pulverizer (FW177, Tianjin Test Instrument Co., Ltd.) , SQW-60, Shandong Sanqing Stainless Steel Equipment Co., Ltd.) for further pulverization until the particle size is 5-10 μm, and the superfine powder is collected for later use. The three kinds of ultrafine medicinal powders were baked at 60° C. for 48 hours to obtain fine powders of traditional Chinese medicines; the fine powders of traditional Chinese medicines obtained above were weighed, 0.9 kg of Coptidis Rhizoma fine powder, 1.3 kg of Astragalus membranaceus fine powder, and 0.9 kg of Phellodendron Phellodendri fine powder, The traditional Chinese medicine composition is obtained.

Embodiment 2

[0045] Pulverize the traditional Chinese medicines of Phellodendron Phellodendri, Coptidis Rhizoma, and Radix Astragali to 160 μm to obtain three kinds of traditional Chinese medicine powders; respectively ultrafinely pulverize the three kinds of traditional Chinese medicine powders to a particle size of 10 μm to obtain three kinds of ultrafine medicinal powders; Bake at 70°C for 24 hours to obtain fine powder of traditional Chinese medicine; weigh the fine powder of traditional Chinese medicine obtained above, 1.2 kg of fine powder of coptis, 0.9 kg of fine powder of astragalus, and 1.0 kg of fine powder of Cortex Phellodendri, and mix to obtain a traditional Chinese medicine composition.

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Abstract

The invention relates to a traditional Chinese medicine composition used for treating grouper pseudomonas plecoglossicida and a preparation method and an application thereof, which belong to the technical field of aquatic product culture. The traditional Chinese medicine composition comprises coptis, radix astragali and phellodendron amurense with mass ratio being 0.9-1.3:0.9-1.3:0.9-1.3. The traditional Chinese medicine composition can greatly increase the drug effect, and the survival rate by using the traditional Chinese medicine composition is increased by 60% and above by comparing with that of non-feeding of the traditional Chinese medicine composition. The traditional Chinese medicine composition has the advantages of scientific compatibility, low cost, short treatment course, fasteffectiveness, and high cure rate, and provides support for preventing and treating fish disease in culture production.

Description

technical field [0001] The invention belongs to the technical field of aquaculture, and in particular relates to a traditional Chinese medicine composition for treating grouper pseudomonas metamorphosis, a preparation method and application thereof. Background technique [0002] Pseudomonas plecoglossicida has been proved to be the pathogen of white spot disease in marine fish viscera in eastern Fujian. It is a common disease of seawater fish cultured in net cages, causing large-scale death of large yellow croakers and causing serious losses to the aquaculture industry. It is a typical temperature-dependent disease that breaks out at a water temperature of 16-20°C. When the water temperature exceeds 20°C The disease subsides spontaneously. Pseudomonas mutans can not only cause visceral white spot disease of cultured marine fish, but also can cause visceral white spot disease of grouper (Epinephelus) and other marine fish under artificial infection, and the mortality rate of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/14A61P31/04
CPCA61K36/718A61K9/0056A61K9/14A61K36/481A61K36/756A61K2236/15A61K2236/17A61P31/04A61K2300/00
Inventor 鄢庆枇徐晓津黄力行郑婉眉
Owner JIMEI UNIV
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