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System for calculating coronary fractional flow reserve based on arteriography images

An arteriography and coronary blood flow technology, applied in the field of auxiliary medicine, can solve problems such as functional and stenosis of areas of concern that cannot be quantified, and achieve the effects of increasing application promotion, smooth vessel outline, and accurate blood flow velocity at the entrance

Active Publication Date: 2018-06-22
HANGZHOU ARTERYFLOW TECH CO LTD
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Problems solved by technology

However, it is not possible to quantify the degree of functional stenosis in the region of interest (which is typically a narrow lesion)
[0006] Existing reconstruction and FFR calculation methods based on X-ray contrast: Adenosine needs to be injected and FFR calculated on the basis of contrast images; or FFR simulation is not performed on coronary arteries in a hyperemic state

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  • System for calculating coronary fractional flow reserve based on arteriography images
  • System for calculating coronary fractional flow reserve based on arteriography images
  • System for calculating coronary fractional flow reserve based on arteriography images

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Embodiment Construction

[0054] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, and do not limit the protection scope of the present invention.

[0055] The system provided in this embodiment is used to calculate FFR according to the collected electrocardiogram and the two-dimensional angiographic image matched with the electrocardiogram, so as to assist doctors in judging the heart state of the patient.

[0056] In this embodiment, for the first time, a single-view X-ray machine is used to take the first projected pole position (corresponding to the first emission source) V 1 Project X-rays to the patient, obtain the first angiographic image at the receiving end, and simultaneously acquire the first ECG; for the ...

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Abstract

The invention discloses a system for calculating coronary fractional flow reserve based on arteriography images. The system comprises at least one computer system and is characterized in that each computer system receives the arteriography images and electrocardiogram signals; corresponding two sequences of two-dimensional arteriography images under the identical electrocardiogram signal are selected; after the blood vessels of the arteriography images are determined, the topological structure diagram of coronary sections is generated, three-dimensional blood vessel central line sections are generated according to the topological structure diagram, and uniform rational b-spline curves are applied to the central line sections to build the three-dimensional geometrical model of the coronarysections; after inlet blood flow rate is determined according to the gray value change of two optional points at a model inlet in the dynamic arteriography images, computational fluid mechanics simulation analysis is performed according to the three-dimensional geometrical model having grids, the outlet / inlet blood flow rate, blood viscosity and blood density to obtain the pressure distribution ofthe coronary sections; aorta average pressure intensity in a congestive state is simulated, and the coronary fractional flow reserve distribution is determined according to the aorta average pressureintensity.

Description

technical field [0001] The invention belongs to the technical field of auxiliary medical treatment, and in particular relates to a system for calculating coronary blood flow reserve fraction based on arteriography images. Background technique [0002] Coronary atherosclerotic heart disease is a heart disease caused by atherosclerotic lesions in the coronary arteries that cause stenosis or blockage of the vessel lumen, resulting in myocardial ischemia, hypoxia or necrosis. It is often called "coronary heart disease". However, the scope of coronary heart disease may be broader, including inflammation, embolism, etc. leading to stenosis or occlusion of the lumen. [0003] Fractional Flow Reserve (FFR) refers to the maximum blood flow that can be obtained by the myocardial region supplied by the target measurement blood vessel in the case of coronary artery stenosis and the maximum blood flow that the same region can theoretically obtain under normal conditions. flow ratio. Ge...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B6/00A61B5/0402
CPCA61B6/481A61B6/504A61B6/507A61B6/5217A61B6/5247A61B5/318
Inventor 向建平夏永清冯立冷晓畅荆洪娟
Owner HANGZHOU ARTERYFLOW TECH CO LTD
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