Cell-biological scaffold complex and 3D printing forming method thereof

Abstract

The invention discloses a cell-biological scaffold complex and a 3D printing forming method thereof. The cell-biological scaffold complex comprises a biological scaffold and a cell-biological gel suspension arranged on the biological scaffold, wherein the biological scaffold comprises a one of or a combination of several of a biological macromolecular material, a natural biological material and an inorganic material, the biological macromolecular material comprises one of or a combination of several of calcium phosphate, polycaprolactone, polytetrafluoroethylene and lactic acid-hydroxyacetic acid copolymer, the natural biological material comprises one of or a combination of two of gelatin and sodium alginate, the inorganic material comprises one of or a combination of several of calcium sulfate, boron silicate and nano hydroxylapatite, the cell-biological gel suspension comprises cell and biological gel, and the cell is a bone cell or a corneal stroma. By adopting the cell-biological scaffold complex and the 3D printing forming method, a complexing efficiency of the cell and the biological gel suspension can be increased, the loss or dropping of a great amount of cells is avoided, the preparation process is simple, and the use is convenient.

Description

technical field [0001] The invention relates to the field of biotechnology, in particular to a cell-biological scaffold complex and a 3D printing forming method thereof. Background technique [0002] Tissue defect repair and organ transplantation are one of the greatest breakthroughs in the history of medicine in the 20th century. At present, nearly one million patients in the world who were once shrouded in the shadow of death have obtained a new life through organ transplantation, but they cannot perform due to lack of donor organs. There are tens of millions of patients who die from organ transplantation, and hundreds of millions of patients who need tissue defect repair. Therefore, some people say that the 21st century is the century of tissue repair and organ transplantation. The emergence of 3D printing technology has made millions of people who need tissue repair Patients with prosthetics and organ transplants are given hope of healing and rebirth. [0003] The paten...

AI Technical Summary

Problems solved by technology

[0004] Based on the technical problems existing in the background technology, the present invention proposes a cell-biological scaffold complex and its 3D printing forming method, which is used to solve the problem of low composite efficiency of biological scaffolds and cells, easy loss of cells or a large number of cells, and long culture time required The problem