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Acne removal traditional Chinese medicine composition as well as preparation method and application thereof

A technology of composition and traditional Chinese medicine, which is applied in the direction of drug combination, pharmaceutical formula, active ingredients of hydroxyl compounds, etc. It can solve the problems of easy damage to the skin balance system, skin allergies, etc., and achieve the effects of improving blood circulation, inhibiting growth, and reconciling qi and blood

Pending Publication Date: 2018-05-29
科丽思化妆品(上海)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the commonly used anti-acne ingredients on the market are mainly derived from chemical synthetic substances. These ingredients have the characteristics of strong efficacy and quick effect, but they are very irritating to the skin and easily destroy the original balance system of the skin. Skin allergies

Method used

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  • Acne removal traditional Chinese medicine composition as well as preparation method and application thereof
  • Acne removal traditional Chinese medicine composition as well as preparation method and application thereof
  • Acne removal traditional Chinese medicine composition as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1-4

[0036] Embodiment 1-4, comparative example 1-3 are the preparation technology of anti-acne Chinese medicine composition

Embodiment 1

[0038] Weigh the raw materials of Chinese herbal medicine, 20g of Scutellaria baicalensis, 15g of rhubarb, 8g of Sophora flavescens, 5g of Galla chinensis, 3g of licorice, 0.5g of dried ginger, add 30% ethanol according to the ratio of material to liquid at 1:15, reflux at 70°C for 2h, extract twice, and use 400 The purpose filter cloth is filtered, and the filtrates are combined; the filtrate is centrifuged for 10min at a speed of 5000r / min, the supernatant is collected, the supernatant is concentrated under reduced pressure until the concentration of the crude drug is 0.8g / ml, and 50% 1,3 butanediol is added for dissolution. It is used as a solvent and has the function of antisepsis. Centrifugal filtration collects the supernatant, and uses an organic microfiltration membrane system to filter and remove impurities and bacteria, collect the filtrate, add 0.1% ecological nutrient solution and 0.05% borneol, and stir Mix evenly to obtain the acne-removing traditional Chinese med...

Embodiment 2

[0040] Weigh the raw materials of Chinese herbal medicines, 50g of Scutellaria baicalensis, 40g of rhubarb, 30g of Sophora flavescens, 25g of Galla gall, 10g of licorice, add 95% ethanol according to the ratio of solid to liquid 1:10, reflux at 80°C for 1h, extract 3 times, filter with 2000 mesh filter cloth, Combine the filtrates; centrifuge the filtrates for 15min at a speed of 6000r / min, collect the supernatant, concentrate the supernatant under reduced pressure to a crude drug concentration of 1.02g / ml, add 30% 1,3 butanediol to dissolve, use as a solvent, and Play the role of anti-corrosion, centrifugal filtration, collect the supernatant, and use organic microfiltration membrane system to filter bacteria and remove impurities, collect the filtrate, add 0.5% ecological nutrient solution and 0.1% borneol, stir and mix evenly to obtain Acne-removing traditional Chinese medicine composition.

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Abstract

The invention provides an acne removal traditional Chinese medicine composition. The acne removal traditional Chinese medicine composition is prepared by mixing extract liquid of the following components in parts by weight and ecologic nutritional solution, 20 to 50 parts of radix scutellariae, 15 to 40 parts of radix et rhizoma rhei, 8 to 30 parts of radix sophorae flavescentis, 5 to 25 parts ofgalla chinensis, 3 to 10 parts of licorice roots and 0 to 5 parts of dry gingers. The invention also provides a preparation method of the acne removal traditional Chinese medicine composition. The preparation method comprises the following steps: heating, refluxing and extracting by using ethanol, filtering, centrifuging filtrate, dissolving, performing membrane separation treatment, adding ecological nutritional solution and the like; on one hand, the radix scutellariae alcohol extract is obtained by virtue of the ethanol refluxing extraction, and the antibacterial and anti-inflammation effect is good; and on the other hand, by adding the ecological nutritional solution, acne propionibacteria causing the acnes can be prevented, the regeneration state of saprophytic bacteria is optimized,the micro ecology of the skin is regulated, and the balance of the biologic flora is maintained. The invention also provides application of the traditional Chinese medicine composition in cosmetics. The acne removal traditional Chinese medicine composition is non-irritating to the skin.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a traditional Chinese medicine composition for removing acne and its preparation method and application. Background technique [0002] Acne, usually called acne in daily life, is an infectious skin disease of the pilosebaceous glands. Abnormal sebum metabolism produces excessive fatty acids and excessive proliferation of Propionibacterium acnes in a closed environment, which causes the skin to produce an inflammatory response. The clinical manifestations are It is prone to pleomorphic skin lesions such as acne, papules, pustules, and nodules on the face. In modern life, due to the influence of the rhythm of life and eating habits, acne and the acne marks formed after acne healing are bothering many beauty lovers. Usually, in addition to drug therapy and improving diet, many people also choose to use cosmetics to treat acne. According to the 2016 Cosmetics Industry...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P17/10A61P31/02A61P31/04A61K8/98A61K8/9794A61K8/9789A61K8/34A61K8/73A61K8/60A61Q19/00A61Q17/00A61K35/64A61K31/045A61K31/733A61K31/702
CPCA61K36/9068A61Q17/005A61Q19/00A61K8/34A61K8/60A61K8/73A61K8/97A61K8/987A61K31/045A61K31/702A61K31/733A61K35/63A61K36/484A61K36/489A61K36/539A61K36/708A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2800/5922A61K2300/00
Inventor 雷登凤高合意曾飒周海军
Owner 科丽思化妆品(上海)有限公司
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