Application of Bacillus coagulans in preparation of blood uric acid lowering preparation

A technology of Bacillus coagulans and blood uric acid, applied in the fields of application, urinary system diseases, function of food ingredients, etc.

Active Publication Date: 2018-03-30
QINGDAO EASTSEA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The inventors have found through research that Bacillus coagulans can effectively reduce blood uric acid levels, prevent or treat hyperuricemia, gout and gout complications, and is safe without any toxic and side effects. The effect is better than Lactobacillus, and no relevant research reports have been seen. Special application for this invention patent

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation Embodiment 1

[0033] Preparation Example 1 The preparation of bacillus coagulans powder

[0034] 1 Preparation of bacteria powder and identification of strains

[0035] Take samples of human feces, soil, haystack substrate, etc., and then put the samples in a sterilized bottle, take 2 grams of the sample and add it to 18mL of sterilized diluent, mix well, and carry out 10 -1 、10 -2 、10 -3 、10 -4 , 10-5 , 10 -6 , 10 -7 Gradient dilution, take 10 -5 , 10 -6 , 10 -7 Three dilution gradients, spread on the solid medium for selective single colony isolation of Bacillus coagulans, place in an incubator, culture at 37°C for 48 hours, select a single colony with good growth and inoculate it into the liquid expansion medium of Bacillus coagulans , expanded at 37°C for 48 hours. After the obtained culture solution is centrifuged (12000rpm) to separate the thalline, the thalline is freeze-dried in vacuum to prepare dry bacterial powder, and the number of viable bacteria is 1×10 9 CFU / g or m...

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PUM

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Abstract

The invention discloses an application of Bacillus coagulans in the preparation of a blood uric acid lowering preparation. The application is concretely characterized in that the Bacillus coagulans isused to lower the blood uric acid and prevent or treat hyperuricemia, gout and gout complications.

Description

technical field [0001] The invention relates to the application of bacillus coagulans in the preparation of preparations for reducing blood uric acid, in particular to the use of bacillus coagulans to reduce blood uric acid and prevent or treat hyperuricemia, gout and gout complications. Background technique [0002] Hyperuricemia is the biochemical basis of the pathogenesis of gout, with blood uric acid consistently higher than the normal range as the core symptom. According to a 2008 research survey, 1% to 2% of adults in the world suffer from gout, and the number is increasing at a rate of 4 million per year. It is particularly serious in my country, where the incidence rate of gout is 6.89%, and it even reaches 15.09% in the southeast coast. Gout brings great suffering to patients, directly affects the quality of life, and may be life-threatening. Due to the limited means of prevention and treatment at present, the treatment is slow, causing huge mental pressure and ec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/742A61K35/747A61P19/06A61P13/12A23L33/135A23L2/38
CPCA23L2/38A23L33/135A61K35/742A61K35/747A23V2002/00A61K2300/00A23V2200/30
Inventor 崔云龙赵婀姿李洪福
Owner QINGDAO EASTSEA PHARMA
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