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Scar-free regenerated medicinal dressing with tissue induction function and preparation method of scar-free regenerated medicinal dressing

A scar-free, functional technology, used in medical science, bandages, absorbent pads, etc., can solve problems such as environmental pollution, PU cannot be naturally degraded, etc.

Inactive Publication Date: 2018-01-30
COMSCAFFOLDS NANJING MEDICAL DEVICE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, PU cannot be degraded naturally, so it will pollute the environment. Therefore, research on degradable PU materials has gradually become one of the hotspots in this field.

Method used

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  • Scar-free regenerated medicinal dressing with tissue induction function and preparation method of scar-free regenerated medicinal dressing
  • Scar-free regenerated medicinal dressing with tissue induction function and preparation method of scar-free regenerated medicinal dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] A non-scar regenerative medical dressing with tissue induction function for wounds with little exudate, the preparation method of which is as follows:

[0053] (1) Dissolve degradable polyurethane in chloroform solution to make a 15% solution, and use electrospinning technology to spin a film with a pore size of 10-150 μm and a thickness of 0.1-0.2 mm, and evenly coat a layer of silicon Gels, which are absorbable medical patches;

[0054] (2) Evenly coat the sodium hyaluronate gel on the absorbable medical film obtained in step (1), and dry or air dry;

[0055] (3) Covering the adhesive backing layer on the film obtained in step (2), that is, forming the non-scar regenerative medical dressing with tissue induction function of this embodiment.

Embodiment 2

[0057] A non-scar regenerative medical dressing with tissue induction function for wounds with little exudate, the preparation method of which is as follows:

[0058] (1) Dissolve degradable polyurethane in chloroform solution to make a 15% solution, and use electrospinning technology to spin a film with a pore size of 10-150 μm and a thickness of 0.05-0.1 mm, and evenly coat a layer of poly Lysine PU (prepared into 1% hydrogel for later use), which is the absorbable medical film;

[0059] (2) The adhesive backing layer is covered on the absorbable medical film obtained in step (1), that is, the non-scar regenerative medical dressing with tissue induction function of this embodiment is formed.

Embodiment 3

[0061] A non-scar regenerative medical dressing with tissue induction function for wounds with a lot of exudate, the preparation method of which is as follows:

[0062] (1) Make PLGA (number average molecular weight 50,000, LA:GA=6:4) into a 15% chloroform solution, and use electrospinning technology to spin a membrane with a pore size of 100-300μm and a thickness of 0.2-0.3mm , evenly sprayed with silicone gel to form an absorbable medical membrane;

[0063] (2) Prepare sodium alginate into a gel, evenly coat the absorbable medical film obtained in step (1), and dry or air dry;

[0064] (3) Choose a suitable breathable membrane as the skin-adhesive backing layer for later use;

[0065] (4) (1) (2) (3) are closely attached in order to form the non-scar regenerative medical dressing with tissue induction function of this embodiment.

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Abstract

The invention provides a scar-free regenerated medicinal dressing with a tissue induction function and a preparation method of the scar-free regenerated medicinal dressing. The scar-free regenerated medicinal dressing comprises absorbable medical membranes, a liquid absorption layer and a back lining layer, wherein the absorbable medical membranes have tissue induction functions and are differentin degradation time; the liquid absorption layer and the back lining layer are sequentially overlapped on the absorbable medical membrane; the absorbable medical membrane is a trauma contact layer incontact with skin. The absorbable medical membranes which have tissue induction functions and are different in degradation time are adopted as a cell crawling bracket layer for covering a wound, cellsslowly crawl and grow through a membrane bracket structure of the dressing in the wound healing process, because of different degradation times of degradable materials, tissue absorption times are different, wound cells have different crawling and growth uniformity degrees, then skin texture like structures are formed, and large-size scars are avoided.

Description

technical field [0001] The invention belongs to the technical field of medical dressings, and specifically relates to a non-scar regenerative medical dressing with tissue induction function and a preparation method thereof. The scar-free regenerative medical dressing with tissue induction function comprises a layer of Absorbable medical membranes with different degradation times for inducing function. In the process of wound healing, cells slowly crawl and grow through the scaffold structure of the absorbable medical membranes. Due to the different degradation times of degradable materials, the tissue absorption time is different. , the crawling growth of wound cells varies in uniformity, thus forming a skin-like texture structure and preventing the formation of large scars. Background technique [0002] In real life, burns, traffic accidents, and mechanical injuries occur from time to time. Mild wounds can be healed with drugs or other means, but in slightly serious cases, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/62A61L15/42A61L15/18A61L15/26
Inventor 不公告发明人
Owner COMSCAFFOLDS NANJING MEDICAL DEVICE CO LTD
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