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Novel alginate dressing and preparation method thereof

A technology of alginate and alginate fiber, which is applied in the direction of conjugated rayon, chemical post-treatment of rayon, chemical characteristics of fibers, etc. The space for liquid expansion, reducing the amount of exudate absorption, etc., to achieve good biodegradability, good gelability and biocompatibility, and prevent contamination of wounds.

Inactive Publication Date: 2017-02-01
GUANGZHOU RAINHOME PHARM&TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the alginate dressings on the market are made of disordered alginate fibers, which greatly limits the space for the alginate to absorb and expand, reduces the amount of exudate absorbed, and is not easy to flow the exudate, further limiting the The absorption of alginate to exudate, thus affecting the absorption of wound exudate and wound protection effect of alginate dressing

Method used

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  • Novel alginate dressing and preparation method thereof
  • Novel alginate dressing and preparation method thereof
  • Novel alginate dressing and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0035] Such as figure 1 As shown, a new type of alginate dressing, the alginate dressing is constructed from alginate fibers in an orderly manner, and is a single-layer sheet structure with a uniformly distributed microporous structure. The pores of the microporous structure Area is 300μm 2 .

[0036] The alginate is sodium alginate and potassium alginate, both of which have a molecular weight of 2,000-200,000.

[0037] The grammage of the alginate dressing is 60g / cm 2 .

[0038] The porosity of the alginate dressing is 20%, and the shape of the holes is triangular.

[0039] When in use, either side of the alginate dressing is attached to the wound, and the medical adhesive tape is used to fix it on the surface of the wound. The alginate dressing has a uniformly distributed triangular microporous structure. When it is attached to the wound, the microporous structure can drain the exudate and provide a space for the dressing to expand after absorbing the exudate, thereby p...

Embodiment 2

[0041] Such as figure 2 As shown, a new type of alginate dressing, the alginate dressing is constructed from alginate fibers in an orderly manner, and is a single-layer sheet structure with a uniformly distributed microporous structure. The pores of the microporous structure Area is 1000μm 2 .

[0042] The alginate is sodium alginate and potassium alginate, both of which have a molecular weight of 2,000-200,000.

[0043] The gram weight of the alginate dressing is 80g / cm 2 .

[0044] The porosity of the alginate dressing is 50%, and the shape of the holes is triangular.

[0045]When in use, either side of the alginate dressing is attached to the wound, and the medical adhesive tape is used to fix it on the surface of the wound. The alginate dressing has a uniformly distributed triangular microporous structure. When it is attached to the wound, the microporous structure can drain the exudate and provide a space for the dressing to expand after absorbing the exudate, there...

Embodiment 3

[0047] Such as image 3 As shown, a new type of alginate dressing, the alginate dressing is constructed from alginate fibers in an orderly manner, and is a single-layer sheet structure with a uniformly distributed microporous structure. The pores of the microporous structure The area is 30000μm 2 .

[0048] The alginate is sodium alginate and potassium alginate, both of which have a molecular weight of 2,000-200,000.

[0049] The gram weight of the alginate dressing is 120g / cm 2 .

[0050] The porosity of the alginate dressing is 80%, and the shape of the holes is triangular.

[0051] When in use, either side of the alginate dressing is attached to the wound, and the medical adhesive tape is used to fix it on the surface of the wound. The alginate dressing has a uniformly distributed triangular microporous structure. When it is attached to the wound, the microporous structure can drain the exudate and provide a space for the dressing to expand after absorbing the exudate,...

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Abstract

The invention discloses a novel alginate dressing. The alginate dressing is prepared by constructing alginate fibers in sequence, and is of a single-layer flaky structure with uniformly distributed micro pores, wherein the area of each micro pore of the structure is 300-30,000 micrometers<2>. The invention further discloses a preparation method of the novel alginate dressing which is prepared by using a patterning electrode static spinning method with additional circular rings. The prepared alginate dressing is a piece of non-woven cloth, is of a sequential micro pore structure, has a ventilation function and is beneficial to alginate absorption and swelling, the absorption capacity of seepage can be increased, and a formed alginate gel layer has functions of covering wounds and protecting the wounds.

Description

technical field [0001] The invention belongs to the field of medical supplies, and in particular relates to a novel alginate dressing and a preparation method thereof. Background technique [0002] Alginate is a salt of alginic acid, a polymer of anhydrous D-mannuronic acid, highly hydrophilic, gel-like and biodegradable alginate, widely used in clinical wet dressings . Studies have shown that alginate functional dressing is a type of dressing made of alginate. It is as soft as gauze, has good sticking properties, and has strong absorption. It can absorb 20 times its own weight. liquid. Many clinical trials have proved that medical dressings made of alginate fibers not only have good hygroscopicity, but also promote wound healing better than traditional gauze. Alginate medical dressings are easy to clean when changing, avoiding the need for traditional dressings Secondary injury caused by adhesion to the wound. [0003] During the production process, alginic acid is conv...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/42D01F8/18D01F11/00
CPCA61L15/28A61L15/425D01F8/18D01F11/00
Inventor 张聪赵澎钟经德车七石刘少辉
Owner GUANGZHOU RAINHOME PHARM&TECH CO LTD
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