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Medicinal dressing with bioactivity and preparation method of medicinal dressing

A bioactive and bioactive ingredient technology, applied in the field of medical dressings, can solve the increasingly high requirements for wound care, can not keep the wound moist, wound adhesion and other problems, to achieve good analgesic effect, promote wound healing, comfort high effect

Active Publication Date: 2017-09-22
GUANGZHOU RAINHOME PHARM&TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, the existing bioactive medical dressings cannot keep the wound moist and delay wound healing; when changing the dressing, it is easy to adhere to the wound, causing pain; it is easy to cause infection and other problems, and cannot meet people's increasing demand for wound care. requirements

Method used

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  • Medicinal dressing with bioactivity and preparation method of medicinal dressing
  • Medicinal dressing with bioactivity and preparation method of medicinal dressing
  • Medicinal dressing with bioactivity and preparation method of medicinal dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1, a kind of medical dressing with biological activity

[0038] Described bioactive medical dressing is made up of following components and parts by weight thereof (every part is 300g):

[0039] 1 part of hyaluronic acid, 2 parts of carbomer, 5 parts of bioactive ingredients, 0.5 part of sodium propylparaben, 8 parts of glycerin, 0.2 part of sodium bisulfite, 3 parts of chitosan oligosaccharide, 0.5 part of triethanolamine and 65 parts of deionized water; the bioactive ingredient is composed of basic fibroblast growth factor, epidermal growth factor and oligopeptide in a weight ratio of 11:9:5; the oligopeptide is composed of tripeptide, tetrapeptide and pentapeptide are composed of 4:9:14 by weight.

[0040] Preparation:

[0041] S1 Take 1 / 4 amount of deionized water, add biologically active ingredients, stir at 2°C, the stirring speed is 600r / min, and the stirring time is 30 minutes to obtain solution A, and place it in a refrigerator at 4°C;

[0042] S2...

Embodiment 2

[0044] Embodiment 2, a kind of medical dressing with biological activity

[0045] Described bioactive medical dressing is made up of following components and parts by weight thereof (every part is 300g):

[0046] 2 parts of hyaluronic acid, 4 parts of carbomer, 10 parts of bioactive ingredients, 1 part of sodium propylparaben, 12 parts of glycerin, 0.4 parts of sodium bisulfite, 8 parts of chitosan oligosaccharide, 1.5 parts of triethanolamine and 80 parts of deionized water; the bioactive ingredient is composed of basic fibroblast growth factor, epidermal growth factor and oligopeptide in a weight ratio of 14:7:3; the oligopeptide is composed of tripeptide, tetrapeptide and pentapeptide are composed of 6:7:12 by weight.

[0047] Preparation:

[0048] S1 Take 1 / 4 amount of deionized water, add biologically active ingredients, stir at 6°C, the stirring speed is 800r / min, and the stirring time is 50 minutes to obtain solution A, and place it in a refrigerator at 4°C;

[0049]...

Embodiment 3

[0051] Embodiment 3, a kind of medical dressing with biological activity

[0052] Described bioactive medical dressing is made up of following components and parts by weight thereof (every part is 300g):

[0053] 1.5 parts of hyaluronic acid, 3.5 parts of carbomer, 7 parts of bioactive ingredients, 0.8 parts of sodium propylparaben, 10 parts of glycerin, 0.3 parts of sodium bisulfite, 6 parts of chitosan oligosaccharide, 1.2 parts of triethanolamine and 72 parts of deionized water; the bioactive component is composed of basic fibroblast growth factor, epidermal growth factor and oligopeptide in a weight ratio of 13:8:4; the oligopeptide is composed of tripeptide, tetrapeptide and pentapeptide are composed of 5:8:13 by weight.

[0054] Preparation:

[0055] S1 Take 1 / 4 amount of deionized water, add bioactive ingredients, stir at 4°C, stirring speed is 720r / min, and stirring time is 45 minutes, to obtain solution A, and place it in a refrigerator at 4°C;

[0056] S2 Add hyal...

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Abstract

The invention belongs to the field of medicinal dressings and in particular relates to a medicinal dressing with bioactivity and a preparation method of the medicinal dressing. The medicinal dressing with the bioactivity comprises the following components in parts by weight: 1-2 parts of hyaluronic acid, 2-4 parts of carbomer, 5-10 parts of bioactivity components, 0.5-1 part of propyl p-hydroxybenzoate, 8-12 parts of glycerin, 0.2-0.4 part of sodium hydrogen sulfite, 3-8 parts of chitosan oligosaccharide, 0.5-1.5 parts of triethanolamine and 65-80 parts of deionized water. The medicinal dressing with the bioactivity, which is provided by the invention, is high in comfort degree, is capable of promoting wound heal, remarkably shortening the wound heal time and preventing adhesion, is painless in dressing change and free of irritation, is capable of preventing bacteria and scar and has multiple effects of excellent bioactivity, efficient bacterial resistance, good pain relieving functions, wound heal promotion and the like, a slightly wet heal environment is created and maintained, wound infection is prevented, and wound adhesion is avoided.

Description

technical field [0001] The invention belongs to the field of medical dressings, and in particular relates to a biologically active medical dressing and a preparation method thereof. Background technique [0002] The skin is an important organ of the human body. It has very important physical, chemical and biological barrier functions. It plays a role in preventing the loss of water and electrolytes and other substances, as well as immune and sensing functions. It plays a role in maintaining the stability of the internal environment and preventing microbial invasion. very important role. Skin damage caused by trauma, burns, and skin ulcers will cause a series of problems in the body, such as bacterial infection, increased metabolism, excessive loss of water and protein, endocrine and immune system dysfunction, etc., which may be life-threatening in severe cases. Therefore, after skin injury, it is usually necessary to use a skin substitute medical dressing to protect the wou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/00A61L26/0004A61L26/0014A61L26/0023A61L26/0047A61L26/0061A61L26/0066A61L2300/252A61L2300/402A61L2300/404A61L2300/412A61L2300/414C08L89/00C08L5/08C08L33/00
Inventor 车七石
Owner GUANGZHOU RAINHOME PHARM&TECH CO LTD
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