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An oral drug for the treatment of respiratory tract infections

A respiratory and drug technology, applied in the field of plant materials, can solve problems such as high price

Active Publication Date: 2021-06-25
重庆希尔安药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are some Chinese patent medicines for respiratory tract infection in the market, such as Zhiji syrup, loquat cough syrup, etc., but these medicines are mainly designed for a certain stage of respiratory tract infection such as acute bronchitis or bronchitis, or for respiratory tract infection. It is designed for certain symptoms such as cough, expectoration, etc., and it treats a certain symptom or a certain pathological link, and the price is expensive

Method used

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  • An oral drug for the treatment of respiratory tract infections
  • An oral drug for the treatment of respiratory tract infections
  • An oral drug for the treatment of respiratory tract infections

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Taking the production of 1000 mL of pharmaceutical oral liquid product of the present invention as an example, the used Chinese medicine raw materials and auxiliary materials and their proportioning ratio are:

[0037] Forsythia 130 g

[0038] Mountain silver flower 110 g

[0039] Nepeta 90 g

[0040] Mulberry leaves 90 g

[0041] Bupleurum 110 g

[0042] Scutellaria baicalensis 90 g

[0043] Folium 130 g

[0044] Vitex 90 g

[0045] Burdock 90 g

[0046] Licorice 30 g

[0047] Add distilled water to 1000 mL.

[0048] Its preparation method is as follows:

[0049] With the Chinese medicine of the present invention, add 12 times the amount of water for the first time to soak for 2 hours, decoct for 1.0 hour, add 10 times the amount of water for the second time and decoct for 1.0 hour, filter, combine the filtrates, and concentrate to a relative density of 1.10~ 1.20 (measured at 60°C), add ethanol to make the alcohol content reach 70%, let it stand for 24 hours...

Embodiment 2

[0096] Taking the production of 1000 mL of pharmaceutical oral liquid product of the present invention as an example, the used Chinese medicine raw materials and auxiliary materials and their proportioning ratio are:

[0097] Forsythia 171.4 g

[0098] Mountain silver flower 85.7 g

[0099] Nepeta 85.7 g

[0100] Mulberry leaves 85.7 g

[0101] Bupleurum 85.7 g

[0102] Scutellaria baicalensis 85.7 g

[0103] Folium 171.4 g

[0104] Vitex 85.7 g

[0105] Burdock 85.7 g

[0106] Licorice 17.1 g

[0107] Add distilled water to 1000 mL.

[0108] Its preparation process is the same as that of the oral liquid in Example 1. Each bottle contains 10 mL, and each mL contains 0.96 g of traditional Chinese medicine raw materials.

[0109] Taking the production of 1000 g of the granule product of the present invention as an example, the used Chinese medicine raw materials and auxiliary materials and their mass proportions are:

[0110] Forsythia 171.4 g

[0111] Mountain silve...

Embodiment 3

[0155] Taking the production of 1000 mL of pharmaceutical oral liquid product of the present invention as an example, the used Chinese medicine raw materials and auxiliary materials and their proportioning ratio are:

[0156] Forsythia 134 g

[0157] Mountain silver flower 112 g

[0158] Nepeta 89 g

[0159] Mulberry leaves 89 g

[0160] Bupleurum 112 g

[0161] Scutellaria baicalensis 89 g

[0162] Folium 112 g

[0163] Vitex 89 g

[0164] Burdock 89 g

[0165] Licorice 45 g

[0166] Add distilled water to 1000 mL.

[0167] Its preparation process is the same as that of the oral liquid in Example 1. Each bottle contains 10 mL, and each mL contains 0.96 g of traditional Chinese medicine raw materials.

[0168] Taking the production of 1000 g of the granule product of the present invention as an example, the used Chinese medicine raw materials and auxiliary materials and their mass proportions are:

[0169] Forsythia 134 g

[0170] Mountain silver flower 112 g

[0...

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Abstract

An oral medicine for treating respiratory tract infection, which is composed of 10-30 parts of forsythia, 5-25 parts of mountain silver flower, 5-20 parts of nepeta, 5-20 parts of mulberry leaves, 5-25 parts of bupleurum and 5 parts of scutellaria baicalensis The medicament prepared by the conventional preparation method from Chinese medicine raw materials in proportions of 20-20 parts, 10-25 parts of Daqingye, 5-20 parts of vitex, 5-20 parts of arctium, and 1-10 parts of licorice. The drug efficacy test shows that the drug of the present invention can inhibit and kill common pathogenic bacteria and viruses of respiratory tract infection in vitro, block the infection of cells by viruses, and inhibit the proliferation of viruses in cells; it can inhibit the growth of bacteria and viruses in mice. Infection in the body can reduce lung inflammation caused by bacterial and viral infections; it has a significant antipyretic effect on the rabbit fever model caused by typhoid and paratyphoid fever; it has a significant anti-inflammatory effect on the mouse abdominal capillary permeability model. Toluene-induced mouse auricle swelling model has significant anti-inflammatory effect; and has significant analgesic effect.

Description

technical field [0001] The invention belongs to the technical field of medical preparations containing raw materials or their reaction products with unknown structures, and specifically relates to materials derived from plants. Background technique [0002] Respiratory tract infection is the most common clinical respiratory disease, and the onset is more common in autumn and winter, winter and spring, and summer and autumn when the seasons change. It is especially harmful to children, the elderly, and people with weak constitutions. failure, or even death. Clinical manifestations include cough, expectoration, headache, sore throat, hoarseness, fever, chills, and general malaise. [0003] Drugs currently on the market for the treatment of respiratory infections are mainly antibiotics, or selective concomitant hormones. With the emergence of bacterial drug resistance and the side effects of a large number of clinical use of antibacterial drugs, the development of natural Chi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/85A61K36/855A61P11/00A61P29/00A61P31/00
CPCA61K36/195A61K36/233A61K36/28A61K36/315A61K36/355A61K36/484A61K36/538A61K36/539A61K36/605A61K36/634A61K36/704A61K36/85A61K36/855A61K2300/00Y02A50/30
Inventor 马耀茹杨成赵卉
Owner 重庆希尔安药业有限公司
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