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A compound traditional Chinese medicine for treating fatty liver

A compound traditional Chinese medicine, fatty liver technology, applied in the direction of pharmaceutical formulations, drug combinations, medical preparations containing active ingredients, etc., can solve the problems of liver and kidney toxicity, long-term use of chemical drugs, clinical application limitations, etc., to reduce the content of TG Effect

Active Publication Date: 2019-08-13
XIAMEN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, modern medicine mostly uses exercise and weight loss as the main treatment methods, and chemical drugs need to be taken for a long time, and even adverse reactions such as liver and kidney toxicity may occur, so the clinical application is limited

Method used

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  • A compound traditional Chinese medicine for treating fatty liver
  • A compound traditional Chinese medicine for treating fatty liver

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Embodiment Construction

[0015] In order to further describe the present invention in detail, specific examples are given, but only to illustrate the present invention, not to limit the scope of the present invention. details as follows:

[0016] 1 material

[0017] 1.1 Experimental animals Thirty SD male rats, clean grade, about 200 g, were provided by the Shanghai Experimental Animal Center of the Chinese Academy of Sciences.

[0018] 1.2 Drugs and reagents TG kits, ALT kits, and AST kits were purchased from Nanjing Jiancheng Institute of Bioengineering.

[0019] 1.3 High-fat feed Composition of high-fat feed: 83.25% basic feed, 10% lard, 1.5% cholesterol, 0.2% sodium deoxycholate, 5% sugar, 0.05% propylthiouracil, provided by Suzhou Shuangshi Animal Feed Co., Ltd. .

[0020] 2 methods

[0021] 2.1 Modeling and grouping medication From the day of modeling, according to the random number table, SD rats were divided into normal group, model group and 6 each of the group of the present invention, a...

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Abstract

The invention provides a compound traditional Chinese medicine for treating fatty liver, and relates to compound traditional Chinese medicine. The compound traditional Chinese medicine for treating the fatty liver is prepared from, by mass, 0.5-1 part of spina gleditsiae, 0.5-1 part of unprocessed rhizoma atractylodis macrocephalae and 1-2 parts of herba artemisiae scopariae. The compound traditional Chinese medicine for treating the fatty liver can adopt preparations suitable for being orally administered and can be selected from one of tablets, capsules, soft capsules, granules, dropping pills, dispersible tablets, orally disintegrating tablets, pills, oral liquid and the like. The compound traditional Chinese medicine for treating the fatty liver can be taken after decocting and can also be taken after being extracted with water or ethyl alcohol. The compound traditional Chinese medicine has the functions of clearing heat, eliminating dampness, activating blood, dispersing blood stasis, strengthening the spleen and benefiting qi. The content of TG in high fat diet-induced fatty liver rat liver tissue can be decreased, rising of serum ALT and AST activity is inhibited, the effect of treating the fatty liver is achieved, and the compound traditional Chinese medicine can be used for preparing drugs for treating the fatty liver.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine, in particular to a compound traditional Chinese medicine for treating fatty liver. Background technique [0002] In recent years, with the changes in dietary structure and lifestyle, the incidence of fatty liver in my country has been increasing and tends to be younger. As an important factor in the occurrence and development of chronic liver diseases such as liver fibrosis, cirrhosis, and liver cancer, it is very likely to become The number one liver disease in China. At present, modern medicine mostly uses exercise and weight loss as the main treatment methods, and chemical drugs need to be taken for a long time, and even adverse reactions such as liver and kidney toxicity may occur, so the clinical application is limited. The traditional Chinese medicine compound has multi-channel and multi-link pharmacological effects, which is the superiority of its overall concept, and has become a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/483A61P1/16
CPCA61K36/28A61K36/284A61K36/483A61K2236/33A61K2236/331A61K2300/00
Inventor 陈少东梁惠卿
Owner XIAMEN UNIV
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