Method for preventing overstimulation syndrome and application

Abstract

The invention belongs to the field of gynecological disease prevention and treatment and relates to a new method for preventing overstimulation syndrome. The method is characterized by comprising the following steps: after injecting GnRHa for 12 hours according to an antagonist scheme, applying 0.2mg triptorelin acetate for injection; extracting blood and checking serum sex hormone and urine LH; after 24 hours, conventionally taking ovum, cancelling transplanting and utilizing transvaginal ultrasonography to closely examine the ovary size change of the patient. According to the invention, the operation is simple and convenient; the therapeutic effect is obvious; the serious OHSS risk of the patient caused by the OHSS ultrahigh risk can be obviously reduced and eliminated, so that the accordingly caused serious medical disputes can be avoided; uncomfortable body and mental stress caused by serious OHSS can be reduced and even eliminated; time and cost caused by other precautionary measures and hospitalization for preventing OHSS can be reduced; the safety of assisted fertility therapy can be obviously increased; the method can be widely applied to the assisted fertility therapy in the hospital.

Description

technical field [0001] The invention belongs to the field of prevention and treatment of gynecological diseases, and relates to a new method for preventing ovarian hyperstimulation syndrome (ovarian hyperstimulation syndrome, OHSS) in in vitro fertilization-embryo transfer (in vitro fertilization and embryo transfer, IVF-ET) and its Clinical application, it can be used in patients with high response to controlled ovulation stimulation in IVF cycle to prevent or even eliminate the occurrence of ovarian hyperstimulation syndrome. Background technique [0002] At present, due to the acceleration of the pace of work, the increasing pressure of job competition, and the combined influence of other factors such as environmental pollution, the number of infertility patients is increasing day by day. The use of hyperovulation stimulation in clinical work causes the patient to develop multiple follicles, and IVF-ET for conception has become an effective medical method, but the resulti...

AI Technical Summary

Problems solved by technology

Although multi-channel symptomatic treatment can alleviate the patient's discomfort to a certain extent, it cannot completely avoid the occurrence of severe ovarian hyperstimulation syndrome, and severe OHSS significantly increases the patient's physical discomfort and mental stress. Increase the patient's treatment time and medical expenses, and may even cause serious medical disputes

[0004] The current international gold standard for the prevention of OHSS is "antagonist regimen plus gonadotropin releasing hormone agonist (GnRHa) to promote the final maturation of oocytes, and cancel fresh cycle embryo transfer", which is relatively The long-term ovulation induction program has significantly reduced the incidence of OHSS, especially moderate and severe OHSS, but it still cannot eliminate the occurrence of OHSS

Images