Detection kit for detecting lymphoma related gene group

A detection kit and lymphoma technology, applied in the field of molecular biology, can solve the limitations of lymphoma diagnostic methods and other problems, and achieve the effect of high detection rate and high detection efficiency

Inactive Publication Date: 2018-07-06
天津见康华美医学诊断技术有限公司
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Problems solved by technology

[0004] The purpose of the present invention is to aim at the technical defects of the prior art, and provide a detection kit for detecting lymphoma-related gene groups, so as to solve the limitation of the diagnosis method of lymphoma in the prior art and the lack of diagnosis of lymphoma from the perspective of molecular biology. based on

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  • Detection kit for detecting lymphoma related gene group
  • Detection kit for detecting lymphoma related gene group
  • Detection kit for detecting lymphoma related gene group

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Embodiment Construction

[0031] Specific embodiments of the present invention will be described in detail below. In order to avoid too many unnecessary details, well-known structures or functions will not be described in detail in the following embodiments. Unless defined otherwise, technical and scientific terms used in the following examples have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.

[0032] Materials and methods:

[0033] Among the patients diagnosed from September 2015 to April 2017 at the Hematology Hospital of Chinese Academy of Medical Sciences and Union Medical Diagnostic Center, according to the following criteria, we performed continuous enrollment (345 patients).

[0034] Inclusion criteria were: patients diagnosed with lymphoma by cytomorphology and flow cytometry.

[0035] The diagnostic results of 345 patients are shown in Table 3:

[0036] Table 3 List of patient diagnosis results

[0037]

[0038]

[0039...

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Abstract

The invention discloses a sequencing kit for screening lymphoma related gene mutation and a later medical interpretation database. A lymphoma related gene group comprises 22 genes such as MYD88 and TP53. The sequencing kit comprises multi-PCR (Polymerase Chain Reaction) primers for amplifying all exons of the 22 lymphoma related genes. The kit for screening lymphoma related gene mutation, which isdisclosed by the invention, has the characteristics of being high in detection efficiency, wide in mutation gene covering, high in detection rate, and the like, and a provided medical interpretationreport has the characteristics of being accurate and authoritative.

Description

technical field [0001] The invention relates to the technical field of molecular biology, and further relates to a detection kit for screening lymphoma-related gene mutations and a medical interpretation database thereof, in particular to a detection kit for detecting lymphoma-related gene groups. Background technique [0002] Lymphoma is a group of malignant tumors originating from lymph nodes or other lymphoid tissues. It can be divided into two categories: Hodgkin's disease (HD) and non-Hodgkin's lymphoma (NHL). Lymphocytes and (or ) tumorous hyperplasia of histiocytes, clinically painless lymphadenopathy is the most typical, hepatosplenomegaly is common, cachexia, fever and anemia are present in the advanced stage. The cell morphology of lymphoma is extremely complex. In the new classification of lymphoma in 2008, there are 80 subtypes. Due to the different location and scope of the lesion, the clinical manifestations are very inconsistent. The primary site can be in th...

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Application Information

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IPC IPC(8): C12Q1/6886C12Q1/6869C12N15/11
CPCC12Q1/6886C12Q1/6869C12Q2600/118C12Q2600/156C12Q2535/122
Inventor 汝昆蔺亚妮贾玉娇
Owner 天津见康华美医学诊断技术有限公司
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