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Application of pithecellobium cypearia or extract to preparation of medicine for treating and/or adjunctively treating bronchopneumonia of livestock and poultry

A technology for bronchopneumonia and adjuvant therapy, applied in drug combinations, plant/algae/fungus/moss ingredients, pharmaceutical formulations, etc., can solve problems such as food safety issues, drug residues, inability to completely eliminate infection risks, and achieve clear efficacy. , better treatment effect

Inactive Publication Date: 2018-05-01
CHENGDU QIANKUN VETERINARY PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The common treatment method is to regularly feed the infected pigs and high-risk pigs with macrocyclic lipid antibiotics, but the effect will be unsatisfactory due to the problem of drug resistance, and the residue of the drug will cause food safety problems
Another method is to immunize high-risk pigs with vaccines. However, most of the mycoplasma vaccines are imported at present, and the cost is high. In addition, there are many subtypes of mycoplasma pathogens, and often immunotherapy cannot completely eliminate the risk of infection
However, there is no literature report on the use of monkey earrings for livestock and poultry bronchopneumonia, and there is no literature report on the combined use of monkey earrings and tiamulin

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation of embodiment 1 monkey earring extract of the present invention

[0025] Take 100g of monkey earring medicinal material, add 2L of distilled water to soak for 10h, decoct until boiling, then decoct with slow fire for 1.5h, add 15 times distilled water to the residue after filtration and continue to decoct for 1.5h, then filter and mix the filtrate twice, and concentrate in a rotary evaporator at 60°C It is used as 1g / ml raw medicine clear ointment for later use. Then add 95% ethanol until the ethanol content is 75%, filter and remove the residue after standing overnight, reclaim ethanol, then continue to add 95% ethanol until the alcohol content is 85%, filter and remove the residue after standing overnight, concentrate and reclaim ethanol, Get 2.5g / ml crude drug clear ointment.

Embodiment 2

[0026] Embodiment 2 The preparation of monkey earring oral liquid of the present invention

[0027] Take the monkey earring medicinal material, add 20 times distilled water to soak for 10 hours, boil until boiling, then simmer for 1.5 hours, add 15 times distilled water to the residue after filtering and continue to cook for 1.5 hours, then filter and mix the filtrate twice, and concentrate in a rotary evaporator at 50°C It is used as 1g / ml raw medicine clear ointment for later use.

[0028] Then add 95% ethanol until the ethanol content is 75%, filter and remove the residue after standing overnight, reclaim ethanol, then continue to add 95% ethanol until the alcohol content is 85%, filter and remove the residue after standing overnight, concentrate and reclaim ethanol, Get 2.5g / ml crude drug clear ointment, set aside.

[0029] Add 0.8g of Tween-80 and 0.02g of potassium sorbate to 100ml of clear cream, mix evenly and divide into packages.

Embodiment 3

[0030] Embodiment 3 preparation of medicine of the present invention

[0031] Take 100ml of the monkey earring extract prepared in Example 1 and 100g of tiamulin, and mix them.

[0032] Prove the beneficial effect of the present invention by concrete clinical test below.

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PUM

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Abstract

The invention provides application of pithecellobium cypearia or extract to preparation of a medicine for treating and / or adjunctively treating bronchopneumonia of livestock and poultry. The inventionalso provides a medicinal composition for treating bronchopneumonia of livestock and poultry. The invention also provides a preparation method and application of the medicinal composition. The pithecellobium cypearia can be used for treating and / or adjunctively treating bronchopneumonia of livestock and poultry, has a clear medicinal effect, has a more excellent treatment effect on bronchopneumonia when being used together with tiamulin, and has a good clinical application prospect.

Description

technical field [0001] The invention relates to the use of monkey earrings or extracts in the preparation of medicines for treating and / or assisting the treatment of livestock and poultry bronchopneumonia, belonging to the field of veterinary medicine. Background technique [0002] Mycoplasma pneumonia in livestock and poultry is one of the most common background diseases in veterinary clinics. After livestock and poultry are infected with mycoplasma pneumonia, it will not only manifest as panting, coughing, and decreased production performance; as a background disease, it will also cause the immune function of the body to decline. It is more likely to cause respiratory system lesions and other pathogenic infections. [0003] The common treatment method is to regularly feed macrocyclic lipid antibiotics to infected pigs and high-risk pigs, but the effect is not ideal due to drug resistance, and drug residues will cause food safety problems. Another method is to immunize hig...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P11/00A61K31/22
CPCA61K36/48A61K31/22A61K2236/331A61K2236/53A61K2300/00
Inventor 李超唐华侨杨海涵胡婷婷杨婷秀
Owner CHENGDU QIANKUN VETERINARY PHARMA
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