Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Classification method, device and system based on platelet differentially expressed gene marker

A technology of differentially expressed genes and classification methods, applied in the computer field, can solve problems such as limited application, insufficient accuracy of unknown individual classification results, poor sensitivity, etc., and achieve the effects of removing noise information, high data processing efficiency, and accurate classification and discrimination

Inactive Publication Date: 2017-06-13
张渠
View PDF6 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the existing identification methods of differentially expressed gene markers have poor sensitivity, resulting in insufficient accuracy of classification results of unknown individuals based on differentially expressed gene markers, resulting in limited subsequent applications

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Classification method, device and system based on platelet differentially expressed gene marker
  • Classification method, device and system based on platelet differentially expressed gene marker
  • Classification method, device and system based on platelet differentially expressed gene marker

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0037] Embodiments of the technical solutions of the present invention will be described in detail below in conjunction with the accompanying drawings. The following examples are only used to illustrate the technical solution of the present invention more clearly, so they are only examples, and should not be used to limit the protection scope of the present invention.

[0038] It should be noted that, unless otherwise specified, the technical terms or scientific terms used in this application shall have the usual meanings understood by those skilled in the art to which the present invention belongs.

[0039] A classification method based on platelet differentially expressed gene markers provided by the embodiment of the present invention, the method includes:

[0040] Information obtaining step: obtaining the sequencing read sequence of the target individual;

[0041] Analysis and comparison step: comparing the sequencing read sequence with the pre-acquired human genome, resp...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the computer technology field, and provides a classification method, device and system based on a platelet differentially expressed gene marker. The method comprises the steps that a sequencing reading sequence of a target sample platelet transcriptome is acquired; a comparison result between the sequencing reading sequence and a human genome is acquired according to a suffix array search algorithm and a sequence splitting / searching / extending strategy; a gene expression estimation value is determined according to a maximum likelihood method; a gene expression difference of a positive sample set and a negative sample set is acquired through a linear statistical method; a hyperplane expression is constructed according to the positive sample set and the negative sample set; an entity gene expression estimation values are classified according to the hyperplane expression, the entity gene expression estimation values and a support vector machine principle. According to the classification method, device and system based on the platelet differentially expressed gene marker, the differentially expressed gene marker can be quickly and accurately identified, and the classification precision of corresponding individuals of a group is improved.

Description

technical field [0001] The invention relates to the field of computer technology, in particular to a classification method, device and system based on platelet differentially expressed gene markers. Background technique [0002] The transcriptome is a collection of messenger ribonucleic acid produced by all genes in a cell, which plays an important role in the normal operation of cells. In humans or other organisms, almost all cells contain the same set of genes, but their expression patterns are closely related to the type of cells, the organ tissue they belong to, the physiological conditions they live in, or the individual samples they live in, so , by interpreting and comparing the information provided by the transcriptome, researchers are able to identify differentially expressed gene signatures between two groups of individuals with different attributes, and based on the expression patterns of differentially expressed gene signatures, perform research on unknown cells ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/24
CPCG16B40/00
Inventor 张渠周智
Owner 张渠
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com