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Pharmaceutical composition for treating pet skin disease and preparation method thereof

A skin disease and composition technology, which is applied in the field of pharmaceutical composition for treating skin diseases of pets and its preparation, can solve the problem of single treatment range, etc., and achieve the effects of reducing pain, high drug efficacy, and low recurrence rate

Active Publication Date: 2021-02-26
NANJING JINDUN ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The current drugs for the treatment of pet skin diseases have problems such as single treatment range and antibiotic resistance. A drug with good curative effect and reduced fungal and bacterial drug resistance is needed

Method used

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  • Pharmaceutical composition for treating pet skin disease and preparation method thereof
  • Pharmaceutical composition for treating pet skin disease and preparation method thereof
  • Pharmaceutical composition for treating pet skin disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A pharmaceutical composition for treating pet skin diseases, each 100g of the pharmaceutical solution contains: 1g of fluconazole, 30g of C18 trans fatty acid, 1g of baicalein, 1g of clove extract, 1ml of tea tree oil, 1g of hemp, and 5g of glycerin , carbomer 1g, triethanolamine 1.5g, and the balance is distilled water.

[0025] The preparation method of above-mentioned pharmaceutical composition comprises the following steps:

[0026] (1) Take the carbomer of the formula amount to fully expand in an appropriate amount of distilled water, add glycerin and stir evenly, add dropwise triethanolamine, stir until a transparent gel, and obtain gel I;

[0027] (2) Take the baicalein, clove extract, hemp, tea tree oil, and C18 trans fatty acid in the formula amount and mix them in distilled water to obtain mixture II;

[0028] (3) Take the prescribed amount of fluconazole and add distilled water to grind it, and add it to the gel I together with the mixture II, stir and mix e...

Embodiment 2

[0030] A pharmaceutical composition for treating skin diseases of pets, containing in every 100g of the pharmaceutical solution: 2g of fluconazole, 28g of C18 trans fatty acid, 0.5g of baicalein, 3g of clove extract, 3ml of tea tree oil, 0.5g of hemp, Glycerin 6g, carbomer 2g, triethanolamine 1g, and the balance is distilled water.

[0031] The preparation method of above-mentioned pharmaceutical composition comprises the following steps:

[0032] (1) Take the carbomer of the formula amount to fully expand in an appropriate amount of distilled water, add glycerin and stir evenly, add dropwise triethanolamine, stir until a transparent gel, and obtain gel I;

[0033] (2) Take the baicalein, clove extract, hemp, tea tree oil, and C18 trans fatty acid in the formula amount and mix them in distilled water to obtain mixture II;

[0034] (3) Take the prescribed amount of fluconazole and add distilled water to grind it, and add it to the gel I together with the mixture II, stir and m...

Embodiment 3

[0036] A pharmaceutical composition for treating skin diseases of pets, containing: 0.5 g of fluconazole, 35 g of C18 trans fatty acid, 3 g of baicalein, 2 g of clove extract, 0.5 ml of tea tree oil, 2 g of hemp in every 100 g of the pharmaceutical solution, Glycerin 4g, carbomer 3g, triethanolamine 2g, and the balance is distilled water.

[0037] The preparation method of above-mentioned pharmaceutical composition comprises the following steps:

[0038](1) Take the carbomer of the formula amount to fully expand in an appropriate amount of distilled water, add glycerin and stir evenly, add dropwise triethanolamine, stir until a transparent gel, and obtain gel I;

[0039] (2) Take the baicalein, clove extract, hemp, tea tree oil, and C18 trans fatty acid in the formula amount and mix them in distilled water to obtain mixture II;

[0040] (3) Take the prescribed amount of fluconazole and add distilled water to grind it, and add it to the gel I together with the mixture II, stir...

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Abstract

The invention relates to a pharmaceutical composition for treating skin diseases of pets. Each 100g of the pharmaceutical solution contains: 0.5-3g of fluconazole, 25-35g of C18 trans fatty acid, 0.5-3g of baicalein, and 0.5-3g of clove extract , tea tree oil 0.5‑3ml, hemp 0.5‑2g, glycerin 4‑6g, carbomer 0.2‑3g, triethanolamine 1‑2g, and the balance is distilled water. The pharmaceutical composition prepared by the invention has good drug efficacy, reduces the time for treating pet skin diseases, and has low recurrence rate.

Description

technical field [0001] The invention belongs to the technical field of dermatological medicines, and in particular relates to a pharmaceutical composition for treating skin diseases of pets and a preparation method thereof. Background technique [0002] Pet dermatosis is a kind of contact disease. The fungi that infect the skin mainly include Microsporum canis, Microsporum gypsumoid and Trichophyton spp., and the bacteria mainly include Staphylococcus aureus, Escherichia coli, Streptococcus and so on. The disease has the characteristics of stubborn condition, long treatment time, and high recurrence rate. The clinical symptoms are mainly manifested as different degrees of desquamation, depilation, and scab. Harmful to the health of pets. Due to the complex etiology of the disease clinically, mixed infections often occur, and only a few antibiotics used for treatment have good effects on bacteria and fungi, and the use of antibiotics is prone to drug resistance. However, na...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/61A61K9/06A61P17/00A61P31/10A61P31/04A61P33/14A61P31/02A61K31/4196A61K31/352A61K31/20
CPCA61K9/0014A61K9/06A61K31/20A61K31/352A61K31/4196A61K36/60A61K36/61A61K47/32A61K2300/00
Inventor 冯秀娟王智群顾劲乔李忠生谢伟东冒勇
Owner NANJING JINDUN ANIMAL PHARMA
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