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Application and preparing method of trametes robinioplila alcohol extract

A technology of Huaier alcohol and Huaier, which is applied in the direction of drug combination, antineoplastic drugs, medical raw materials derived from fungi, etc.

Inactive Publication Date: 2017-07-25
ZHEJIANG CHINESE MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, the research on Huaier has mainly focused on the resistance of Huaier granules or extracts to tumor cells in recent years. There are few reports on the separation and detailed research of Huaier extraction methods and chemical components. Most studies focus on Its crude extract Huaierqing paste, Huaierqing paste is the hot water extract after the fermentation of Huaier fungus, which contains polysaccharides, proteins, alkaloids and other organic components and more than 10 kinds of mineral elements. polysaccharide protein

Method used

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  • Application and preparing method of trametes robinioplila alcohol extract
  • Application and preparing method of trametes robinioplila alcohol extract
  • Application and preparing method of trametes robinioplila alcohol extract

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Experimental program
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Embodiment

[0031] Taking the extraction rate of total flavonoids as the index, through single factor investigation and orthogonal experiment, the optimal extraction process of Huaier alcoholic extract was determined.

[0032] 1. Single factor investigation

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PUM

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Abstract

The invention discloses application and a preparing method of trametes robinioplila alcohol extract. The trametes robinioplila alcohol extract can be applied to preparation of anti-tumor drugs. It is found that the trametes robinioplila alcohol extract has a remarkable stomach cancer BGC823 cell and colon cancer cell HCT116 proliferation inhibiting effect, meaning that the trametes robinioplila alcohol extract has an anti-tumor function. On this basis, medicinal components of trametes robinioplila are further developed and utilized.

Description

technical field [0001] The invention relates to an active ingredient of a traditional Chinese medicine, in particular to an application and a preparation method of an alcohol extract of Huaier. Background technique [0002] Huaier is an important folk medicinal fungus in my country. Huaier is the dry fruiting body of Trametesrobiniophila Murr., a fungus of the Polyporaceae family. , Shandong, Hebei and other places. "Newly Revised Materia Medica" records: Huai Er, the fungus on this pagoda tree, should be as firm as mulberry. Mulberry, Sophora japonica, Chu, elm, and willow are the five ears, and the soft ones can be eaten. People with Chu ears often eat them, and Huaier treats hemorrhoids. It can be seen from this that the hard Huaier used for medicine should not be used as edible fungus. The cap of Trametes sophoraerum is semicircular, like an ear, and it grows on the ancient Chinese pagoda tree, so it was called "Huaier" in ancient times. Because the whole fruiting body...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/07A61P35/00
Inventor 程向东黄挺黄绳武
Owner ZHEJIANG CHINESE MEDICAL UNIVERSITY
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