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Processing technology method for preparing radix rehmanniae preparata through repetitive steaming and airing

A technology of nine-steaming-nine-fabrication and nine-steaming-nine-fabrication technology, applied in the field of traditional Chinese medicine processing, can solve the problems of increasing active ingredients, decreasing toxic ingredients, complicated processes, etc.

Inactive Publication Date: 2017-09-29
安徽华善堂中药饮片有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The methods of processing rehmannia glutinosa are recorded in different documents, such as "steaming three or five times", "steaming nine times and making nine times", etc., but most of them are processed according to experience, and the optimal processing method cannot be found yet. Although the requirements can all meet the standard of "light and black as lacquer, sweet as candy", there are differences in medicinal efficacy, which directly affects the curative effect of processed rehmannia glutinosa.
The ancients discovered through clinical practice that only nine times of steaming and nine times of rehmannia can fully remove its coldness and turn it into a warm medicine, and its effect of nourishing kidney and blood can be manifested. Therefore, three or five times of steaming cannot achieve the medicinal effect.
[0005] In the processing technology of Rehmannia glutinosa, although the conventional nine-steaming and nine-making process meets the requirements in terms of appearance and color, due to its complicated process, various conditions, and high cost, and the processing process is mainly based on the experience of clinical pharmaceutical workers, it is very random. Poor processing effect is the most likely to occur, the increase of active ingredients and the reduction of toxic components can not be optimal, therefore, it is not a mainstream processing technology, but it is precisely because of this fine processing method, once The conditions are suitable, and the processed rehmannia glutinosa is extremely effective

Method used

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preparation example Construction

[0046]In the preparation process of processed rehmannia glutinosa, temperature, pressure, and the consumption of yellow rice wine are the three most important conditional factors. A large number of orthogonal experiments of the present invention show that temperature is the most important factor affecting the efficacy and quality of processed rehmannia glutinosa. To obtain The optimal temperature range for nine-steamed and nine-processed Rehmannia glutinosa is 130°C to 150°C, the optimum temperature is 140°C, the pressure is 0.2Mpa to 0.4Mpa, the optimum pressure is 0.3Mpa, and the ratio of raw rehmannia to rice wine is 3:1~ 2:1 is suitable, we choose 2:1 as the optimal ratio. We analyze the optimal preparation conditions. If the temperature is lower than 130°C, the rehmannia glutinosa will not be easily steamed, and the steaming time will be prolonged. In addition, the microbial control is poor. If the temperature is higher than 150°C, the rehmannia glutinosa will be easily st...

Embodiment 9

[0099] Example Nine Steams and Nine Preparations of Rehmannia glutinosa

[0100] Processed medicine: raw rehmannia decoction pieces

[0101] Yellow rice wine should be old rice wine more than 5 years old, its divergent property is weakened, and its warming and tonic property is strengthened, so steaming Rehmannia glutinosa with aged rice wine is selected to make the warming and tonic effect of Rehmannia glutinosa stronger. If the rice wine is made of old rice wine more than 5 years old, this effect cannot be achieved if the rice wine is selected from the factory. The warming and tonic function of Rehmannia glutinosa is very weak.

[0102] Select 600g of raw rehmannia, implement the "Standard Operating Procedures for Clean Selection Posts", pick out impurities from the raw rehmannia, put them in a clean turnover container, weigh, slice, and the thickness is between 25 and 30mm.

[0103] Implement the "Standard Operating Procedures for Medicine Washing Posts" and "Standard Oper...

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Abstract

The invention provides an optimum processing technology method for preparing radix rehmanniae preparata through repetitive steaming and airing. Through adjusting a technology index of an existing repetitive steaming and airing process, the processing of the radix rehmanniae preparata is optimized, the medicine quality is favorably improved, the contents of 5-hydroxymethylfurfural (HMF) and hydroxyethyl methylacrylate (HMFA) are the highest, and the medicine effect of the radix rehmanniae preparata is further improved.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine processing, in particular to an optimized processing method of rehmannia glutinosa prepared by steaming nine times and preparing rehmannia glutinosa. Background technique [0002] Rehmannia glutinosa is a plant in the family Scrophulariaceae Rehmannia glutinosa Libosch. of tubers. It was first recorded in "Shen Nong's Materia Medica" and listed as top grade. It has been recorded in successive dynasties and is one of the commonly used traditional Chinese medicines. Dihuang used as medicine is divided into: fresh rehmannia, dried rehmannia, rehmannia glutinosa, raw rehmannia charcoal, rehmannia glutinosa charcoal, etc. After rehmannia glutinosa is processed by different processing methods, its nature, taste and efficacy also change accordingly. Fresh rehmannia glutinosa is cold in nature, sweet and bitter in taste, and is mainly used to clear away heat and promote body flu...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61P13/12A61P7/06A61P1/14A61K125/00
CPCA61K36/804A61K2236/10A61K2236/13A61K2236/17
Inventor 周青明茹慈梁斌范九良孙玉许东亚郭庆
Owner 安徽华善堂中药饮片有限公司
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