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Oral pharmaceutical preparation for treating neurogenic headache and preparation method of oral pharmaceutical preparation for treating neurogenic headache

A technology of pharmaceutical preparations and oral preparations, applied in the field of medicine, can solve the problems of inability to fundamentally treat nervous headaches, large side effects of pure chemical drugs, exacerbation of nervous headaches, etc., achieve relief and treatment of headaches, dizziness, significant curative effect, and improve mood Effect

Inactive Publication Date: 2018-02-13
黄建文
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Pure chemical drugs for neuropathic headaches have large side effects and cannot fundamentally treat neuropathic headaches. Patients can easily aggravate neuropathic headaches when they are stressed, tired, excited, angry, anxious or depressed.
However, Chinese patent medicines have defects such as slow effect and insufficient curative effect to varying degrees, which need to be improved.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A preparation method of an oral pharmaceutical preparation for treating neuropathic headache comprises the following steps:

[0018] S1: Weigh 10 parts of Melaleuca, 10 parts of Comfrey, 15 parts of Magnolia Magnolia, 15 parts of Uncaria, 15 parts of Wang Buliuxing, and 15 parts of Zianzao Ren, decoct twice with water, combine the decoction liquid, and concentrate the filtrate into clear ointment;

[0019] S2: Weigh 2 parts of aspirin and 2 parts of mianserin, grind them into fine powder, mix evenly with the clear paste in step S1, add pharmaceutically acceptable excipients, granulate, dry, and size the granules to make granules.

Embodiment 2

[0021] A preparation method of oral granules for the treatment of neuropathic headache comprises the following steps:

[0022] S1: Weigh 15 parts of Melaleuca, 15 parts of Comfrey, 17 parts of Magnolia Magnolia, 17 parts of Uncaria, 17 parts of Wangbuliuxing, and 17 parts of Zianzaoren, decoct twice with water, combine the decoction liquid, and concentrate the filtrate into clear ointment;

[0023] S2: Weigh 4 parts of aspirin and 3 parts of mianserin, grind them into fine powder, mix evenly with the clear paste in step S1, add pharmaceutically acceptable excipients, granulate, dry, and size the granules to make granules.

Embodiment 3

[0025] A preparation method of oral granules for the treatment of neuropathic headache comprises the following steps:

[0026] S1: Weigh 20 parts of Melaleuca, 20 parts of Comfrey, 20 parts of Magnolia Magnolia, 20 parts of Uncaria Uncaria, 20 parts of Wang Buliuxing, 20 parts of Zianzao Seed, decoct twice with water, combine the decoction liquid, and concentrate the filtrate into clear ointment;

[0027] S2: Weigh 5 parts of aspirin and 5 parts of mianserin, grind them into fine powder, mix evenly with the clear paste in step S1, add pharmaceutically acceptable excipients, granulate, dry, and sizing to make granules.

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PUM

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Abstract

The invention relates to an oral pharmaceutical preparation for treating neurogenic headache and a preparation method of the oral pharmaceutical preparation for treating neurogenic headache. Effectivecomponents of the oral pharmaceutical preparation are made by compounding of Chinese herbal medicines and western medicines, wherein Chinese herbal medicine components are prepared from, by weight, 10-20 parts of Cortex Melaleucae Leucadendrae, 10-20 parts of Radix Arnebiae seu lithospermi, 15-20 parts of Flos Magnoliae, 15-20 parts of Ramulus Uncariae Cum Uncis, 15-20 parts of Semen Vaccariae and 15-20 parts of Semen Ziziphi Spinosae; the western medicines include, by weight, 1-5 parts of aspirin and 1-5 parts of mianserin. Since the pharmaceutical composition is formed by compounding of theChinese herbal medicines and the western medicines, defects of slow action and unremarkable curative effects of the Chinese herbal medicine components and high side effects, proneness to dependence,failure in fundamental treatment of migraine, and the like of the western medicines are overcome. By mutual supplementation of Chinese herbal medicine and western medicine components, the oral pharmaceutical preparation has a remarkable curative effect in treatment of neurogenic headache, is effective in improvement of emotion and sleep of patients and alleviation of symptoms such as headache anddizziness and is low in toxic and side effect, high in cure rate and quick in action.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an oral pharmaceutical preparation for treating nervous headache and a preparation method thereof. Background technique [0002] Nervous headaches are caused by irregular life, excessive smoking and alcohol, and sleeping. Nervous headaches mainly refer to tension headaches, functional headaches, and vascular neuropathic headaches. They are mostly caused by mental stress and anger. The main symptom is persistent head fullness. Pain, pressure, and heaviness, and some patients complained that there was a "tightening" feeling in the head. Majority of patients is bilateral headache, mostly two temporo sides, rear occiput and parietal or whole head. The nature of headache is dull pain, distending pain, pressure, numbness and band-like tightness. The intensity of the headache is mild to moderate, and it is rarely bedridden or affects daily life due to the headache. The p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61P25/00A61P25/20A61P1/08A61K31/616A61K31/55
CPCA61K36/61A61K9/0053A61K31/55A61K31/616A61K36/30A61K36/36A61K36/575A61K36/725A61K36/74A61K2236/331A61K2236/39A61K2300/00
Inventor 黄建文
Owner 黄建文
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