Method for extracting toddalolactone from radix zanthoxyli traditional Chinese medicine toothpaste

Abstract

The invention discloses a method for extracting toddalolactone from radix zanthoxyli traditional Chinese medicine toothpaste. The method has the advantages of simplicity and convenience for operation, rapidness, accuracy, less interference, relatively good precision and repeatability and the like and belongs to the field of extraction of the toddalolactone. The method disclosed by the invention comprises the following steps: weighing 2g of the radix zanthoxyli toothpaste, mixing the radix zanthoxyli toothpaste with 20ml of 80% methanol and weighing fixed weight M1; stirring for 30min, weighing fixed weight and supplementing the 80% methanol until the weight is M1; carrying out ultrasonic treatment for 30min and cooling; weighing fixed weight and supplementing the 80% methanol until the weight is M1; centrifuging, freezing and standing for 10min; taking 1.5mL to 2mL of supernatant and centrifuging for 5min; filtering to obtain the toddalolactone. The method disclosed by the invention can provide an experimental basis for determining the content of the toddalolactone in the radix zanthoxyli traditional Chinese medicine toothpaste.

Description

technical field [0001] The invention belongs to the field of extracting lianmianzhen, in particular to a method for extracting lianmianzhen from toothpaste, a traditional Chinese medicine of liangmianzhen. Background technique [0002] Liangmianzhen is the dried root of Zanthoxylum nitidum (Roxb.) DC., a Rutaceae plant. It can promote blood circulation and remove blood stasis, promote qi and relieve pain, dispel wind and collaterals, detoxify and reduce swelling. Do not overdose [1] , the variant of Maoliangmianzhen [2] , LMZ medicinal materials are different from Mao LMZ in terms of chemical composition and content. Maoliangzhensu, also known as Feilongzhang blood lactone, is a unique component of Maoliangzhen and Feilongzhang Xuegen; Lianmianzhen chloride is one of the main active ingredients of Liangmianzhen; it exists in medicinal materials Liangmianzhen, Maoliangmianzhen and Feilongzhang in the blood, but the content is different among the three [3-5] . "Chinese Pha...

AI Technical Summary

Problems solved by technology

[0006] At present, the quality control indicators of LMZ have not been perfected, and the quality of LMZ herbs used in the preparation of LMZ toothpaste may vary. However, the formulation process of LMZ toothpaste is strictly kept secret, and there is no relevant report on its quality standard. Therefore, the selection of the raw material drug LMZ will also affect the content and authenticity of the effective components of LMZ toothpaste.

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