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A centrifugal separation detection device and its application

A detection device and centrifugal separation technology are applied in the field of instrument analysis to achieve the effects of reducing background noise interference, shortening detection time, and simple operation steps

Active Publication Date: 2020-05-15
CHANGZHOU BIOWIN BIOPHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

High sensitivity, rapidity, miniaturization, full quantification, and automation are the current development trends of clinical immunoassay technology products, but none of the existing ones can achieve the above functions at the same time

Method used

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  • A centrifugal separation detection device and its application
  • A centrifugal separation detection device and its application
  • A centrifugal separation detection device and its application

Examples

Experimental program
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Effect test

Embodiment 1

[0041] Embodiment 1, the preparation of horizontal centrifugal separation detection device

[0042] like figure 1As shown, the centrifugal separation detection device of the present invention includes: a sample feeding part 1 , a solid phase membrane 2 , a centrifugal device (a centrifugal rotor 3 ; a drive motor 5 ; a support base 6 ) and a detector 4 . It also includes ultrasonic breaking device 7 and casing 8 . The proximal end of the solid-phase membrane 2 corresponding to the sampling part 1, the ultrasonic breaking device 7 corresponds to the detection part of the solid-phase membrane 2, and the centrifugal device is composed of a centrifugal rotor 3, a drive motor 5 and a support base 6, and the drive motor 5 is located on the support base. On the base 6 , the centrifugal rotor 3 is driven to rotate by the driving motor 5 .

[0043] like figure 1 and figure 2 As shown, the solid-phase membrane 2 is provided with a liquid adsorption and dispersion part 9 connected t...

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Abstract

The invention discloses a centrifugal separation detection device. The centrifugal separation detection device comprises a sample feeding part, a solid phase membrane, a centrifugal device and a detector, wherein the centrifugal device comprises a centrifugal rotor and a support base; the centrifugal rotor is driven by a drive motor, and is supported by the support base; the sample feeding part isnot directly connected with the centrifugal rotor, and is arranged above, under or outside the centrifugal rotor; the sample feeding part comprises a liquid phase storage device, a sample feeding pipe and a sample feeding pump; the liquid phase storage device is communicated with the sample feeding pipe; the sample feeding pump is used for driving liquid in the liquid phase storage device to enter the sample feeding pipe; the solid phase membrane is arranged on the centrifugal rotor, and a liquid phase sample is directly or indirectly loaded onto one side, near the center, of the solid phasemembrane by the sample feeding pipe; the detector is not directly connected with the centrifugal rotor, and is arranged above, under or outside the centrifugal rotor. The centrifugal separation detection device is characterized in that the sensitivity is high, and the full-quantitative and automatic effects are realized; the detection technology with quick detection and simple used equipment is adopted, and the good application prospect is realized.

Description

technical field [0001] The invention relates to a centrifugal separation detection device and its application, belonging to the field of instrument analysis. Background technique [0002] Immunological detection technology is an experimental method designed by applying the principles of immunology to determine antigens, antibodies, immune cells and chemical components. Samples for analytical, food and industrial analysis. Commonly used immunoturbidity technology, solid-phase enzyme immunoassay technology, chemiluminescent detection technology, immunofluorescence labeling technology, flow cytometry, colloidal gold technology, etc. Immunoturbidimetry, also known as immunoturbidimetry, is the specific combination of soluble antigens and antibodies in the liquid phase to produce complexes of a certain size, which form light refraction or absorption, and measure the transmitted or scattered light after refraction or absorption. As a calculation unit, it is used for quantitative...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/558
CPCG01N33/558
Inventor 刘凤鸣
Owner CHANGZHOU BIOWIN BIOPHARM
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