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Honeysuckle dew containing both chlorogenic acid and volatile oil components and preparation method thereof

A technology of honeysuckle dew and volatile oil, which is applied to medical preparations containing active ingredients, functions of food ingredients, food ingredients, etc., can solve the problems of large volatilization loss of aromatic substances, poor taste, loss of chlorogenic acid, etc., to ensure clinical Efficacy, good color and good taste

Active Publication Date: 2019-12-31
HUBEI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the traditional decoction method can basically maintain the clinical efficacy, but because of the large loss of aromatic substances, the honeysuckle characteristic aroma of the obtained honeysuckle dew is not strong, the taste is poor, and part of the chlorogenic acid is lost after long-term high-temperature decoction
With the advancement of technology, manufacturers blindly pursue the senses and flavors, ignoring the internal quality. Now most of them use the distillation method to prepare honeysuckle dew. The distillation method better maintains the characteristic aromatic substances in honeysuckle. The flavor of honeysuckle dew is outstanding, the color is good, and the taste is good. The honeysuckle dew produced by this method does not contain chlorogenic acid at all, and there is no guarantee that the honeysuckle dew has antiviral, antibacterial, anti-inflammatory, and antitumor effects.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] 1. Take 10 kg of honeysuckle medicinal material (food material), which is identified as the flower bud of Lonicera Lonicerae. Infiltrated with 1.0% NaCl solution for 4 hours, washed and dried by centrifuge for extracting active ingredients.

[0032] 2. Use 50L of pure water and hydrochloric acid to adjust the pH value of the infiltrated honeysuckle medicinal material (ingredients) to 3.5, use low temperature (30°C) countercurrent extraction, cool the extract, let it stand for 4-8 hours and filter, collect the filtrate A and save it for later use .

[0033] 3. Using the medicinal dregs collected after countercurrent extraction as raw materials, use high-temperature continuous thermal extraction (105°C) to collect volatile oil fractions, rapidly cool, let stand for 4 hours, filter, and collect filtrate B for storage for later use.

[0034] 4. The obtained filtrate A and the above-mentioned obtained filtrate B are compatible according to the ratio of the crude drug amount...

Embodiment 2

[0039] 1. Take 10 kilograms of honeysuckle medicinal materials (foodstuffs), which are identified as flower buds of Lonicera japonica. Soaked in a solution containing 2.0% NaCl for 8 hours, washed and dried by a centrifuge to extract active ingredients.

[0040] 2. Use 100L of pure water and hydrochloric acid to adjust the pH value of the infiltrated honeysuckle medicinal material (ingredients) to 6.5, use low temperature (60°C) countercurrent extraction, cool the extract, let it stand for 8 hours and filter, collect the filtrate A and save it for later use.

[0041] 3. Using the medicinal dregs collected after countercurrent extraction as raw materials, use high-temperature continuous thermal extraction (115°C) to collect volatile oil fractions, rapidly cool, let stand for 4 hours, filter, and collect filtrate B for storage until use.

[0042] 4. The obtained filtrate A and the above-mentioned obtained filtrate B are compatible according to the ratio of the crude drug amount, c...

Embodiment 3

[0047] 1. Take 20 kg of honeysuckle medicinal material (food material), which is identified as the flower bud of Lonicera trichomes. Soaked in a solution containing 0.5% NaCl for 6 hours, washed and dried by a centrifuge to extract active ingredients.

[0048] 2. Use 180L of pure water and hydrochloric acid to adjust the pH value of the soaked honeysuckle medicinal material (food material) to 5.5, use low temperature (50°C) countercurrent extraction, cool the extract, let it stand for 6 hours and filter, collect the filtrate A and save it for later use.

[0049] 3. Using the medicinal dregs collected after countercurrent extraction as raw materials, use high-temperature continuous thermal extraction (110°C) to collect volatile oil fractions, cool rapidly, let stand for 6 hours, filter, and collect filtrate B for storage until use.

[0050] 4. The obtained filtrate A and the above-mentioned obtained filtrate B are compatible according to the ratio of the crude drug amount, conc...

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PUM

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Abstract

The invention discloses a honeysuckle dew containing both chlorogenic acid and volatile oil components. The honeysuckle dew contains both chlorogenic acid and volatile oil components, the content of chlorogenic acid is greater than or equal to 10mg / 100ml, and its preparation method uses water as a solvent to extract the active ingredients in honeysuckle respectively in two stages, and the first stage adopts low temperature Countercurrent extraction of chlorogenic acid in honeysuckle, the second stage extracts the volatile oil components from the medicinal residues produced by the first stage of extraction, and then cools them separately, and then filters them according to the proportion of the crude drug. The obtained honeysuckle dew contains both chlorogenic acid and volatile oil components, which not only ensures that the honeysuckle dew has characteristic flavor, good color, and good taste, but also ensures that effective components such as chlorogenic acid, flavonoids, and aromatic components in the honeysuckle are effectively extracted. The advantage is that the obtained honeysuckle dew contains chlorogenic acid and aromatic substances at the same time to ensure clinical efficacy, and the obtained honeysuckle really has the functions of antibacterial, anti-inflammatory, anti-viral, anti-tumor, heat-clearing and detoxifying, and cooling and fire-removing.

Description

technical field [0001] This patent discloses a processing technology of traditional Chinese medicine preparation or health food. Specifically, it discloses a honeysuckle dew obtained by processing honeysuckle, a medicinal and edible material (foodstuff), and a preparation method thereof. Background technique [0002] Honeysuckle is also known as Erhua, Yinhua, and Double Flower. It is the flower bud of Lonicera Lonicera, Red Gland Lonicera, Mountain Silver Flower or Lonicera trichomes. It is distributed throughout the north and south of my country. It is cold in nature and sweet in taste. Traditional Chinese medicine believes that honeysuckle has heat-clearing and detoxifying, evacuating wind-heat; it is mainly used to treat diseases such as exogenous wind-heat, fever due to febrile disease, red and swollen throat, toxic heat and bloody dysentery, carbuncle and furuncle. [0003] Modern research shows that honeysuckle contains volatile oil, luteolin, flavonoids, chlorogen...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/355A61P31/04A61P31/10A61P31/12A61P35/00A61P29/00A61P39/02A23L2/38A23L33/00
CPCA23L2/38A61K36/355A61K2236/39A61K2236/53A61K2236/331A23V2002/00A23V2200/30
Inventor 陈运中
Owner HUBEI UNIV OF CHINESE MEDICINE
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