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Application of trepang extract in products for preventing and treating depression

An extract, depression technology, applied in the application field of sea cucumber extract in the prevention and treatment of depression products

Inactive Publication Date: 2017-10-17
山东圣洲海洋生物科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It can be seen that there is no use of sea cucumber extract as an active ingredient in the treatment or prevention of depression in the prior art

Method used

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  • Application of trepang extract in products for preventing and treating depression
  • Application of trepang extract in products for preventing and treating depression

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Sea cucumber extract of the present invention, preparation method is as follows:

[0032] 1) Fresh and live sea cucumbers are screened and cleaned by digging the intestines;

[0033] 2) Low-temperature ultrafine pulverization and homogenization of sea cucumbers:

[0034] 4°C low-temperature ultrafine pulverization and homogenization treatment for 80 minutes. After pulverization, the particle size of the sea cucumber particles is 15 μm, and the sea cucumber homogenate liquid is obtained; the particle size of the sea cucumber particles can be adjusted according to the change of the homogenization treatment time. Small, the largest particles can not exceed 25μm, the smallest can be 10μm.

[0035] 3) Composite low-temperature enzymatic hydrolysis:

[0036] Mix the low-temperature protease and amylase at a weight ratio of 2:1, add them to the sea cucumber homogenate obtained in step 2), the weight ratio of the total weight of low-temperature protease and amylase to the sea...

Embodiment 2

[0039] Compared with embodiment 1, this implementation changes temperature and processing time in step 2):

[0040] 2) Low-temperature ultrafine pulverization and homogenization of sea cucumbers:

[0041] 2°C low-temperature ultrafine pulverization and homogenization treatment for 90 minutes, the particle size of the pulverized sea cucumber particles is 10 μm, and the sea cucumber homogenate is obtained;

[0042] The rest of the steps are the same, and the water-soluble sea cucumber extract is also obtained.

Embodiment 3

[0044] Compared with Example 1, this implementation changes the consumption of enzyme in step 3):

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PUM

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Abstract

The invention belongs to the field of drugs and health-care foods, and relates to an application of a trepang extract in products for preventing and treating depression. The effective component of the products for preventing and treating depression is the trepang extract. The invention discloses a new purpose of the trepang extract for effectively resisting the depression, and a new field is developed for the clinical application of new medical or health-care functions of trepang. Classical depression resistant animal model test results prove that a trepang enzymolysis extract can obviously shorten the dead time in a mouse forced swimming test, so that the trepang enzymolysis extract has good depression resisting effect, is obvious in the efficacy of preventing, conditioning and treating the depression, is free from adverse effects of conventional depression resistant drugs, as a natural marine resource extract, and has favorable application prospects.

Description

technical field [0001] The invention belongs to the field of medicines and health food, and relates to the application of sea cucumber extracts in preventing and treating depression products. Background technique [0002] Depression is an affective mental disorder characterized by emotions such as sadness, despair, and depression. Patients often have low self-esteem, self-blame, and self-guilt, and may have suicidal tendencies. According to the survey results of the National Center for Disease Control and Prevention in 2011, the prevalence of depression in my country is 15-20‰, the number of patients has exceeded 100 million, and the incidence rate is showing a clear upward trend. About 1 million people die from suicide every year in the world, while 250,000 people die from suicide in my country, and 2 million people attempt suicide. Therefore, 1 / 4 of the world's annual suicide deaths are concentrated in China. According to the research results of the Social and Economic Bu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/10A61K35/616A61P25/24
CPCA23L33/10A23V2002/00A61K35/616
Inventor 张楠秦德文
Owner 山东圣洲海洋生物科技股份有限公司
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