Animal bound type acute anxiety model

Abstract

The invention discloses an animal bound type acute anxiety model and belongs to the technical field of animal behavior research, and the model is designed for solving a problem of a poor binding effect of an animal to be tested of an existing device. The animal bound type acute anxiety model comprises a binding plate and an upper cover which is detachably fastened on the binding plate, and a cavity for containing the animal to be tested is formed between the upper cover and the binding plate after fastening. A connection structure is arranged between the upper cover and the binding plate, and the connection structure binds the upper cover and the binding plate when the upper cover covers the binding plate. The animal bound type acute anxiety model has a good animal binding effect, a purpose of binding the animal to be tested such as a rat to establish an acute anxiety model in a behavioral experiment is realized, the model is efficient, convenient, safe and sanitary, an obtained experiment result has high accuracy, and the application range is wide.

Description

technical field [0001] The invention relates to the technical field of animal behavior research, in particular to an animal-bound acute anxiety model. Background technique [0002] At present, the research on the mechanism of anxiety and the development of treatment technology mainly rely on the establishment of effective animal models, among which the restraint acute anxiety model is a relatively main type. [0003] The existing bondage acute anxiety model is to drill a vent hole on the wall of a plastic centrifuge tube with a capacity of 50ml, put the experimental mouse into the centrifuge tube, tighten the bottle cap, let it rest for 15-60 minutes, and take out the experimental mouse Make observations or measure various metrics. [0004] The defects of this model are: 1. The movement of the experimental mouse in the centrifuge tube will cause the centrifuge tube to shake or roll, which will cause the experimental mouse to have an additional sense of dizziness and reduce ...

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Problems solved by technology

[0004] The defects of this model are: 1. The movement of the experimental mouse in the centrifuge tube will cause the centrifuge tube to shake or roll, which will cause the experimental mouse to have an additional sense of dizziness and reduce the accuracy of the output results of the anxiety level; 2. Experimental mice often produce excrement in the centrifuge tube. These excrement are easy to adhere to the body of the experimental mouse, which not only pollutes the experimental environment, causes the gas breathed by the experimental mouse to be very turbid, but also causes the experimental mouse to breathe. The discomfort of the mice, except the anxiety response caused by restraint pressure, greatly affected the follow-up experiments; 3. The specifications of the centrifuge tubes were the same, but there were individual differences in the physique of the experimental mice, which caused each experimental mouse to be affected. 4. There is a certain space for the experimental mice to move in the centrifuge tube, and some experimental mice will take the opportunity to eat the wall of the centrifuge tube, which is not conducive to the recycling of the model. , the physiological health of experimental mice, and the continuity of subsequent experiments

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