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Preservation liquid of pathological tissue sample

A tissue specimen and preservation solution technology, applied in the field of preservation solution of pathological tissue specimens, can solve the problems of mildew, specimen hardening, yellowing, etc., and achieve the effect of lasting effect, reducing burden and reducing cost

Inactive Publication Date: 2017-07-25
GUILIN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the specimens preserved in formaldehyde solution for a long time will have mildew, yellowing, and hardening of the specimens.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A preservation solution for pathological tissue specimens, which is prepared by mixing the following raw materials in proportions by weight:

[0026] Potassium sorbate 2g, industrial ethanol 10g, glycerin 1g, glutaraldehyde 2g, sodium chloride 8.5g, nano silver 0.6g, citric acid 10g, water 60g.

[0027] The mass fraction of glutaraldehyde is 50%.

Embodiment 2

[0029] A preservation solution for pathological tissue specimens, which is prepared by mixing the following raw materials in proportions by weight:

[0030] Potassium sorbate 3.5g, industrial ethanol 15g, glycerin 2 parts, glutaraldehyde 2.5g, sodium chloride 9g, nano silver 0.8g, citric acid 15g, water 80g.

[0031] The mass fraction of glutaraldehyde is 51%.

Embodiment 3

[0033] A preservation solution for pathological tissue specimens, which is prepared by mixing the following raw materials in proportions by weight:

[0034] Potassium sorbate 5g, industrial ethanol 20g, glycerin 3g, glutaraldehyde 3g, sodium chloride 9.5g, nano silver 1g, citric acid 20g, water 100g.

[0035] The mass fraction of glutaraldehyde is 52%.

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PUM

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Abstract

The invention discloses a preservation liquid for a pathological tissue sample. The preservation liquid is prepared through mixing by weight, 2-5 parts of potassium sorbate, 10-20 parts of industrial ethanol, 1-3 parts of glycerol, 2-3 parts of glutaraldehyde, 8.5-9.5 parts of sodium chloride, 0.6-1 part of nano-silver, 10-20 parts of citric acid and 60-100 parts of water. The sample preservation liquid is a colorless and transparent liquid, has no irritating odor and has excellent sterilization and mildew inhibition performances; the preservation liquid can effectively maintain the tissue form and color and the color of a protozoa sample, contains no volatile substances, has a lasting effect, and can effectively reduce the cost; and the preservation liquid contains no poisonous or harmful substances, is green and environmentally-friendly, and reduces the environment burden.

Description

technical field [0001] The invention relates to the technical field of pathological tissue preservation, in particular to a pathological tissue specimen preservation solution. Background technique [0002] From the operating room to the pathology department, laboratory surgery, tissue biopsy, histopathology department, gastroscopy department, etc., it is necessary to use specimen preservation solution for fixing, storing and retaining samples of tissues or cells. The existing preservation solution is mainly Fu formalin preservation solution. Formalin specimen preservation solution has a good fixation effect, which is due to the large amount of formaldehyde combined with the functional groups of the specimen protein, and after long-term storage, it further polymerizes to form paraformaldehyde. This process makes it form a moderate cross-link between protein peptide chains, which can not only kill bacteria, but also maintain the tissue shape of the specimen. However, formald...

Claims

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Application Information

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IPC IPC(8): A01N1/02
CPCA01N1/021
Inventor 陆毓孙莉曾思恩陆明深
Owner GUILIN MEDICAL UNIVERSITY
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