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Pharmaceutical composition for treating vitreous opacity and preparation method thereof

A technology of vitreous opacity and composition, which is applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, etc., and can solve the problem of vitreous hyperplasia caused by factors such as cell or inflammatory cell decomposition products, fibrin, and fibroblast hyperplasia Sexual changes, detachment, difficult recovery of visual function, etc.

Inactive Publication Date: 2017-03-29
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If not treated in time, hemorrhage or inflammatory substances may be absorbed delayed, or even not absorbed for a long time, not only cause vision loss, but also cause vitreous hyperplasia due to factors such as red blood cells or inflammatory cell decomposition products, fibrin, and fibroblast proliferation in the vitreous Sexual changes, angiogenesis, hemosiderosis, and some serious complications such as neovascular glaucoma and traction retinal detachment may occur, making it more difficult to restore visual function

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1: the pharmaceutical composition and preparation method thereof for the treatment of vitreous opacity

[0039] The composition and parts by weight of the raw materials of the pharmaceutical composition for treating vitreous opacity are: pokeweed saponin A 24g, Yizhuxiang 358g, purple tuberose 472g, cucurbitacin L18.5g, vernonia phylloxin 15g, and sophorin 2g;

[0040] Preparation:

[0041] (1) Take pokeweed saponin A, Yizhuxiang, purple tuber grass, cucurbitacin L, vernoniarin and sophoridoside according to the proportion of raw materials, mix them evenly, and use ethanol with a concentration of 37.5% by weight as a solvent. 26.5 ℃ warm immersion extraction, the number of extractions is 13 times, each extraction time is 17 hours, and the amount of solvent used each time is 34 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A to recover ethanol , concentrated to a relative density of 1.16, filter...

Embodiment 2

[0044] Embodiment 2: the pharmaceutical composition and preparation method thereof for the treatment of vitreous opacity

[0045] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating vitreous opacity are: pokeweed saponin A 23.5g, Yizhuxiang 360g, purple tuberose 470g, cucurbitacin L19g, vernonia phylloxin 14g, sophorin 3g;

[0046] Preparation:

[0047] (1) Take pokeweed saponin A, Yizhuxiang, purple tuber grass, cucurbitacin L, vernoniarin and sophoridoside according to the proportion of raw materials, mix them evenly, and use ethanol with a concentration of 37.5% by weight as a solvent. 26.5 ℃ warm immersion extraction, the number of extractions is 13 times, each extraction time is 17 hours, and the amount of solvent used each time is 34 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A to recover ethanol , concentrated to a relative density of 1.16, filter...

Embodiment 3

[0050] Embodiment 3: the pharmaceutical composition and preparation method thereof for the treatment of vitreous opacity

[0051] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating vitreous opacity are: pokeweed saponin A 24.5g, Yizhuxiang 356g, purple tuberose 475g, cucurbitacin L18g, vernonia 16g, sophorin 1g;

[0052] Preparation:

[0053] (1) Take pokeweed saponin A, Yizhuxiang, purple tuber grass, cucurbitacin L, vernoniarin and sophoridoside according to the proportion of raw materials, mix them evenly, and use ethanol with a concentration of 37.5% by weight as a solvent. 26.5 ℃ warm immersion extraction, the number of extractions is 13 times, each extraction time is 17 hours, and the amount of solvent used each time is 34 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A to recover ethanol , concentrated to a relative density of 1.16, filtered, the dr...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating vitreous opacity and a preparation method thereof. The pharmaceutical composition is prepared from pokeberry root saponin A, common anotis herb, stenosolenium saxatile roots, cucurbitacine L, vernomenin and sophoricoside in a matching mode, various preparations can be prepared according to a conventional preparation process, and the treatment effect on vitreous opacity is remarkable.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for treating vitreous opacity and a preparation method thereof. Background technique [0002] The vitreous body is a transparent jelly-like tissue, the main component is a network frame composed of collagen fibers, which is filled with hyaluronic acid adsorbing molecules, and the field of vision is clear and flawless, ensuring the acuity of vision. Once an opaque body other than the normal structure appears in the vitreous, it can cause vitreous opacity. Vitreous opacity is a common eye disease in ophthalmology. Vitreous opacity is mostly caused by hemorrhage (ocular trauma, diabetes, hypertension, retinal periphlebitis, rhegmatogenous retinal detachment, etc.), inflammation (uveitis, endophthalmitis, etc.) and degeneration (such as medium to high myopia) and many other reasons cause. If not treated in time, hemorrh...

Claims

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Application Information

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IPC IPC(8): A61K36/74A61P27/02A61K31/366A61K31/704A61K31/575A61K31/7048
CPCA61K31/366A61K31/575A61K31/704A61K31/7048A61K36/30A61K36/74A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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