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Online detector and applications thereof

A detector and detector technology, which is applied in the field of online detectors, can solve problems such as time-consuming, achieve fast detection speed and improve detection efficiency

Active Publication Date: 2017-05-10
DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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  • Abstract
  • Description
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Problems solved by technology

However, as a complex biological sample, blood must be pretreated before chromatographic separation, which makes the above methods time-consuming and mostly offline analysis, which cannot fully meet the needs of clinical anesthesia monitoring.

Method used

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  • Online detector and applications thereof

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Embodiment Construction

[0024] The online detector of propofol in blood adopts the traditional homogeneous field mobility spectrometry, and its structure diagram is shown in figure 1 . This instrument mainly includes the following parts: 1 is the micro sample injector, 2 is the upper partition of the sample injector bracket, 3 is the sample injector bracket, 4 is the rotating turntable with a built-in sampling disk, 5 is the rotary motor, and 6 is the drive. Motor, 7 is the thermal analysis chamber, 8 is the carrier gas inlet of the injector, 9 is the sample gas outlet of the injector, 10 is the inlet of the sample gas entering the transfer tube, 11 is the ionization area of ​​the transfer tube, 12 is the ion gate of the transfer tube, 13 14 is the migration tube grid, 15 is the ion receiving electrode of the migration tube, 16 is the drift gas inlet, and 17 is the gas outlet of the migration tube.

[0025] The micro sample injector 1 takes 10-100uL of blood samples and drops them on the surface of ...

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Abstract

The present invention relates to an online detector, wherein an ion mobility spectroscopy technology is adopted as a basic detection technology, a sample injection rotation disk is controlled by a rotation motor, sample thermal analysis and headspace injection technology are combined, a sample is not subjected to complex pretreatment and is collected to the surface of a sampling sheet, the rotation motor controls the sample injection rotation disk so as to make the sample on the sampling sheet be subjected to continuous sample injection thermal analysis, and the obtained sample enters the detector through carrying with carrier gas so as to be subjected to online detection analysis. According to the present invention, the online detector is used for the continuous online detection of propofol anesthetics in human blood during surgeries so as to guide physicians in clinical administration.

Description

technical field [0001] The invention is based on the ion mobility spectrometry technology, utilizes the working principle of a rotary motor, and combines the sample thermal analysis and headspace sampling technology to design an on-line detector. The detection device and method of the present invention are used for clinical blood concentration analysis of propofol anesthetic in blood, and can guide clinical anesthesiologists to use drugs accurately. Background technique [0002] Rotating electrical machines are divided into three categories: DC motors, three-phase asynchronous motors, single-phase AC motors, etc. The principle of rotation of the DC motor is that the current-carrying conductor rotates under the force of the magnetic field. The rotation of the DC motor is that the magnetic field does not move, and the conductor moves. [0003] Thermal analysis technology is a two-in-one technology: it integrates sampling and concentration, and then transfers the sample from t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/62
Inventor 李海洋李恩有王新李东明鞠帮玉李庆运
Owner DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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