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Pharmaceutical composition for treating chronic laryngitis

A technology for chronic laryngitis and a composition is applied in the field of pharmaceutical compositions for the treatment of chronic laryngitis and preparation thereof, and can solve problems such as objective evaluation affecting the curative effect, insufficient organic coordination, shortening the course of treatment and the like

Inactive Publication Date: 2017-04-26
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to the analysis of TCM literature reports in recent years, the diagnosis and curative effect judging standards of chronic laryngitis are not unified, and there is a lack of objective monitoring indicators and control groups, which affect the objective evaluation of curative effect; Long-term curative effect observation, and the organic cooperation between various therapies is not enough, if combined application, it can better shorten the course of treatment and improve the curative effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1: the pharmaceutical composition for the treatment of chronic laryngitis and preparation method thereof

[0034]The composition and parts by weight of the crude drug of the pharmaceutical composition for treating chronic laryngitis are: moss moss 565g, Dajindao 438g, gingkoxanthin 46g, asiatic acid 35g;

[0035] Preparation:

[0036] (1) According to the ratio of raw materials, take moss moss, Dajindao, ginkgo xanthin and asiatic acid, mix them evenly, use ethanol with a concentration of 27% by weight as a solvent, and extract by warm soaking at 30°C. The number of extractions is 12 times , each extraction time is 49 hours, each solvent dosage is 74 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.09, filters, and extracts A The liquid passes through the LKS05 macroporous adsorption resin column, firstly elutes with water, then elutes the LK...

Embodiment 2

[0039] Embodiment 2: the pharmaceutical composition for the treatment of chronic laryngitis and preparation method thereof

[0040] The composition and parts by weight of the raw material of the pharmaceutical composition for treating chronic laryngitis are: moss moss 562g, Dajindao 440g, gingkoxanthin 42g, asiatic acid 38g;

[0041] Preparation:

[0042] (1) According to the ratio of raw materials, take moss moss, Dajindao, ginkgo xanthin and asiatic acid, mix them evenly, use ethanol with a concentration of 27% by weight as a solvent, and extract by warm soaking at 30°C. The number of extractions is 12 times , each extraction time is 49 hours, each solvent dosage is 74 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.09, filters, and extracts A The liquid passes through the LKS05 macroporous adsorption resin column, firstly elutes with water, then elutes the...

Embodiment 3

[0045] Embodiment 3: the pharmaceutical composition for the treatment of chronic laryngitis and preparation method thereof

[0046] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating chronic laryngitis are: moss moss 568g, Dajindao 436g, gingkoxanthin 48g, asiatic acid 32g;

[0047] Preparation:

[0048] (1) According to the ratio of raw materials, take moss moss, Dajindao, ginkgo xanthin and asiatic acid, mix them evenly, use ethanol with a concentration of 27% by weight as a solvent, and extract by warm soaking at 30°C. The number of extractions is 12 times , each extraction time is 49 hours, each solvent dosage is 74 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.09, filters, and extracts A The liquid passes through the LKS05 macroporous adsorption resin column, firstly elutes with water, then elutes the L...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating chronic laryngitis and a preparation method of the pharmaceutical composition. The pharmaceutical composition provided by the invention is prepared by proportioning the following medicinal raw materials: climacium dendroides web et mohr, ovate neolepisorus herb, bilobetin and asiatic acid, and the pharmaceutical composition can be prepared into various dosage forms in accordance with a conventional preparation process. The pharmaceutical composition is significant in curative effect on treating the chronic laryngitis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating chronic laryngitis and a preparation method thereof. Background technique [0002] Chronic laryngitis, also known as chronic non-specific laryngitis, is a chronic inflammation of the laryngeal mucosa. It is mainly caused by repeated episodes of acute laryngitis that are not treated in time and become chronic, or caused by long-term improper and excessive voice use. It manifests as chronic congestion and swelling of the laryngeal mucosa, lymphocyte infiltration, increased glandular secretion, followed by hyperplasia of connective tissue, mucosal hypertrophy, dilation of blood vessels on the surface of the vocal cords, and subepithelial exudation, etc. In severe cases, there are granular protrusions or polypoid changes on the surface of the mucosa . The main symptoms are hoarseness, short-lasting phonation...

Claims

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Application Information

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IPC IPC(8): A61K36/12A61P11/04A61K36/10A61K31/352A61K31/56
CPCA61K36/10A61K31/352A61K31/56A61K36/12A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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