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Medicine composition for treating rheumatoid arthritis and preparation method thereof

A rheumatoid and composition technology, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, can solve problems such as high treatment costs and adverse drug reactions.

Inactive Publication Date: 2017-03-29
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the clinical treatment of this disease is mainly combined drugs, but the treatment cost is expensive, and it also has certain adverse drug reactions.

Method used

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  • Medicine composition for treating rheumatoid arthritis and preparation method thereof
  • Medicine composition for treating rheumatoid arthritis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: The pharmaceutical composition for the treatment of rheumatoid arthritis and its preparation method

[0035] The composition and parts by weight of the raw material of the pharmaceutical composition for treating rheumatoid arthritis are: 126g of Streptococcus miltiorrhiza, 121g of β-ionone 14g, 114g of Potentelic acid 7g,

[0036] Preparation:

[0037] (1) According to the ratio of the raw materials, take the genus chinensis, moss blondii, β-ionone, chrysalis falciparum, and pollenic acid, mix them evenly, use ethanol with a concentration of 32% by weight as a solvent, and heat at 36°C Warm immersion extraction, the number of extractions is 11 times, each extraction time is 57 hours, and the amount of solvent used each time is 42 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to The relative density is 1.06, filtered, the liquid medicine passes through the D35...

Embodiment 2

[0040] Embodiment 2: the pharmaceutical composition for the treatment of rheumatoid arthritis and its preparation method

[0041] The composition and parts by weight of the raw material of the pharmaceutical composition for treating rheumatoid arthritis are: 124g of Streptococcus miltiorrhiza 122g of β-ionone 12g of 118g of Potentelic acid;

[0042] Preparation:

[0043] (1) According to the ratio of the raw materials, take the genus chinensis, moss blondii, β-ionone, chrysalis falciparum, and pollenic acid, mix them evenly, use ethanol with a concentration of 32% by weight as a solvent, and heat at 36°C Warm immersion extraction, the number of extractions is 11 times, each extraction time is 57 hours, and the amount of solvent used each time is 42 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to The relative density is 1.06, filtered, the liquid medicine passes through the D3520...

Embodiment 3

[0046] Embodiment 3: the pharmaceutical composition for the treatment of rheumatoid arthritis and its preparation method

[0047] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating rheumatoid arthritis are: 128g of Streptococcus miltiorrhiza, 120g of β-ionone 16g, 110g of Potentinic acid, 110g of Potentinic acid;

[0048] Preparation:

[0049] (1) According to the ratio of the raw materials, take the genus chinensis, moss blondii, β-ionone, chrysalis falciparum, and pollenic acid, mix them evenly, use ethanol with a concentration of 32% by weight as a solvent, and heat at 36°C Warm immersion extraction, the number of extractions is 11 times, each extraction time is 57 hours, and the amount of solvent used each time is 42 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to The relative density is 1.06, filtered, the liquid medicine pa...

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Abstract

The invention discloses a medicine composition for treating rheumatoid arthritis and a preparation method thereof. The medicine composition is prepared from the raw material medicines of herb of trifid sopubia, pogonatum aloides, beta-ionone, calanthe puberula and tormentic acid in proportion. Various dosage forms can be prepared according to a conventional preparation process, and the effect of treating rheumatoid arthritis is significant.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating rheumatoid arthritis and a preparation method thereof. Background technique [0002] Rheumatoid arthritis (RA) is an autoimmune systemic disease. The main clinical features of patients are chronic, symmetrical and progressive arthritis, accompanied by systemic multisystem involvement. Osteoporosis (OP) is a common complication in the progression and treatment of RA. At present, the clinical treatment of this disease is mainly combined drugs, but the treatment cost is expensive, and it also has certain adverse drug reactions. Rheumatoid arthritis (RA) is a systemic chronic disease of unknown etiology mainly characterized by inflammatory synovitis. The clinical features of the patient are aggressive and multi-joint symmetrical joint inflammation in the small joints of the limbs, often involving other organs and tissu...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P19/02A61P29/00A61K31/56A61K31/12
CPCA61K36/80A61K31/12A61K31/56A61K36/10A61K36/898A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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