Micro-fluidic chip, analysis device and control method of micro-fluidic chip

Abstract

The invention provides a micro-fluidic chip, an analysis device and a control method of the micro-fluidic chip. The micro-fluidic chip comprises multiple detection electrode assemblies arranged at intervals in the flowing direction of micro-droplets, wherein each detection electrode assembly comprises a first detection electrode and a second detection electrode which are spaced mutually and are used for forming a loop with the micro-droplets so as to determine the position of the micro-droplet. The micro-fluidic chip can realize real-time positioning of the micro-droplets, is low in cost and facilitates integration and miniaturization, interference of a biochemical reaction of the environment and the micro-droplets can be avoided through feedback by current, the operation data volume can be reduced only on the basis of existence of the micro-droplets, the reliability is increased, and driving of the micro-droplets cannot be affected due to low voltage.

Description

technical field [0001] The invention relates to the field of microfluidic technology, and in particular, to a microfluidic chip, an analysis device and a control method for the microfluidic chip. Background technique [0002] Electrowetting digital microfluidics uses the dielectric wetting effect to achieve separation, directional movement, and mixing of micro-droplets by controlling the voltage of the electrodes. In this method, the flatness of the hydrophobic layer in direct contact with the microdroplets is crucial, which directly affects the transport of the microdroplets. For example, dust, excessive surface roughness and other reasons will affect the flatness of the chip surface, resulting in the failure of the micro-droplets to be transported according to the predetermined timing, resulting in the failure of the reaction. In order to realize the automatic and accurate transportation of micro-droplets, it is necessary to detect the position of micro-droplets in real t...

AI Technical Summary

Problems solved by technology

At present, the visual feedback system is commonly used, but the equipment is expensive, the cost is high, and the amount of data to be processed is huge

[0003] Therefore, the related technologies of existing microfluidic chips still need to be improved.

Images