Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A long afterglow material that can be excited by x-rays and its application

An X-ray and long afterglow technology, applied in the field of biological imaging materials, can solve problems such as poor tissue penetration, and achieve the effect of narrow emission spectrum band, wide application prospect and good photostability

Active Publication Date: 2019-04-23
HEBEI UNIVERSITY
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to provide a long afterglow material that can be excited by X-rays and its application, so as to solve the defects of the existing long afterglow nanomaterials as luminescent materials, mostly in the infrared band, which have poor tissue penetration.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A long afterglow material that can be excited by x-rays and its application
  • A long afterglow material that can be excited by x-rays and its application
  • A long afterglow material that can be excited by x-rays and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] (1) Add 0.005mol NaNO 3、 0.00495mol Y (NO 3 ) 3、 0.00005mol Pr(NO 3 ) 3 Dissolve in 20mL of water, stir evenly to obtain aqueous solution A;

[0032] (2) Dissolve 0.005mol of EDTA-2Na in 30mL of water, stir well to obtain aqueous solution B;

[0033] (3) Add 0.02mol of NH 4 Dissolve F in 10mL of water and stir evenly to obtain aqueous solution C;

[0034] (4) Add aqueous solution B to aqueous solution A, stir for 30 minutes, then add aqueous solution C, and stir to obtain a reaction mixture;

[0035] (5) Put the reaction mixture into a high-pressure reactor, put the high-pressure reactor into a dry box and heat up to 180°C and keep it reacting for 12 hours; after the reaction is completed, let it cool naturally, centrifuge the solution, and dry it to obtain NaY 0.99 f 4 :0.01Pr 3+ Material.

Embodiment 2

[0037] (1) 0.005mol NaNO 3、 0.00495mol Gd(NO 3 ) 3、 0.00005mol Pr(NO 3 ) 3 Dissolve in 20mL of water, stir evenly to obtain aqueous solution A;

[0038] (2) Dissolve 0.005mol EDTA-2Na in 30mL of water, stir well to obtain aqueous solution B;

[0039] (3) Add 0.02mol of NH 4 Dissolve F in 10 mL of water and stir evenly to obtain aqueous solution C;

[0040] (4) Add aqueous solution B to aqueous solution A, stir for 30 minutes, then add aqueous solution C, and stir to obtain a reaction mixture;

[0041] (5) Put the reaction mixture into a high-pressure reactor, put the high-pressure reactor into a drying oven to raise the temperature to 180°C and keep the reaction for 12 hours; after the reaction is completed, cool it naturally, centrifuge the solution, and dry it to obtain NaGd 0.99 f 4 :0.01Pr 3+ Material.

Embodiment 3

[0043] (1) 0.005mol NaNO 3、 0.002475mol Y (NO 3 ) 3、 0.002475molGd(NO 3 ) 3, 0.00005mol Pr(NO 3 ) 3 Dissolve in 20mL of water, stir evenly to obtain aqueous solution A;

[0044] (2) Dissolve 0.005mol EDTA-2Na in 30mL of water, stir well to obtain aqueous solution B;

[0045] (3) Add 0.02mol of NH 4 Dissolve F in 10 mL of water and stir evenly to obtain aqueous solution C;

[0046] (4) Add aqueous solution B to aqueous solution A, stir for 30 minutes, then add aqueous solution C, and stir to obtain a reaction mixture;

[0047] (5) Put the reaction mixture into a high-pressure reactor, put the high-pressure reactor into a drying oven to raise the temperature to 180°C and keep the reaction for 12 hours; after the reaction is completed, cool it naturally, centrifuge the solution, and dry it to obtain Na(YGd) 0.99 f 4 :0.01Pr 3+ Material.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a long-persistence material capable of being excited by X rays. The long-persistence material has the general chemical formula of MxN(1-a-b)Zy:aRe,bLn, wherein M is at least one of Li, Na, K, Rb and Cs, N is at least one of Y, Gd, Al, In, Sc, Ga and Lu, Z is at least one F, Cl, Br and I, Re is at least one of Pr and Ce, Ln is at least one of Mn, Cr, La, Nd, Sm, Eu, Gd, Tn, Dy, Ho, Er, Tm, Yb, Yo and Lu, 0.001<=a<=0.1, 0<=b<=0.05, x is 1 or 3, y is 4 or 6, y is equal to 4 when x is equal to 1, and y is equal to 6 when x is equal to 3. The material can emit light under excitation of the X rays, is long in persistence attenuation time, can be well applied in biological fluorescent labeling imaging, provides more choices for an existing fluorescence imaging application material and has a wide application prospect in biomedical imaging, diagnosing and treating by serving as a novel molecular probe material.

Description

technical field [0001] The invention relates to biological imaging materials and applications, in particular to a long afterglow material that can be excited by X-rays and applications thereof. Background technique [0002] In recent decades, with the continuous development and exploration of life science technology and research, people's research on active species in organisms, in vivo signal transduction, etc. has gradually deepened, and the scope of research has become wider and wider. Bioimaging analysis is the most intuitive analysis and detection method used in live body analysis in existing technologies. At present, the biological probes used for fluorescence imaging analysis are mostly fluorescent materials such as fluorescent dyes and quantum dots. These fluorescent materials provide more convenient and feasible fluorescent probes for in vivo analysis. In recent years, as one of the important members of rare earth luminescent materials, long-lasting nanomaterials h...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C09K11/85C09K11/64C09K11/62
CPCC09K11/7705C09K11/7706C09K11/7773
Inventor 杨艳民张伟魏军杨敬伟
Owner HEBEI UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com