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Use of the extract of Pseudomonas spp. as a medicine for preventing and treating pruritus

A technology of the extract of Pseudomonas ants, which is applied in the application and extraction field of the extracts of Pseudomonas ants, can solve the problems of not containing the extracts of Pseudomonas ants and no application, and achieve obvious antipruritic Activity, good industrialization prospect, simple and easy preparation method

Active Publication Date: 2020-08-07
GUANGXI DOUBLE ANT PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] From the retrieved literature, we can know that there is no medicine for treating pruritus and related diseases caused by the extract of Pseudomonas ant in the prior art, and the medicine for treating or inhibiting itching also does not contain P. Prickly ants extract; in the prior art, only Pseudomonas spp. extracts are disclosed as a drug for treating depression, rheumatoid or antifungal; however, there is no drug applied to related diseases related to pruritus, Therefore, how to expand the use of the extract of the black spiny ant, so that it can produce the greatest effect and exert its due effect, is still the main direction of medical and pharmaceutical research.

Method used

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  • Use of the extract of Pseudomonas spp. as a medicine for preventing and treating pruritus
  • Use of the extract of Pseudomonas spp. as a medicine for preventing and treating pruritus
  • Use of the extract of Pseudomonas spp. as a medicine for preventing and treating pruritus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1 Preparation of Pseudomonas spinosa extract

[0033] Take 1000g of Pseudomonas spp., add ethanol with a volume concentration of 95% and heat and reflux for extraction 3 times, 3L each time, each time the extraction pressure is -0.1MPa, the temperature is 45°C, combine the extracts, and recover under reduced pressure Ethanol, concentrated to 1.0 g / mL to obtain the extract.

Embodiment 2

[0034] Example 2 Preparation of the extract of Pseudomonas spinosa ants

[0035] Take 1000g of Pseudomonas spp., add ethanol with a volume concentration of 75% and heat and reflux for extraction 3 times, 3L each time, each time the extraction pressure is -0.09MPa, the temperature is 62°C, combine the extracts, and recover ethanol under reduced pressure , concentrated to 1.1 g / mL to obtain the extract.

Embodiment 3

[0036] Example 3 Preparation of Pseudomonas spinosa extract

[0037] Take 1000g of Pseudomonas spp., add petroleum ether (60-90) and heat and reflux to extract twice, 3L each time, each time the extraction pressure is -0.09MPa, the temperature is 80°C, combine the extracts, and recover under reduced pressure Petroleum ether was concentrated to 1.2 g / mL to obtain the extract.

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Abstract

The invention relates to the technical field of polyhachis vicina roger extract and in particular relates to application of the polyhachis vicina roger extract to preparation of a medicine for preventing and controlling pruritus and diseases caused by the pruritus. A preparation method of the polyhachis vicina roger extract, provided by the invention, comprises the following steps: reflowing and extracting by adopting ethanol or petroleum ether, decompressing and recycling an organic solvent and concentrating until the concentration being 1.0 to 1.2g / mL to obtain a product. The polyhachis vicina roger extract provided by the invention can be used for realizing various aims, is applied to foods and health-care foods and is also applied to medicines for treating diseases; the polyhachis vicina roger extract has scientific evidence to clinical application in the aspect of preventing or treating the pruritus.

Description

technical field [0001] The present invention relates to the technical field of an extract of the ants of the spiny ants, in particular to the use and extraction method of the extracts of the natural extracts of the spiny ants of the spiny ants. Background technique [0002] Pruritus (pruritus), a subjective sensation that evokes an immediate desire to scratch, is the most common common symptom of skin diseases. Modern research results confirm that itching is transmitted by peripheral nerve impulses to the posterior horn of the spinal cord gray matter, through the anterior association to the axon, and uploaded to the plate-like nucleus on the opposite side of the spinothalamus tract, and the third-order neurons of the thalamocortex transmit nerve impulses through the thalamic network Symptomatic activation system reaches the cerebral cortex to produce paresthesia. [0003] Pruritus can be divided into these diseases: (1) Neurological dysfunction skin diseases: neurodermatiti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K35/64A61P17/04A61P31/00A61P1/14A61P39/00A61P13/12A61P7/06A61P25/20A61P19/08A61P29/00A61P17/00A61P1/16A61P37/04A61P15/08
CPCA61K35/63
Inventor 韦桂宁李冬梅何飞苏启表曾宪彪陆国寿黄周锋胡筱希
Owner GUANGXI DOUBLE ANT PHARMA
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