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A feed additive for alleviating endoplasmic reticulum stress of sea bass, its preparation method and application

A feed additive, sea bass technology, applied in the field of feed additives for relieving endoplasmic reticulum stress of sea bass and its preparation field, can solve the problem that liver fat cannot be effectively transported, the anti-stress ability of sea bass is reduced, liver fat is excessively accumulated, etc. problems, to improve antioxidant capacity, reduce oxidative damage, and improve Ca2+ homeostasis

Active Publication Date: 2019-07-26
JIMEI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Endoplasmic reticulum stress can lead to ineffective transport of hepatic fat to extrahepatic tissues, resulting in excessive accumulation of hepatic fat
In addition, endoplasmic reticulum stress can also lead to oxidative damage and apoptosis of cells, resulting in a decrease in the stress resistance of sea bass

Method used

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  • A feed additive for alleviating endoplasmic reticulum stress of sea bass, its preparation method and application
  • A feed additive for alleviating endoplasmic reticulum stress of sea bass, its preparation method and application
  • A feed additive for alleviating endoplasmic reticulum stress of sea bass, its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Before mixing, all raw materials are ultrafinely pulverized and passed through an 80-mesh sieve, containing 20 parts by weight of alfalfa saponin, 10 parts by weight of methionine chelated zinc, 5 parts by weight of taurine, 20 parts by weight of feed additives per 100 parts by weight of the feed additive. Pueraria root powder in parts by weight, grape seed proanthocyanidins in 5 parts by weight, and the balance in the proportion of defatted rice bran are mixed to obtain a feed additive for alleviating endoplasmic reticulum stress of sea bass.

[0054] Among them, the ligand ratio of methionine chelated zinc is 3.5:1, and the chelation rate of zinc in methionine chelated zinc is 89%.

Embodiment 2

[0056] The difference between this embodiment and Example 1 is: before mixing, all the raw materials are ultrafinely pulverized and passed through a 100-mesh sieve, and the feed additive contains 30 parts by weight of alfalfa saponin and 20 parts by weight of methionine chelate Zinc, 15 parts by weight of taurine, 30 parts by weight of kudzu root powder and 10 parts by weight of grape seed proanthocyanidins, and the balance is the ratio of defatted rice bran to mix the raw materials to obtain a feed additive for alleviating the stress of sea bass endoplasmic reticulum .

Embodiment 3

[0058] The difference between this embodiment and Example 1 is: before mixing, all the raw materials are ultrafinely pulverized and passed through a 90-mesh sieve, and the feed additive contains 23 parts by weight of alfalfa saponin and 12 parts by weight of methionine chelate Zinc, 8 parts by weight of taurine, 22 parts by weight of kudzu root powder and 6 parts by weight of grape seed proanthocyanidins, and the balance is the proportion of defatted rice bran. The raw materials are mixed to obtain a feed additive for alleviating the stress of sea bass endoplasmic reticulum .

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Abstract

The invention relates to a feed additive capable of relieving endoplasmic reticulum stress of jewfishes as well as a preparation method and application of the feed additive, and belongs to the field of feeds. Each 100 parts by weight of the feed additive comprises 20-30 parts by weight of alfalfa sapinogenin, 10-20 parts by weight of chelated zinc methionine, 5-15 parts by weight of taurine, 20-30parts by weight of radix puerariae powder, 5-10 parts by weight of grape seed proanthocyanidins, and the balance of a carrier. The raw materials of the feed additive are safe and free from harmful remaining, and create conditions for production of a green feed and aquatic products. The preparation method of the feed additive comprises the following steps of mixing the raw materials in parts by weight. The preparation method is simple, good in condition controllability and good in stability, and has favorable application prospects. The feed additive is applied to preparation of a jewfish feed,the antioxidant ability of livers of the jewfishes can be improved, the oxidative damage of endoplasmic reticulum can be reduced, the endoplasmic reticulum stress protein expression can be reduced, the endoplasmic reticulum stress can be relieved, and the endoplasmic reticulum can be maintained stable.

Description

technical field [0001] The invention relates to the field of feed, and in particular to a feed additive for alleviating endoplasmic reticulum stress of sea bass, a preparation method and application thereof. Background technique [0002] In recent years, the frequent occurrence of fatty liver in cultured sea bass is a common problem faced by the aquaculture industry, especially in high temperature seasons, sea bass is prone to fatty liver. Fatty liver will not only reduce the growth rate and feed conversion rate of sea bass, but also reduce the anti-stress ability of sea bass. Once sea bass suffers from stress such as high temperature and high ammonia nitrogen, it is easy to die in large numbers, which will bring huge economic benefits to sea bass farming. loss. [0003] At present, many studies have shown that endoplasmic reticulum stress plays a very important role in the occurrence and harm of fatty liver, and endoplasmic reticulum stress is accompanied by the occurrence...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23K10/30A23K20/121A23K20/142A23K20/163A23K20/20A23K50/80
CPCA23K10/30A23K20/121A23K20/142A23K20/163A23K20/20A23K20/30A23K50/80Y02A40/818Y02P60/87
Inventor 鲁康乐张春晓王玲宋凯
Owner JIMEI UNIV
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